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| 1 | Protective effect of lycopene on lipid peroxidation and oxidative DNA damage in cell culture显示文摘 | Humberto RM Paolo DM Marisa HG | 2000 | Archives of Biochem Biophy2000，383，1： | 1 |
| 2 | Posteriorchamber phakic intraocular lens(ICL)for hyperopia:Ten-year fol-low-up显示文摘 | Paolo MP Maria PG Giuseppe DM Giordano Fanton | 2007 | Journal of Cataract & Refractive Surgery2007，33，9： | 1 |
| 3 | Recognition of vi- res infection and innate host responses to viral gene therapy vec- tors显示文摘 | Shayakhmetov DM DI Paolo NC Mossman KL | 2012 | Mol Ther2012，18，8： | 1 |
| 4 | Recognitionof virus infection and innate host responses to viral gene therapyvectors 显示文摘 | Shayakhmetov DM Di Paolo NC Mossman KL | 2010 | MolTher2010，18，8： | 1 |
| 5 | Carotenoids,tocopherols and thiols as biological single molecular oxygen quenchers显示文摘 | Paolo DM Devasagayam TPA | 1990 | Biochem Soc Trans1990，18，： | 1 |
| 6 | Autoimmune Diabetes not requiring insulin at diagnosis (latent autoimmune diabetes of the adult)显示文摘 | Paolo P Umberto DM | 2001 | Diabetes Care2001，24，8： | 1 |
| 7 | Redundant and synergistic mechanisms control the sequestration of blood-born adenovirus in the liver显示文摘 | Di Paolo NC van Rooijen N Shayakhmetov DM | | 0，，04： | 1 |
| 8 | Recognition of virus infection and innate host responses to viral gene therapy vee- tors 显示文摘 | Shayakhmetov DM DI Paolo NC Mossman KL | 2012 | Mol Ther2012，18，8： | 1 |
| 9 | Nonalcoholic fatty liver disease prevalence in an Italian cohort of patients with hidradenitis suppurativa: A multi-center retrospective analysis显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD) includes two distinct conditions, with different histologic features and prognosis: non-alcoholic fatty liver(NAFL) and non-alcoholic steatohepatitis(NASH). Furthermore, NASH is the more aggressive necro-inflammatory form, which may accumulate fibrosis and result in End stage liver disease(ESLD). NAFLD is also linked to systemic inflammatory conditions such as psoriasis. NAFLD is currently the most common cause of ESLD in Western countries, becoming a serious public health concern.Hidradenitis suppurativa(HS) is a systemic inflammatory/autoinflammatory disease of the terminal follicular epithelium of the apocrine gland with a prevalence of 0.05% to 4.10%. Due to its systemic inflammatory behavior several comorbidities were recently associated, however liver ones were scarcely assessed.AIM To evaluate the prevalence and characteristics of NASH/NAFL in HS patients.METHODS This retrospective study is a sub-analysis of a larger study carried out in 4 Italian dermatological centers. In this cohort, there were 83 patients: 51 patients with HS only, 20 patients with HS/NAFL and 12 with HS/NASH.RESULTS Inflammatory comorbidities were present in 3.9% of HS only patients, 25% of HS/NAFL patients and 58.3% of HS/NASH patients(P < 0.001). Similarly, mean Autoinflammatory Disease Damage Index(ADDI) was significantly higher among patients with HS/NASH(5.3 ± 2.2, P < 0.001) compared to patients with HS/NAFL or HS only(2.8 ± 1.6 and 2.6 ± 1.4 respectively). Furthermore, ADDI correlates with IHS4 in HS, HS/NAFL and HS/NASH. Diabetic patients have higher Hurley score than not diabetic ones. Ultrasound examination was significantly different in the three groups.CONCLUSION HS patients displayed a high prevalence of NASH/NAFLD and ultrasound examination should be particularly addressed to patients that display high ADDI scores. | Giovanni Damiani Sebastiano Leone Kristen Fajgenbaum Nicola L Bragazzi Alessia Pacifico Rosalynn RZ Conic Paolo DM Pigatto Carlo Maiorana Pierpaolo Poli Emilio Berti Maria C Pace Piergiorgio Malagoli Vincenzo Bettoli Marco Fiore | 2019 | World Journal of Hepatology2019，11，4： | 0 |
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