|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The role of DJ-1 in the oxidative stress cell death cascade after stroke显示文摘Oxidative stress is closely associated with secondary cell death in many disorders of the central nervous system including stroke,Parkinson’s disease,Alzheimer’s disease.Among many aberrant oxidative stress-associated proteins,DJ-1 has been associated with the oxidative stress cell death cascade primarily in Parkinson’s disease.Although principally expressed in the cytoplasm and nucleus,DJ-1 can be secreted into the serum under pathological condition.Recently,a close pathological association between DJ-1 and oxidative stress in stroke has been implicated.To this end,we and others have demonstrated the important role of mitochondria in neuroprotection for stroke by demonstrating that the translocation of DJ-1 in the mitochondria could potentially mitigate mitochondrial injury.Here,we discuss our recent findings testing the hypothesis that DJ-1 not only functions as a form of intracellular protection from oxidative stress,but that it also utilizes paracrine and/or autocrine cues in order to accomplish extracellular signaling between neighboring neuronal cells,resulting in neuroprotection.This article highlights recent evidence supporting the status of DJ-1 as key anti-oxidative stress therapeutic target for stroke. | Paolina Pantcheva Maya Elias Kelsey Duncan Cesar V.Borlongan Naoki Tajiri Yuji Kaneko | 2014 | Neural Regeneration Research2014，9，15： | 5 |
| 2 | Drug-and cell-based therapies for targeting neuroinflammation in traumatic brain injury显示文摘TBI pathology:Traumatic brain injury(TBI)is caused by an external force to the head,resulting in trauma to the brain.Approximately 1.7 million Americans suffer from TBI every year.Out of the 1.7 million suffering from TBI,an estimated52,000 injuries result in death,leaving a mass amount of people with symptoms that could last a few days,a few years,or their entire life(Faul et al.,2010).TBI can be classified as mild,moderate and severe.Depending on the classification and | Sussannah Kaelber Paolina Pantcheva Cesar V.Borlongan | 2016 | Neural Regeneration Research2016，11，10： | 3 |
| 3 | Effects of agronomical measures on the microbial diversity of soils oasrelated to the suppression of soil- borne plant pathogens 显示文摘 | Jan Dirk van Etsas Paolina Garbeva Joana Salles | 2002 | Biodegradation2002，13，： | 1 |
| 4 | Effects of agronom- ical measures on the microbial diversity of soils as re-lated to the suppression of soil-borne plant pathogens 显示文摘 | Jan Dirk V E Paolina G Joana S | 2002 | Biodegradation2002，13，1： | 1 |
| 5 | Security and Privacy Frameworks for Access Control Big Data Systems显示文摘In the security and privacy fields,Access Control(AC)systems are viewed as the fundamental aspects of networking security mechanisms.Enforcing AC becomes even more challenging when researchers and data analysts have to analyze complex and distributed Big Data(BD)processing cluster frameworks,which are adopted to manage yottabyte of unstructured sensitive data.For instance,Big Data systems’privacy and security restrictions are most likely to failure due to the malformed AC policy configurations.Furthermore,BD systems were initially developed toped to take care of some of the DB issues to address BD challenges and many of these dealt with the“three Vs”(Velocity,Volume,and Variety)attributes,without planning security consideration,which are considered to be patch work.Some of the BD“three Vs”characteristics,such as distributed computing,fragment,redundant data and node-to node communication,each with its own security challenges,complicate even more the applicability of AC in BD.This paper gives an overview of the latest security and privacy challenges in BD AC systems.Furthermore,it analyzes and compares some of the latest AC research frameworks to reduce privacy and security issues in distributed BD systems,which very few enforce AC in a cost-effective and in a timely manner.Moreover,this work discusses some of the future research methodologies and improvements for BD AC systems.This study is valuable asset for Artificial Intelligence(AI)researchers,DB developers and DB analysts who need the latest AC security and privacy research perspective before using and/or improving a current BD AC framework. | Paolina Centonze | 2019 | Computers, Materials & Continua2019，，5： | 1 |
| 6 | Ef- fects of agronomical measures on the microbial diversity of soils as related to the suppression of soil borne plant pathogens 显示文摘 | VAN ELSAS Jan Dirk GARBEVA Paolina SALLES Joana | 2002 | Bio- degradation2002，13，： | 1 |
| 7 | Carbon blacks for lead-acid batteries in micro-hybrid applications – Studied by transmission electron microscopy and Raman spectroscopy显示文摘 | Ellen Ebner Daniel Burow Jana Panke Alexander B?rger Armin Feldhoff Paolina Atanassova Jesus Valenciano Michael Wark Eckart Rühl | 2013 | Journal of Power Sources2013，，： | 1 |
| 8 | Carbon blacks for the extension of the cycle life in flooded lead acid batteries for micro-hybrid applications显示文摘 | Ellen Ebner Daniel Burow Alexander B?rger Michael Wark Paolina Atanassova Jesús Valenciano | 2013 | Journal of Power Sources2013，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员