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| 1 | Pyogenic liver abscess:An audit of 10 years’experience显示文摘AIM:To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy.METHODS:A retrospective study of records of 63 PLA patients presenting between 1998 and 2008 to Australian tertiary referral centre,were reviewed.Amoebic and hydatid abscesses were excluded.Demographic,clinical,radiological,and microbiological characteristics,as well as surgical/radiological interventions,were recorded.RESULTS:Sixty-three patients(42 males,21 females) aged 65(±14) years[mean±(SD) ]had prodromal symptoms for a median(interquartile range;IQR) of 7(5-14) d.Only 59%of patients were febrile at presentation;however,the serum C-reactive protein was elevated in all 47 in whom it was measured.Liver function tests were non-specifically abnormal.67%of patients had a solitary abscess,while 32%had>3 abscesses with a median(IQR) diameter of 6.3(4-9) cm.Causative organisms were:Streptococcus milleri 25%,Klebsiella pneumoniae 21%,and Escherichia coli 16%.A presumptive cryptogenic cause was most common (34%).Four patients died in this series:one from sepsis,two from advanced cancer,and one from acute myocardial infarction.The initial procedure was radiological aspiration±drainage in 54 and surgery in two patients.17%underwent surgical management during their hospitalization.Serum hypoalbuminaemia[mean (95%CI) :32(29-35) g/L vs 28(25-31) g/L,P=0.045] on presentation was found to be the only factor related to failure of initial percutaneous therapy on univariate analysis.CONCLUSION:PLA is a diagnostic challenge,because the presentation of this condition is non-specific.Intravenous antibiotics and radiological drainage in the first instance allows resolution of most PLAs;However,a small proportion of patients still require surgical drainage. | Tony CY Pang Thomas Fung Jaswinder Samra Thomas J Hugh Ross C Smith | 2011 | World Journal of Gastroenterology2011，17，12： | 46 |
| 2 | Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels显示文摘 | Fu H Li W Lao Y Luo J Lee NT Kan KK Tsang HW Tsim KW Pang Y Li Z Chang DC Li M Han Y | 2006 | 中国生物学文摘2006，20，10： | 10 |
| 3 | Finite-dimensional variational inequalities and non-linear complementarity problems: a survey of theory, algorithms and applications显示文摘 | Harker P T Pang J S | 1990 | Mathematical Programming1990，48，2： | 2 |
| 4 | Genetic transformation of wheat mediated by Agrobacterium tumefaciens显示文摘 | Cheng M Fry J E Pang S Zhou H Hironaka C M Duncan D R Conner T W Wan Y | 1997 | Plant Physiol1997，，： | 2 |
| 5 | Chemical and pharmacological evaluation of Hypericum perforation extracts显示文摘KEY WORDS Hypericum perforation; High pressure liquid chromatography; serotonin uptake inhibitors; tree radicals; antioxidants; hyperforin; hypericin; quercetin; rutinABSTRACTAIM: To determine the concentrations of chemical characteristic to extracts of leaves and flowers of Hypericum perforatnm (St John’s wort) in a number of selected samples and, following chemical characterization, to investigate the effects of these extracts on several pharmacological properties including effects of the extracts on inhibition of 5-hydroxytryptamine (5-HT) uptake and on an-tioxidant properties. METHODS: The samples were analyzed for the presence of characteristic chemicals by high performance liquid chromatography (HPLC) directly coupled to ultraviolet wavelength absorbance and positive or negative mode electrospray mass spectrometric detection. The effects of extracts on 5-HT uptake were determined by quantifying 3H-5-HT incorporation into rat hip-pocampal prisms. Estimates of effects of extracts on free radical | B Duff SLOLEY Liana J URICHUK LING Lei GU Lie-Dong Ronald T COUTTS Peter K T PANG Jacqueline J SHAN | 2000 | Acta Pharmacologica Sinica2000，21，12： | 2 |
| 6 | Finite dimensional variational inequality and nonlinear complementarity problems:a survey of theory,algorithms and applications显示文摘 | Harker P T Pang J S | 1990 | Math Program1990，48，： | 2 |
| 7 | Asymmetric variational inequality problems over product sets:applications and iterative methods显示文摘 | Pang J S | 1985 | Math Programming1985，31，2： | 2 |
| 8 | Synthesis of UV-curable organicinorganic hybrid urethane acrylates and properties of cured films显示文摘 | Xu J Pang W Shi W | 2006 | Thin Solid Films2006，514，12： | 1 |
| 9 | Electroacupuneture attenuates both glutamate release and hyperemia after transient ischemia in gerbils显示文摘 | Pang J Itano T Sumitani K | 2003 | Am J Chin Med2003，31，2： | 1 |
| 10 | Isothermal and thermal cycling aging on IMC growth rate in lead-free and lead-based solder Interface显示文摘 | XU L H PANG J H L PRAKASH K H | 2005 | IEEE Transactions on Components and Packaging Technology2005，28，3： | 1 |
| 11 | Impact of monsoonal climatic change on Holocene overbank flooding along Sushui River, middle reach of the Yellow River, China 显示文摘 | Huang C C Pang J L Zha X C | 2007 | Quaternary Science Reviews2007，26，： | 1 |
| 12 | Expression profiling identifies new function of collapsin response mediator protein 4 as a metastasis- suppressor in prostate cancer 显示文摘 | Gao X Pang J Li L Y | 2010 | Oncogene2010，29，32： | 1 |
| 13 | The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance显示文摘 | Pagel-Langenickel I Bao J Pang L | 2010 | Endocr Rev2010，31，1： | 1 |
| 14 | Newton's method for a B-differentiableequations显示文摘 | Pang J S | 1990 | Math Opre Res1990，15，： | 1 |
| 15 | Cyclooxygenase(cox)inhibitors induce apoptosis in nonsmall cell lung cancer through cyclooxygenase independent pathways显示文摘 | Sanchez-Alcazar J A Bradbury D A Pang L | 2003 | Lung Cancer2003，40，1： | 1 |
| 16 | Atomic force microscopy investigat ion o f radiation-induced DNA double strand breaks显示文摘 | Pang D Popescu G Rodgers J | 1996 | Scanning Microscopy1996，10，4： | 1 |
| 17 | Strategic gaming analysis for electric power systems:an MPEC approach显示文摘 | Hobbs B F Metzler C B Pang J S | 2000 | IEEE Transactions on Power Systems2000，15，2： | 1 |
| 18 | Effect of temperature and strain rate on mechanical properties of 63Sn/37Pb solder alloy显示文摘 | Shi X Q Zhou W Pang H L J | 1999 | ASME:Journal of Electronic Packaging1999，121，： | 1 |
| 19 | A multiples RT-PCR for type A influenza virus and differentiation of avian H5 and H9 hemagglutinin subtypes显示文摘 | Xie Z Pang Y S Liu J | 2006 | Mol Cell Probes2006，20，34： | 1 |
| 20 | CD27 is a thymic determinant of the balance between interferon-γ- and interleukin-17-producing γδ T cell subsets显示文摘 | Ribot J C deBarros A Pang D J | 2009 | Nat Immunol2009，10，： | 1 |
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