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| 1 | Chronic constipation in hemiplegic patients显示文摘AIM: To assess the prevalence of bowel dysfunction in hemiplegic patients, and its relationship with the site of neurological lesion, physical immobilization and pharmacotherapy. METHODS: Ninety consecutive hemiplegic patients and 81 consecutive orthopedic patients were investigated during physical motor rehabilitation in the same period, in the same center and on the same diet. All subjects were interviewed ≥ 3 mo after injury using a questionnaire inquiring about bowel habits before injury and at the time of the interview. Patients’ mobility was evaluated by the Adapted Patient Evaluation Conference System. Drugs considered for the analysis were nitrates, angiogenic converting enzyme (ACE) inhibitors, calcium antagonists, anticoagulants, antithrombotics, antidepressants, anti-epileptics. RESULTS: Mobility scores were similar in the two groups. De novo constipation (OR = 5.36) was a frequent outcome of the neurological accident. Hemiplegics showed an increased risk of straining at stool (OR: 4.33), reduced call to evacuate (OR: 4.13), sensation of incomplete evacuation (OR: 3.69), use of laxatives (OR: 3.75). Logistic regression model showed that constipation was significantly and independently associated with hemiplegia. A positive association was found between constipation and use of nitrates and antithrombotics in both groups. Constipation was not related to the site of brain injury. CONCLUSION: Chronic constipation is a possible outcome of cerebrovascular accidents occurring in 30% of neurologically stabilized hemiplegic patients. Its onset after a cerebrovascular accident appears to be independent from the injured brain hemisphere, and unrelated to physical inactivity. Pharmacological treatment with nitrates and antithrombotics may represent an independent risk factor for developing chronic constipation. | F Bracci D Badiali P Pezzotti G Scivoletto U Fuoco L Di Lucente A Petrelli E Corazziari | 2007 | World Journal of Gastroenterology2007,13,29: | 15 |
| 2 | Nerve growth factor:from neurotrophin to neurokine显示文摘 | Levi-Montalcini R Skaper SD Dal Toso R Petrelli L Leon A | 1996 | Trends Neurosci1996,19,11: | 1 |
| 3 | Postprandial blood glucose is a stronger predictor of cardiovascular events than fasting blood glucose in type 2 diabetes mellitus,particularly in women:lessons from the San Luigi Gonzaga Diabetes Study显示文摘 | Cavalot F Petrelli A Traversa M | 2006 | J Clin Endocrinol Metab2006,91,3: | 1 |
| 4 | Radiotherapy with concurrent cisplatin-based doublet or weekly cisplatin for cervical cancer: a systematic review and recta-analysis 显示文摘 | Petrelli F De Stefani A Raspagliesi F | 2014 | Gynecol Oncol2014,134,1: | 1 |
| 5 | Early postoperative oral feeding after colectomy: an analysis of fators that may predict failure显示文摘 | Petrelli N J Cheng C Driscoll D et a l | 2001 | Ann Surg Oncol2001,8,10: | 1 |
| 6 | Guidelines 2000for colonand rectal cancer surgery显示文摘 | Nelson H Petrelli N Carlin A | 2001 | J Natl Cancer Inst2001,93,8: | 1 |
| 7 | Postprandial bloodglucose is a stronger predictor of cardiovascular events thanfasting blood glucose in type 2 diabetes mellitus,particularlyin women: lessons from the San Luigi Gonzaga Diabetes Study显示文摘 | Cavalot F Petrelli A Traversa M | 2006 | J Clin Endocrinol Metab2006,91,3: | 1 |
| 8 | Guidelines 2000 for colon and rectal cancer surgery显示文摘 | Nelson H Petrelli N Carlin A | 2001 | J Natl Cancer Inst2001,93,8: | 1 |
| 9 | Guidelines 2000 for colon and rectal cancer surgery 显示文摘 | Nelson H Petrelli N Carlin A | 2001 | J Natl Cancer Inst2001,93,8: | 1 |
| 10 | Adenosquamous carcinoma of the colon and rectum显示文摘 | Petrelli N J Valle A A Weber T K | 1996 | Dis Colon Rectum1996,39,: | 1 |
| 11 | Guidelines 2000 for colon and rectal cancer surgery 显示文摘 | Nelson H Petrelli N Carlin A | 2001 | Natl Cancer Inst2001,93,8: | 1 |
| 12 | Guidelines 2000 for colon and rectal cancer surgery 显示文摘 | Nelson H Petrelli N Carlin A | 2001 | J Natl Cancer Inst2001,93,8: | 1 |
| 13 | Postprandial blood glucose Is a stronger predictor of cardiovascular events than fasting blood glucose in type 2 diabetes mellitus, particularly in women: lessons from the San Luigi Gonzaga diabetes study显示文摘 | Cavalot F Petrelli A Traversa M | 2006 | The Journal of Clini- cal Bndocfinology & Metabolism2006,91,3: | 1 |
| 14 | Guidelines 2000 for colon and rectal cancer surgery 显示文摘 | Nelson H Petrelli N Carlin A | 2001 | J Natl Cancer Inst2001,93,8: | 1 |
| 15 | Guidelines 2000 for colon and rectal cancer surgery显示文摘 | Nelson H Petrelli N Carlin A | 2001 | Journal of the National Cancer Institute2001,93,8: | 1 |
| 16 | Prognostic factors for survival with bevacizumab - based therapy in coloreetal cancer patients: a systematic review and pooled analysis of 11,585 patients 显示文摘 | Petrelli F Coinu A Cabiddu M | 2015 | Med Oncol2015,32,2: | 1 |
| 17 | Efficacy of oxaliplatin-based chemotherapy + bevacizumab as first-line treatment for advanced colorectal cancer: a systematic review and pooled analysis of pub-lishedtrials显示文摘 | Petrelli F Coinu A Ghilardi M | 2015 | AmJClinOncol2015,38,2: | 1 |
| 18 | Ab-indu- ted ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity 显示文摘 | PETRELLI A CIRCOSTA P GRANZIERO L | 2006 | Proc Natl Acad Sci2006,103,13: | 1 |
| 19 | Radical prostatectomy or radiotherapy in high-risk prostate cancer: a systematic review and metaanalysis 显示文摘 | Petrelli F Vavassori I Coinu A | 2014 | Clin Genitoarin Cancer2014,12,: | 1 |
| 20 | Radiotherapy with concurrent cisplatin-based doublet or weekly cisplatin for cervical cancer:A systematic review and meta-analysis 显示文摘 | Petrelli F De Stefani A Raspagliesi F | 2014 | Gynecol Oncol2014,134,1: | 1 |