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| 1 | Feeder-free maintenance of hESCs in mesenchymal stem cell-conditioned media: distinct requirements for TGF-β and IGF-Ⅱ显示文摘 | Rosa Montes Gertrudis Ligero Laura Sanchez Purificacidn Catalina Teresa de la Cueva Ana Nieto Gustavo J Melen Ruth Rubio Javier Garcia-Castro Clara Bueno Pablo Menendez | 2009 | Cell Research2009,19,6: | 7 |
| 2 | 胸腰段脊柱骨折定量影像学显示文摘描述影响胸腰段脊柱不同类型骨折,以及指导脊柱骨折治疗的不同分类及关键影响因素。目前脊柱骨折分类以Denis三柱模型为基石,包括压缩性骨折、爆裂性骨折、屈曲牵张骨折和骨折伴脱位。骨折分类系统包括胸腰椎损伤分类和严重程度评分(Thoracolumbar Injury Classification and Severity Score,TLICS)系统和AO脊柱胸腰椎损伤分类和严重程度评分(AOSpine-TLICS)。正确分类需要定量成像方法,采用多个测量指标来评定其属于不同TLICS或AOSpine-TLICS类型。如果TLICS评分>4或者AOSpine-TLICS评分>5,则患者需要手术治疗。本文重点描述X线片、CT及MRI影像表现和测量参数,包括爆裂性骨折患者中椎体楔形变成角和压缩性骨折椎体高度丢失百分比、椎弓根间距和腰椎管狭窄程度以及一些严重骨折(如屈曲牵张骨折、骨折伴脱位)患者的椎体位移和棘突间距增加。通过图解和影像案例展现这些影像学特征和相关参数。 | Fernando Ruiz Santiago Pablo Tomas Munoz Elena Moya Sanchez Marta Revelles Paniza Alberto Martinez Martinez Antonio Luis Perez Abela | 2017 | 临床与病理杂志2017,37,4: | 7 |
| 3 | A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification显示文摘MLL-AF4 熔化基因是在在婴儿的高风险的尖锐成淋巴细胞的白血病的一个特点 genomic 错误。尽管 MLL-AF4 在人的开发期间出生前地产生,这很好被建立,它在在 utero 的造血的开发的效果仍然保持未经勘探。我们创造了一个人特定的细胞的系统在 MLL-AF4-expressing 人的胚胎的干细胞(hESCs ) 学习早 hemato-endothelial 开发。介绍的功能的研究,同种细胞的分析和基因表示表明在 hESCs 的 MLL-AF4 的那表情有 phenotypic,功能并且基因表示影响。MLL-AF4 在 hESCs 充当全球 transcriptional 使活跃之物和 homeobox 基因表示的一个积极管理者。机能上地, MLL-AF4 从 hESCs 提高 hemogenic 先锋的说明,但是强烈损害进一步造血的承诺赞成 endothelial 房间命运。MLL-AF4 hESCs transcriptionally 被告知向对 endothelial 成熟敏感的 hemogenic 先锋区分,由联系到 vascular-endothelial 功能和早造血作用的主人基因的显著 upregulation 思考了。而且,我们报导那 MLL-AF4 表情不是足够的转变导出 hESC 的造血的房间。这个工作说明 hESCs 怎么可以提供唯一的卓见进人的开发并且推进我们理解白血病的熔化基因,知道出生前地产生,调整人的胚胎的造血的说明。 | Clara Bueno Rosa Montes Gustavo J Melen Verdnica Ramos-Mejia Pedro J Real Ver6nica Ayllo'n Laura Sanchez Gertmdis Ligero Inmaculada Gutierrez-Aranda Agustin F Femfindez Mario F Fraga Inmaculada Moreno-Gimeno Deborah Btlrks Maria del Carmen Plaza-Calonge Juan C Rodriguez-Manzaneque Pablo Menendez | 2012 | Cell Research2012,22,6: | 2 |
| 4 | Development of a solid phase dispersion - pressurized liquid extraction method for the analysis of suspected fragrance allergens in leave -on cosmetics显示文摘 | PABLO LAMAS J SANCHEZ - PRADO L | 2010 | Journal ofChromatography A2010,1217,52: | 1 |
| 5 | 'Occult' ectopic ACTH secretion syndrome:a case report显示文摘 | Garcia Puente I Sanchez Moro V de Pablos Velasco P | 2000 | An Med Interna2000,17,: | 1 |
| 6 | 'Occult'ectopic ACTH secretion syndrome:a case report显示文摘 | Garcia Puente I Sanchez Moro V de Pablos Velasco P | 2000 | An Med Intema2000,17,: | 1 |
| 7 | Benefits of a home - based physical exercise program in elderly subjects with type 2 diabetes mellitus 显示文摘 | Ferrer - Garcta JC Sanchez Lopez P Pablos - Abella C | 2011 | Endocrinol Nutr2011,58,8: | 1 |
| 8 | Root anato- my and canal configuration of the permanent mandibular first molar: a systematic review显示文摘 | De Pablo OV Estevez R Sanchez MP | 2010 | J Endod2010,36,12: | 1 |
| 9 | Spacecraft Thruster Control Allocation Problems显示文摘 | Pablo A Servidia Ricardo Sanchez Pena | 2005 | IEEE Transactions on Automatic Control2005,50,2: | 1 |
| 10 | 'Occult' ectopic ACTH secretion syndrome:a case report显示文摘 | Garcia Puente I Sanchez Morn V de Pablos Velascn P | 2000 | An Med Intema2000,17,: | 1 |
| 11 | Soluble Angiogenic Factors in Patients With Acute Pancreatitis显示文摘 | Laura Espinosa Pablo M. Linares Alicia Bejerano Cristina Lopez Argeme Sanchez Ricardo Moreno-Otero Javier P. Gisbert | 2011 | Journal of Clinical Gastroenterology2011,,7: | 1 |
| 12 | 'Occult' ectopic ACTH secretion syndrome:a case report显示文摘 | Garcia Puente I Sanchez Moro V de Pablos Velasco P | 2000 | An Med Interna2000,17,11: | 1 |
| 13 | Nonsteroidal anti-inflammatory drug effectivity in preventing postendoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis显示文摘BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is the primary therapeutic procedure for the treatment of diseases affecting the biliary tree and pancreatic duct.Although the therapeutic success rate of ERCP is high,the procedure can cause complications,such as acute pancreatitis[post-ERCP pancreatitis(PEP)],bleeding and perforation.AIM To assess the efficacy of non-steroidal anti-inflammatory drugs(NSAIDs)in preventing PEP during follow-up.METHODS Databases such as MEDLINE,EMBASE and Cochrane Central Library were searched.Only randomized controlled trials(RCTs)comparing the efficacy of NSAIDs and placebo for the prevention of PEP were included.Outcomes evaluated included the incidence of PEP,severity of pancreatitis,route of administration,types,dose,and timing of administration of NSAIDs.RESULTS Twenty-six RCTs were considered eligible with a total of 8143 patients analyzed.Overall,4020 patients used NSAIDs before ERCP and 4123 did not use NSAIDs(control group).Ultimately,298 cases of post-ERCP acute pancreatitis were diagnosed in the NSAID group and 484 cases in the placebo group.The risk of PEP was lower in the NSAID group risk difference(RD):-0.04;95%confidence interval(CI):-0.07 to-0.03;number needed to treat(NNT),25;P<0.05.NSAID use effectively prevented mild pancreatitis compared to placebo use(2.5%vs 4.1%;95%CI:-0.05 to-0.01;NNT,33;P<0.05),but information on moderate PEP and severe PEP could not be fully elucidated.Only rectal administration reduced the incidence of PEP with RD:-0.06;95%CI:-0.08 to-0.04;NNT,17;P<0.05).Furthermore,only the use of diclofenac or indomethacin was effective in preventing PEP,at a dose of 100 mg,which must be administered before performing ERCP.CONCLUSION Rectal administration of diclofenac and indomethacin significantly reduced the risk of developing mild PEP.Additional RCTs are needed to compare the efficacy between NSAID routes of administration in preventing PEP. | Juan Pablo Román Serrano JoséJukemura Samuel Galante Romanini Paúl Fernando Guamán Aguilar Juliana Silveira Lima de Castro Isabela Trindade Torres JoséAndres Sanchez Pulla Otavio Micelli Neto Eloy Taglieri JoséCelso Ardengh | 2020 | World Journal of Gastrointestinal Endoscopy2020,12,11: | 1 |
| 14 | WOX4 Imparts Auxin Responsiveness to Cambium Cells in Arabidopsis(C)(W)(OA)显示文摘 | Suer Stefanie Agusti Javier Sanchez Pablo Schwarz Martina Greb Thomas | 2011 | EN2011,,9: | 1 |
| 15 | Understanding local C02 emissions reduction targets 显示文摘 | Pablo R M Pozo B R Sanchez B A | 2015 | Renewable and Sustainable Energy Reviews2015,48,: | 1 |
| 16 | Development and Test of an Experimental Apparatus to Study Thermal-Choking in Ideal Gases and Self-decomposition in Superheated N2O显示文摘 | Patrick Lemieux Alberto Fara Pablo Sanchez William Murray | 2015 | Journal of Energy and Power Engineering2015,9,1: | 0 |
| 17 | 2-Nitrobenzofuran as Dienophile in Polar Diels-Alder Reaction: A Simple Dibenzofurans Synthesis显示文摘 | Claudia Daniela Della Rosa Juan Pablo Sanchez Maria Nelida Kneeteman Pedro Maiximo Emilio Mancini | 2010 | Journal of Chemistry and Chemical Engineering2010,4,11: | 0 |
| 18 | REVIEWS显示文摘Review article: Raoul McLaughlin, Rome and the Distant East. Trade routes to the Ancient Lands of Arabia, India and China, Continuum, 2010. Dr. Raoul McLaughlin (http://www.raoul-mclaughlin.net/) studied Archaeology | Juan Pablo Sanchez | 2011 | Journal of Ancient Civilizations2011,26,1: | 0 |