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| 1 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 2 | Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor,ENMD-2076,against multiple myeloma显示文摘 | WANG X J SINN A L POLLOK K | 2010 | Br J Haematol2010，150，3： | 1 |
| 3 | PET imaging and optical imaging with D-lueiferin methyl es- ter and D-luciferin methyl ether of luciferase gene expression in tumor xenografts of living mice 显示文摘 | Wang J-Q Pollok K E Cai S | 2006 | Bioorganic & Medicinal Chemistry Letters2006，16，2： | 1 |
| 4 | A theoretically optimized method for cord blood stem cell cryopreservation显示文摘 | Woods E J Liu J Pollok K | 2003 | J of Hemato and Stem Cell Res2003，12，： | 1 |
| 5 | Lentiviral vectors pseudotyped with glycoproteins from Ross River and vesicular stomatitis viruses: variable transduction related to cell type and culture conditions 显示文摘 | Kahl CA Pollok K Haneline LS | 2005 | Mol Ther2005，11，3： | 1 |
| 6 | Patients with sold tumors treated with high-temperature whole body hyperthermia show a redistribution d native/memory T-cell subtypes 显示文摘 | Atanackovic D pollok K Faltz C | 2006 | Am J Physiol Regal Integrcomp Physiol2006，290，3： | 1 |
| 7 | Interrelations of breed type, USDA quality grade, cooking method and degree of doneness on consumer evaluations of beef in Dallas and San Antonio, Texas, USA 显示文摘 | McKenna D R Lorenzen C L Pollok K D | 2004 | Meat Science2004，66，2： | 1 |
| 8 | Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma 显示文摘 | WANG X SINN A L POLLOK K | 2010 | Br J Haematol2010，150，3： | 1 |
| 9 | A theoretically optimized method for cord blood stem cell cryopreservation显示文摘 | Woods EJ Liu J Pollok K | 2003 | J Hematother Stem Cell Res2003，12，： | 1 |
| 10 | Patients with solid tumors treated with high-temperature whole body hyperthermia show a redistribution of naive/memory T-cell subtypes显示文摘 | Atanackovic D Pollok K Faltz C | 2006 | Am J Physiol Regul Integr Comp Physiol2006，290，3： | 1 |
| 11 | Green fluorescent protein as selectable marker of fibronectin-facilitated retroviral gene transfer in primary human T lymphocytes显示文摘 | Noraz N Pollok k | 1999 | Human Gene Therapy1999，10，1： | 1 |
| 12 | Role of colectomy in preventing recurrent primary sclerosing cholangitis in liver transplant recipients显示文摘AIM To study the published evidence on the impact of colectomy in preventing recurrent primary sclerosing cholangitis(r PSC). METHODS An unrestricted systematic literature search in Pub Med, EMBASE, Medline Ovid SP, ISI Web of Science, Lista(EBSCO) and the Cochrane library was performed on clinical studies investigating colectomy in liver transplantation(LT) recipients with and without r PSC in the liver allograft. Study quality was evaluated according to a modification of the methodological index for non-randomized studies(MINORS) criteria. Primary endpoints were the impact of presence, timing and type of colectomy on r PSC. Overall presence of inflammatory bowel disease(IBD), time of IBD diagnosis, posttransplant IBD and immunosuppressive regimen were investigated as secondary outcome.RESULTS The literature search yielded a total of 180 publications. No randomized controlled trial was identified. Six retrospective studies met the inclusion criteria of which 5 studies were graded as high quality articles. Reporting of IBD was heterogenous but in four publications, either inflammatory bowel disease, ulcerative colitis or in particular active colitis post-LT significantly increased the risk of r PSC. The presence of an intact(i.e., retained) colon at LT was identified as risk factor for r PSC in two of the high quality studies while four studies found no effect. Type of colectomy was not associated with r PSC but this endpoint was underreported(only in 33% of included studies).Neither tacrolimus nor cyclosporine A yielded a significant benefit in disease recurrence of primary sclerosing cholangitis(PSC).CONCLUSION The data favours a protective role of pre-/peri-LT colectomy in r PSC but the current evidence is not strong enough to recommend routine colectomy for r PSC prevention. | Bettina M Buchholz Panagis M Lykoudis Reena Ravikumar Joerg M Pollok Giuseppe K Fusai | 2018 | World Journal of Gastroenterology2018，24，28： | 1 |
| 13 | Patients with solid tumors treated with high -temperature whole body hyperthermia show a redistribution of naive/memory T-cell subtypes 显示文摘 | Atanaekovic D Pollok K Faltz C | 2006 | Am J Physiol Regul Integr Comp Physiol2006，290，3： | 1 |
| 14 | Liver derived pro-inflammatory cytokines may be important in producing intracranial hypertension in acute liver failure显示文摘 | Rajiv Jalan Anthony Pollok Syed H.A Shah Krishna K Madhavan Kenneth J Simpson | 2002 | Journal of Hepatology2002，，4： | 1 |
| 15 | Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma 显示文摘 | WANG X J SINN A L POLLOK K | 2010 | Br J Haematol2010，150，3： | 1 |
| 16 | Patients with solid tumors treated with high-temperature whole bgdy hyperthermia show a redistribution of naive/memory T-cell subtypes显示文摘 | Atanackovic D Pollok K Fahz C | 2006 | American Journal of Physiology Regulatory Integrative and Comparative Physiology2006，290，3： | 1 |
| 17 | Altered pattern of motor cortical activation-inhibition during voluntary movements in Tourette syndrome显示文摘 | Franzkowiak S Pollok B Biermann-Ruben K | 2010 | Mov Disord2010，25，12： | 1 |
| 18 | Green fluorescent protein as a selectable marker of fibronectin-facilitated retroviral gene transfer in primary human T lymphocytes显示文摘 | DARADALHON Y NORAZ N POLLOK K | 1999 | Hum Gene Ther1999，10，： | 1 |
| 19 | Tissue engineering显示文摘 | POLLOK J K VACANTI J P | 1996 | Semin Pediatr Surg1996，5，： | 1 |
| 20 | Comparison of midazolam with propofol for sedation in outpatient bronchoscopy显示文摘 | Crawford M Pollok J Anderson K | 1993 | Br J Anaesth1993，70，4： | 1 |
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