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| 1 | In vitro antiplasmodial effect of ethanolic extracts of traditional medicinal plant Ocimum species against Plasmodium falciparum显示文摘Objective:To identify the possible antiplasmodial compounds from leaf,stem,root and flower extracts of Ocimum canum(O.canum),Ocimum sanctum(O.sanctum) and Ocimum basilicum (O.basilicum).Methods:The O.canum,O.sanctum and O.basilicum were collected from Ramanalhapuram District,Tamil Nadu and the extraction was carried out in ethanol.The filter sterilized extracts(100,30,23,12.5,6.23 and 3.125μg/mL) of leaf,stem,root and flower extracts of O.canum,O.sanctum and O.basilicum were tested for antiplasmodial activity against Plasmodium falciparum(P.falciparum).The potential extracts were also tested for their phytochemical constituents.Results:The leaf extract of O.sanctum showed excellent antiplasmodial activity(IC50 3538μg/mL) followed by leaf extract of O.basilicum(IC50 4341μg/mL). The leaf extract of O.canum,root extracts of O.sanctum and O.basilicum,the stem and flower extracts of all the three tested Ocimum species showed IC50 values between 50 and 100μg/mL Statistical analysis reveals that,significant antiplasmodial activity(P<0.01) was observed between the concentrations and time of exposure.The chemical injury to erythrocytes was also carried out and it shows that,there were no morphological changes in erythrocytes by the ethanolic extract of O.canum,O.sanctum and O.basilicum.The in vitro antiplasmodial activity might be due to the presence of alkaloids,glycosides,flavonoids,phenols,saponins,triterpenoids,proteins,resins, steroids and tannins in the ethanolic extracts of tested plants.Conclusions:The ethanolic leaf extracts of O.sanctum possess lead compounds for the development of antiplasmodial drugs. | Samuel Jacob Inbaneson Sundaram Ravikumar Palavesam Suganthi | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，2： | 3 |
| 2 | In vitro antiplasmodial effect of ethanolic extracts of coastal medicinal plants along Palk Strait against Plasmodium falciparum显示文摘Objective:To identify the possible anliplasmodial compounds from Achyranlhes aspera(A. aspera).Acalypha indica(A.indica),Jatropha glandulifera(J.glanduUfera)and Phyllanlhus amarus(P.amarus).Methods:The A.aspera,A.indica,J.glandulifera and P.ainarus were collected along Palk Strait and the extraction was carried out in ethanol.The filter sterilized extracts(100,50,25,12.5,6.25 and 3.125μg/mL) of leaf,stem,root and flower extracts of A aspera,A. indica,J.glandulifera and P.amarus were tested for anliplasmodial activity against Plasnuxlium falciparum.The potential extracts were also tested for their phytochemical constituents.Results: Of the selected plants species parts,the stem extract of A.indica showed excellent antiplasmodial activity(IC_(50)=43.81μg/mL) followed by stem extract of J.glandulifera(IC_(50)= 49.14μg/mL).The stem extract of A.aspera,leaf and root extracts of A.indka,leaf,root and seed extracts of J. glanduUfera and leaf and stem extracts of P.amarus showed IC_(50),values between 50 and 100 μg/ mL.Statistical analysis revealed that,significant antiplasmodial activity(P<0.0l) was observed between the concentrations and time of exposure.The chemical injury to erythrocytes was also carried out and it showed that there were no morphological changes in erythrocytes by the elhanolic extract of all the tested plant extracts.The in vitro antiplasmodial activity might be due to the presence of alkaloids,glycosides,flavonoids.phenols,saponins,triterpenoids,proteins, and lannins in the elhanolic extracts of tested plants.Conclusions:The elhanolic stem extracts of P.amarus and J.glandulifera possess lead compounds for the development of antiplasmodial drugs. | Samuel Jacob Inbaneson Sundaram Ravikumar Palavesam Suganthi | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，5： | 2 |
| 3 | 中链脂肪酸的抗菌作用:辛酸对悉生卤虫无节幼体接种虾致病菌哈维氏弧菌和副溶血性弧菌的抗菌作用显示文摘试验目的是测定辛酸对培养基中的卤虫无节幼体接种了虾病原菌哈维氏弧菌和副溶血性弧菌的抗菌作用。首先,通过细菌生长试验研究不同浓度的辛酸(1,10和100 mM)对哈维氏弧菌和副溶血性弧菌抗菌效果。研究表明,100 mM浓度的辛酸,在5 h内病原体被完全抑制生长,然而,1 mM和10 mM浓度,有效的抑制时间延长。接着,通过细菌生长试验研究不同pH值(5~7)对辛酸(浓度为10 mM)抑制哈维氏弧菌和副溶血性弧菌抗菌效果的影响。与pH值6和7比较,在pH值5时,病原体生长非常少。卤虫无节幼体(龄II)饲养在含有10 mM辛酸的培养基中,然后接种哈维氏弧菌和副溶血性弧菌,记录60 h内的死亡率,每间隔6 h记录1次。研究发现,接种了哈维氏弧菌和副溶血性弧菌的卤虫无节幼体的死亡率分别降低到20.61%和16.3%。研究结果表明,辛酸对水产养殖中的发光弧菌具有潜在的抗菌活性。 | G. Immanuel M. Sivagnanavelmurugan A. Palavesam | 2014 | 饲料工业2014，35，20： | 2 |
| 4 | Antifouling activity of the methanolic extract of Syringodium isoetifolium , and its toxicity relative to tributyltin on the ovarian development of brown mussel Perna indica显示文摘 | P. Iyapparaj P. Revathi R. Ramasubburayan S. Prakash P. Anantharaman G. Immanuel A. Palavesam | 2012 | Ecotoxicology and Environmental Safety2012，，： | 1 |
| 5 | Dietary effect of Sargassum wightii fucoidan to enhance growth, prophenoloxidase gene expression of Penaeus monodon and immune re- sistance to Vibrio parahaemolyticus 显示文摘 | SIVAGNANAVELMURUGAN M THADDAEUS B J PALAVESAM A | 2014 | Fish and Shellfish Immunology2014，39，2： | 1 |
| 6 | AM fungal diversity in selected medicinal plants of Kanyakumari District, Tamil Nadu, India显示文摘 | Sundar S K Palavesam A Parthipan B | 2011 | lndian JMicrobiol2011，51，3： | 1 |
| 7 | Production and characterization of an antifungal compound (3-phenyllactic acid) produced by Lactobacillus plantarum strain显示文摘 | Prema P Smila D Palavesam A | 2010 | Technology2010，3，3： | 1 |
| 8 | Production and characterization of an antifungal compound(3-Phenyllactic Acid)produced by Lactobacillus plantarum strain显示文摘 | Prema P Smila D Palavesam A | 2010 | Food and Bioprocess Technology2010，，3： | 1 |
| 9 | In vitro antiplasmodial activity of ethanolic extracts of South Indian medicinal plants against Plasmodium falciparum显示文摘 | Sundaram Ravikumar Samuel Jacob Inbaneson Palavesam Suganthi | 2012 | Asian Pacific Journal of Tropical Disease2012，，3： | 1 |
| 10 | Production and characterization of an antifungal compound( 3- phenyllactic acid ) produced by Lactobacillus plantarum strain 显示文摘 | Prema P Smila D Palavesam A | 2010 | Food Bioprocess Technology2010，3，3： | 1 |
| 11 | Production and characterization of an antifungal compound (3-phenyllactic acid) produced by Lactobacillus plantarum strain 显示文摘 | Prema P Smila D Palavesam A | 2010 | Food Bioprocess Technology2010，3，： | 1 |
| 12 | Production and characterization of an antifungal compound (3-phenyllactic acid) produced by Lactobacillus plantarum strain显示文摘 | Prema P Smila D Palavesam A Immanuel G | | 0，，03： | 1 |
| 13 | Marian feeding trashfish Odonus niger lipid enriched Artemia nauplii on growth,stress resistance and HUFA requirements of Penaeus monodon postlarvae显示文摘 | Immanuel G Palavesam A Sivaram V M | 2004 | Aquaculture2004，，237： | 1 |
| 14 | Solid–state production of esterase using fish processing wastes by Bacillus altitudinis AP–MSU显示文摘 | Esakkiraj P Usha R Palavesam A | 2012 | food and bioproducts processing2012，，90： | 1 |
| 15 | Production and characteri- zation of an antifungal compound (3-phenyllactic acid) produced by Lac- tobacillus plantarum strain显示文摘 | PREMA P SMILA D PALAVESAM A | 2010 | Food Bioproe Teehnol2010，3，3： | 1 |
| 16 | Production and character- ization of an antifungal compound(3-phenyllactic acid) produced by LactobaciUus plantarum stain显示文摘 | P~aMA P SMILA D PALAVESAM A | 2010 | Food and Bioprocess Technology2010，3，3： | 1 |
| 17 | Use of electroporation as an option to transform the horn fly, Haematobia irritans: a species recalcitrant to microinjection显示文摘角苍蝇, Haematobia irritans,是在北美洲的牛的一个严肃的害虫。角苍蝇的控制首先依靠了杀虫药剂。然而,杀虫药剂的重使用在角苍蝇导致了杀虫药剂抵抗的发展。控制角苍蝇的新奇方法极大地被需要。转基因的技术是一个有效工具遗传上修改昆虫并且可以基于 genomic 途径导致害虫控制的新奇方法。这里,我们经由 electroporation 报导角苍蝇的调停 piggyBac 的转变。有 DsRed 的转变荧光灯标记蛋白质编码区域被单个苍蝇身体和蛹的案例的 PCR 分析验证并且 PCR 产品定序。然而,南部的污点分析没能显示 DsRed 基因集成于角苍蝇染色体。因此, electroporation 协议可能引起了 DsRed 基因集成于角苍蝇的细菌的共生者。 | Qiang Xu Felix D. Guerrero Azhahianambi Palavesam Adalberto A. Perez de Leon | 2016 | Insect Science2016，23，4： | 0 |
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