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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | Degradation Mechanisms of Vertical Cavity Surface Emitting Lasers, Quantum Electronics显示文摘 | Michael C Y Robert W H Pierre M P | 1996 | IEEE Journal1996，32，： | 2 |
| 3 | Tricuspid valve replacement: an analysis of 25 years of experience at a single center显示文摘 | Michel Carrier Yves Hébert Michel Pellerin Denis Bouchard Louis P Perrault Raymond Cartier Arsène Basmajian Pierre Pagé Nancy C Poirier | 2003 | The Annals of Thoracic Surgery2003，，1： | 1 |
| 4 | Physiological effects of medium-chain triglycerides: potential agents in the prevention of obesity显示文摘 | PIERRE M ONGE S JONES P J H | 2002 | The American Society for Nutritional Sciences: Journal of Nutrition2002，132，： | 1 |
| 5 | Profile accumulation of fertilizer derived nitrate and total nitrogen recovery in two long-term nitrogen-rate experiments with corn 显示文摘 | Von Jolley D P Pierre W H | 1977 | Soil Sci Soc Am J1977，41，： | 1 |
| 6 | Volume velocity control of sound transmission through composite panels显示文摘 | Pierre P L Koopmann G H Chen W | 1998 | Journal of Sound and Vibration1998，210，4： | 1 |
| 7 | Steroid saponins from fenugreek seeds:extraction,purification,and pharmacological investigation on feeding behavior and plasma cholesterol显示文摘 | Pierre R P Yves D S Dominique M H | 1995 | Steroids1995，60，10： | 1 |
| 8 | A theoretically-based model for predicting total digestible nutrient values of forages and concentrates显示文摘 | Wesis W P Conrad H R Pierre N R S | 1992 | Anita Feed Sci Technol1992，39，： | 1 |
| 9 | Monocyte-derived dendritic cells induce a house dust mite-specific Th2 allergic inflammation in the lung of humanized SCID mice: involvement of CCR7 显示文摘 | Hamida H BartN L Pierre P | 2002 | J Immunol2002，169，3： | 1 |
| 10 | Monocyte- derived dendritic cells induce a house dust mite-specific Th2 allergic inflammation in the lung of humanized SCID mice: involvement ofCCR7 显示文摘 | Hamida H Bait N L Pierre P | 2002 | J Immunol2002，169，： | 1 |
| 11 | Predicting blade stress levels directly from reduced-order vibration models of mistuned bladed disks显示文摘 | Lim S H Pierre C Castanier Matthew P | 2006 | Journal of Turbomachinery2006，128，1： | 1 |
| 12 | A theoretically-based model for predicting total digestible nutrient values of forages and concentrates显示文摘 | Weiss W P Conrad H R Pierre N R St | 1992 | Animal Feed Science Technology1992，39，： | 1 |
| 13 | Satellite Traking and Avian Conser ration in Asia显示文摘 | Higuchi H Pierre J P | 2005 | Landscape Ecol Eng2005，1，1： | 1 |
| 14 | Steroid saponins from fenugreek seeds:extraction,purification,and pharmacological investigation on feeding behavior and plasma cholesterol显示文摘 | Pierre R P Yves D S Dominique M H | 1995 | Steroids1995，60，10： | 1 |
| 15 | A new technical approach to quantify cell-cell adhesion forces by AFM显示文摘 | PIERRE H P KATE P DETLEF K | 2006 | Uhramicroscopy2006，106，89： | 1 |
| 16 | Monocyte-derived dendritic cells induce a house dust mite-specific Th2 allergic inflammation in the lung of humanized SCID mice:involvement of CCR7显示文摘 | Hamida H Bart N L Pierre P | 2002 | J Immunol2002，169，： | 1 |
| 17 | Human ovarian tissue cryopreservation:indications and feasibility显示文摘 | Catherine P Marie-Cécile Vacher-Lavenu Pierre H | 2002 | Hum Reprod2002，17，1： | 1 |
| 18 | Evolutionary models of halo stars with rotation I-Evidence for differential rotation with depth in stars 显示文摘 | Pinsonneault T M H Deliyannis Constantine P Demarque Pierre | 1991 | Astrophysical Journal1991，367，： | 1 |
| 19 | Sonochemical degradation of phenol in water: a comparison of classical equipment with a new cylindrical reactor显示文摘 | MOHAMMAD H E CHRISTIAN P PIERRE D | 2003 | Ultrasonics Sonochemistry2003，10，： | 1 |
| 20 | Rapid determination of valaciclovir and acyclovir in human biological fluids by high-performance liquid chromatography using isocratic elution显示文摘 | CHUONG P H FOTOULA S PIERRE S | 1999 | J Chromatogr B Biomed Sci Appl1999，732，1： | 1 |
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