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| 1 | 聚乙二醇电解质散剂联合二甲硅油在结肠镜检查肠道准备中的应用效果观察显示文摘目的:探讨聚乙二醇电解质散剂(PEG)联合二甲硅油在结肠镜检查肠道准备中的应用效果。方法:行结肠镜检查的患者238例,随机分为研究组(聚乙二醇电解质散剂联合二甲硅油组)和对照组(甘露醇组),比较两种肠道准备方法在肠道清洁度、祛泡效果、耐受性、息肉检出率、术后腹胀程度方面的差异。结果:最终210例符合条件入组,纳入统计分析,210例患者均完成肠道准备和全结肠镜检查。与对照组相比,研究组肠道清洁度满意率为90.29%、祛泡效果满意率为98.05%、息肉检出率为18.45%均优于对照组,两组比较差异具有统计学意义(P<0.05);而研究组不良反应发生率、排便次数、术后腹胀发生率与对照组比较差异无统计学意义(P>0.05)。结论:PEG联合二甲硅油在结肠镜检查肠道准备中的效果优于传统肠道清洁剂甘露醇,患者安全性和耐受性较高,有利于改善视野,提高病变检出率,尤其是微小息肉及扁平息肉的检出率。 | 张淑芬 薛挥 李建宏 高梦琪 张拉 Muna Palikhe | 2020 | 陕西医学杂志2020，49，2： | 27 |
| 2 | Transjugular intrahepatic portosystemic shunt vs endoscopic therapy in preventing variceal rebleeding显示文摘AIM:To compare early use of transjugular intrahepatic portosystemic shunt(TIPS) with endoscopic treatment(ET) for the prophylaxis of recurrent variceal bleeding.METHODS:In-patient data were collected from 190 patients between January 2007 and June 2010 who suffured from variceal bleeding.Patients who were older than 75 years;previously received surgical treatment or endoscopic therapy for variceal bleeding;and complicated with hepatic encephalopathy or hepatic cancer,were excluded from this research.Thirty-five cases lost to follow-up were also excluded.Retrospective analysis was done in 126 eligible cases.Among them,64 patients received TIPS(TIPS group) while 62 patients received endoscopic therapy(ET group).The relevant data were collected by patient review or telephone calls.The occurrence of rebleeding,hepatic encephalopathy or other complications,survival rateand cost of treatment were compared between the two groups.RESULTS:During the follow-up period(median,20.7 and 18.7 mo in TIPS and ET groups,respectively),rebleeding from any source occurred in 11 patients in the TIPS group as compared with 31 patients in the ET group(Kaplan-Meier analysis and log-rank test,P = 0.000).Rebleeding rates at any time point(6 wk,1 year and 2 year) in the TIPS group were lower than in the ET group(Bonferroni correction α' = α/3).Eight patients in the TIPS group and 16 in the ET group died with the cumulative survival rates of 80.6% and 64.9%(Kaplan-Meier analysis and log-rank test c2 = 4.864,P = 0.02),respectively.There was no significant difference between the two groups with respect to 6-wk survival rates(Bonferroni correction α' = α/3).However,significant differences were observed between the two groups in the 1-year survival rates(92% and 79%) and the 2-year survival rates(89% and 64.9%)(Bonferroni correction α' = α/3).No significant differences were observed between the two treatment groups in the occurrence of hepatic encephalopathy(12 patients in TIPS group and 5 in ET group,KaplanMeier analysis and log-rank test,c2 = 3.103,P = 0.08).The average total cost for the TIPS group was higher than for ET group(Wilcxon-Mann Whitney test,52 678 RMB vs 38 844 RMB,P < 0.05),but hospitalization frequency and hospital stay during follow-up period were lower(Wilcxon-Mann Whitney test,0.4 d vs 1.3 d,P = 0.01;5 d vs 19 d,P < 0.05).CONCLUSION:Early use of TIPS is more effective than endoscopic treatment in preventing variceal rebleeding and improving survival rate,and does not increase occurrence of hepatic encephalopathy. | Hui Xue Meng Zhang Jack XQ Pang Fei Yan Ying-Chao Li Liang-Shan Lv Jia Yuan Muna Palikhe Wei-Zhi Li Zhi-Lun Wang | 2012 | World Journal of Gastroenterology2012，18，48： | 17 |
| 3 | 血清补体C3/C4比值是再发心血管事件的新指标 | Palikhe A. Sinisalo J. Seppnen M. M.-L. Lokki 罗亮 | 2007 | 世界核心医学期刊文摘(心脏病学分册)2007，0，8： | 2 |
| 4 | Serum complement C3/CA ratio, a novel marker for recurrent cardiovascular events显示文摘 | Palikhe A Sinisalo J Seppanen M | 2007 | Am J Cardi- ol2007，99，7： | 1 |
| 5 | Serum complement C3/C4 ratio,a novel marker for recurrent cardiovascular events显示文摘 | Palikhe A Sinisalo J Seppanen M | | 0，，07： | 1 |
| 6 | Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma 显示文摘 | Palikhe NS Kim SH Cho BY | 2008 | Respir Med2008，102，8： | 1 |
| 7 | Serum i-omplementC3/C4 ratio, a novel marker for recurrent cardiovascular events显示文摘 | Palikhe A Sinisalo J Seppnen M | 2007 | Am J Cardiol2007，99，7： | 1 |
| 8 | Efficacy of laparoseopic sleeve gastrectomy and intensive medical management in obese patients with type 2 diabetes meUitus 显示文摘 | Palikhe G Gupta R Behera BN | 2014 | Obes Surg2014，24，4： | 1 |
| 9 | Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma 显示文摘 | Palikhe NS Kim SH Cho BY | 2008 | Respir Med2008，102，8： | 1 |
| 10 | Genetic and ethnic risk factors associated with drug hypersensitivity 显示文摘 | Kim SH Ye YM Palikhe NS | 2010 | Curt Opin Allergy Clin Immunol2010，10，4： | 1 |
| 11 | Genetic and ethnic risk factors associated with drug hypersensitivity显示文摘 | Seung-Hyun Kim Young-Min Ye Nami Shrestha Palikhe Jeong-Eun Kim Hae-Sim Park | 2010 | Current Opinion in Allergy and Clinical Immunology2010，，4： | 1 |
| 12 | Genetic and ethnic risk factors associated with drug hypersensitivity显示文摘 | Kim SH Ye YM Palikhe NS etal | 2010 | Curr Opin Allergy Clin Immunol2010，10，4： | 1 |
| 13 | Association of thromboxane A2 receptor (TBXA2R) gene polymorphism in patients with aspirin- intolerant acute urticaria 显示文摘 | Palikhe NS Kim SH Lee HY | 2011 | Clin Exp Allergy2011，41，2： | 1 |
| 14 | Chlamydia pneumoniae DNA is present in peripheral blood mononu- clear cells during acutecoronary syndrome and correlates with chlamydial lipopolysaccharide levels in serum 显示文摘 | Palikhe A Tiirola T Puolakkainen M | 2009 | Scand J Infect Dis2009，41，3： | 1 |
| 15 | Serum complement C3/ C4 ratio an ovel marker for recurrent eardiovaseular events 显示文摘 | Palikhe A Sinisalo J Seppanen M | 2007 | Am J Cardiol2007，99，7： | 1 |
| 16 | Role of Toll-like Receptor 3 Variants in Aspirin-Exacerbated Respiratory Disease显示文摘 | Palikhe NS Kim SH Kim JH | 2011 | Allergy Asthma Immunol Res2011，3，2： | 1 |
| 17 | Serum complement C3/C4 ratio, a novol marker for recurrent cardiovascular e- vents显示文摘 | Palikhe A Sinisalo J Seppanen M | 2007 | Am J cardiol2007，99，7： | 1 |
| 18 | Genetic and ethnic riskfactors associated with drug hypersensitivity 显示文摘 | Kim SH Ye YM Palikhe NS | 2010 | Curr OpinAllergy Clin Immunol2010，10，4： | 1 |
| 19 | Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma 显示文摘 | Palikhe NS Kim SH Cho BY | 2008 | Respir Med2008，102，8： | 1 |
| 20 | Association of three sets of highaffinity Ig E receptor(Fcepsilon R1)polymorphisms with aspirin-intolerant asthma显示文摘 | Palikhe NS Kim SH Cho BY | 2008 | Respir Med2008，102，8： | 1 |
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