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| 1 | Vertical hepatitis C virus transmission:Main questions and answers显示文摘Hepatitis C virus(HCV) affects about 3% of the world's population and peaks in subjects aged over 40 years. Its prevalence in pregnant women is low(1%-2%) in most western countries but drastically increases in women in developing countries or with high risk behav-iors for blood-transmitted infections. Here we review clinical, prognostic and therapeutic aspects of HCV in-fection in pregnant women and their offspring infected through vertical transmission. Pregnancy-related im-mune weakness does not seem to affect the course of acute hepatitis C but can affect the progression of chronic hepatitis C. In fact, postpartum immune res-toration can exacerbate hepatic inflammation, thereby worsening the liver disease, particularly in patients with liver cirrhosis. HCV infection increases the risk of gestational diabetes in patients with excessive weight gain, premature rupture of membrane and caesarean delivery. Only 3%-5% of infants born to HCV-positive mothers have been infected by intrauterine or perinatal transmission. Maternal viral load, human immunode-ficiency virus coinfection, prolonged rupture of mem-branes, fetal exposure to maternal infected blood con-sequent to vaginal or perineal lacerations and invasive monitoring of fetus increase the risk of viral transmis-sion. Cesarean delivery and breastfeeding increases the transmission risk in HCV/human immunodeficiency virus coinfected women. The consensus is not to offer antivi-ral therapy to HCV-infected pregnant women because it is based on ribavirin(pregnancy category X) because of its embryocidal and teratogenic effects in animal spe-cies. In vertically infected children, chronic C hepatitis is often associated with minimal or mild liver disease and progression to liver cirrhosis and hepatocarcinoma is lower than in adults. Infected children may be treated after the second year of life, given the adverse effects of current antiviral agents. | Grazia Tosone Alberto Enrico Maraolo Silvia Mascolo Giulia Palmiero Orsola Tambaro Raffaele Orlando | 2014 | World Journal of Hepatology2014，6，8： | 5 |
| 2 | Kaposi's sarcoma occurring in a young black man after kidney transplantation显示文摘 | De Blasio A Palmiero G Russo D | 2005 | Nephrology Dialysis Transplantation2005，20，： | 1 |
| 3 | Bilateral Descemet mem- brane detachment after eanaloplasty显示文摘 | Palmiero PM Aktas Z Lee O | 2010 | J Cataract Refract Surg2010，36，3： | 1 |
| 4 | Noncontact in vivo confocal laser scanning microscopy of exfoliation syndrome显示文摘 | BY Zaher Sbeity Pat-Michael Palmiero Celso Tello | | 0，，： | 1 |
| 5 | Iris morphologic changes related to alpha(1)-adrenergic receptor antagonists im- plications for intraoperative floppy iris syndrome显示文摘 | Prata TS Palmiero PM Angelilli A et a| | | Ophthal- mology0，116，： | 1 |
| 6 | Testicular activity of Mos in the frog, Rana esculenta:a new role in spermatogonial proliferation显示文摘 | Ferrara D Palmiero C Branno M | 2004 | Biol Reprod2004，70，6： | 1 |
| 7 | Coronary artery calcifica- tion in patients with CRE not undergoing dialysis显示文摘 | Russo D Palmiero G De Biasio AP | 2004 | Am J Kidney Dis2004，44，6： | 1 |
| 8 | Comparisons of anterior segment biometry between Chinese and Caucasians using anterior segment optical coherence tomography显示文摘 | Leung CK Palmiero PM Weinreb RN | 2010 | Br J Ophthalmol2010，94，： | 1 |
| 9 | Effects of itraco_ nazole on tacrolimus blood concentrations in a renal tr_ ansplant recipient显示文摘 | Gentile A Imperatore P Palmiero G | 1999 | Ann Pharmacother1999，33，10： | 1 |
| 10 | Long-term assessment of plasma lipids in transpluit recipients treated with tacrolimus in re- lation to fatty liver显示文摘 | Tarantino G Palmiero G Polichetti G | 2010 | Int J Immunopathol Pharmacol2010，23，4： | 1 |
| 11 | New approaches in pul- monary rehabilitation显示文摘 | Ambrosino N Palmiero G Strambi SK | 2007 | Clin Chest Med2007，28，3： | 1 |
| 12 | Coronary artery calcifica- tion in patients with CRF not undergoing dialysis 显示文摘 | Russo D Palmiero G De Blasio AP | 2004 | Am J Kidney Dis2004，44，6： | 1 |
| 13 | Arrhythmie risk in essential hypertension: late potentials 显示文摘 | PALMIERO P MAIELLO M | 2004 | Minerva Cardioangiol2004，52，1： | 1 |
| 14 | A pharmacokinetic in- teraction between clarithromyein and sirolimus in kidney transplant recipient显示文摘 | Capone D Palmiero G Gentile A | 2007 | Curt Drug Metab2007，8，4： | 1 |
| 15 | Arrhythmic risk in essential hypertension:late potentials显示文摘 | Maiello M | 2004 | Minerva Cardioangiol2004，52，： | 1 |
| 16 | Ventricular arrythmias and left ventricular hypertrophy in essential hypertension显示文摘 | PALMIERO P MAIELL0 M | 2000 | Minerva Cardiongiol2000，48，12： | 1 |
| 17 | Iris morphologic changes related to alpha (1)-adrenergic receptor antagonists implications for intraoperative floppy iris syndrome显示文摘 | Prata TS Palmiero PM Angelilli A | 2009 | Ophthalmology2009，116，5： | 1 |
| 18 | Heart failure and diabetes:left ventricular systolic function显示文摘 | Palmiero R Macello M De Pascalis S | | 0，，02： | 1 |
| 19 | Arrhythmic risk in essential hypertension:late potentials显示文摘 | Palmiero P Maiello M | 2004 | Minerva Cardioangiol2004，52，： | 1 |
| 20 | Ventricular arrythmias and left ventricular hypertrophy in essential hypertension显示文摘 | Maiello M | 2000 | Minerva Cardiongiol2000，48，12： | 1 |
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