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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012,45,5: | 22 |
| 2 | 青年人群单纯收缩期或舒张期高血压的心血管病风险显示文摘根据2017年美国心脏病学院/美国心脏协会高血压指南定义,在1级高血压青年人群中,关于单纯收缩期高血压(isolated systolic hypertension,ISH)、单纯舒张期高血压(isolated diastolic hypertension,IDH)或收缩期和舒张期高血压(systolic and diastolic hypertension,SDH)相关的健康预后知之甚少。方法:在全国健康筛查数据库中. | 刘青(译) 刘莉(校) Lee H Yano Y Cho SMJ Park JH Park S Lloyd-Jones DM Kim HC | 2020 | 中华高血压杂志2020,28,8: | 3 |
| 3 | 心脏病及非心脏病患者降低舒张压的效果:收缩压干预试验结果分析显示文摘收缩压和舒张压低于何种阈值时心血管事件增多仍然不明确。应用收缩压干预试验(systolic blood pressure intervention trial,SPRINT)的数据,研究者评估了1519例心血管病患者和7574位非心血管病者的收缩压和舒张压与心血管事件之间的关系。 | 刘青 叶鹏 Khan NA Rabkin SW Zhao Y McAlister FA Park JE Guan M Chan S Humphries KH | 2018 | 中华高血压杂志2018,26,6: | 3 |
| 4 | 干骺端固定解剖型非骨水泥柄结合陶瓷对陶瓷全髋关节置换治疗30岁以下患者的临床结果显示文摘年轻患者全髋关节置换手术方式还存在争议。作者分析了96例(127髋)30岁以下患者采用干骺端固定解剖型非骨水泥柄结合陶瓷对陶瓷全髋关节置换的治疗结果。随访10~16年,Harris评分、WOMAC评分、UCLA评分分别为95、16、8分。手术1年后,没有发生疼痛,所有股骨柄均未发现松动。无关节异响、陶瓷碎裂、松动以及骨溶解等并发症。因此作者认为, | Kim Y H Park J W Kim J S 胡孔足 | 2012 | 临床骨科杂志2012,15,5: | 3 |
| 5 | Mimicking unfolding motion of a beetle hind wing显示文摘This paper presents an experimental research aiming to realize an artificial hind wing that can mimic the wing unfolding motion of Allomyrina dichotoma, an insect in coleopteran order. Based on the understanding of working principles of beetle wing folding/unfolding mechanisms, the hind wing unfolding motion is mimicked by a combination of creative ideas and state-of-art artificial muscle actuator. In this work, we devise two types of artificial wings and the successfully demonstrate that they can be unfolded by actuation of shape memory alloy wires to provide actuation force at the wing base and along the leading edge vein. The folding/unfolding mechanisms may provide an insight for portable nano/micro air vehicles with morphing wings. | MUHAMMAD Azhar PARK Hoon C HWANG Do Y BYUN Doyoung GOO Nam S | 2009 | Chinese Science Bulletin2009,54,14: | 3 |
| 6 | Solidification microstructure and M2C carbine decomposition in a spray-formed high-speed steel显示文摘 | Lee E Park W Jung J Y Ahn S | 1998 | Metallurgical and Materials Transactions A1998,29,: | 2 |
| 7 | Carbohydrate metabolism in the developing endosperm of rice grain显示文摘 | Nakamura Y Yuki K Park S Y | 1989 | Plant Cell Physiology1989,30,: | 2 |
| 8 | Calibration of a redundant IMU 显示文摘 | CHO S Y PARK C G | 2004 | AIAA Guidance navigation and Control Conference and Exhibit Providence Rhode Island AIAA2004,2004,: | 1 |
| 9 | The preparation of exfoliated graphite by using microwaves 显示文摘 | KWON O CHOIR S PARK K KWON Y | 2003 | J Ind Eng Chem (Seoul Republic Korea)2003,9,6: | 1 |
| 10 | 显示文摘 | Jung K Y Park S B | 1999 | J Photochem Photobiol A Chem1999,127,: | 1 |
| 11 | 3D welding and milling:Part I-a direct approach for freeform fabrication of metallic prototypes显示文摘 | Song Y A Park S Choi D | 2005 | International Journal of Machine Tools and Manufacture2005,45,9: | 1 |
| 12 | Kinetics of monodisperse iron oxide nanocrystal formation by “heating-up” process 显示文摘 | Kwon S G Piao Y Z Park J | 2007 | J Am Chem Soc2007,129,12: | 1 |
| 13 | Catalytic supercritical water oxidation of wastewater from terephthalie acid manufacturing process 显示文摘 | Park T J Lira J S Lee Y W | 2003 | The Journal of Supereritieal Fluids2003,26,3: | 1 |
| 14 | Antibody engineering for the development of therapeutic antibodies显示文摘 | Kim S J Park Y Hong H J | 2005 | Mol Cell2005,20,1: | 1 |
| 15 | Adaptive Hopfield neural network for economic load dispatch显示文摘 | Lee K W Y Yome A S Park J H | 1998 | IEEE Transactions on Power System1998,13,2: | 1 |
| 16 | 显示文摘 | Kweon D K Song S B Park Y Y | 2003 | Biomaterials2003,24,: | 1 |
| 17 | Free radical scavenging activities of different deacetylated chitosans using an ESR spectrometer显示文摘 | Park P J Je J Y Kim S W | 2004 | Carbohydrate Polymer2004,55,: | 1 |
| 18 | Calcium zinc borosilicate glass with high thermal expansion coefficient for LTCC Applications显示文摘 | PARK J S KIM Y SHIN H | 2008 | J Am Ceram Soc2008,91,11: | 1 |
| 19 | A scheduling method for network-based control systems 显示文摘 | Park H S Kim Y H Kim D S | 2002 | IEEE Transactions on Control Systems Technology2002,10,3: | 1 |
| 20 | Abscisic acid inhibits type 2C protein phosphatases via the PYR/ PYL family of START proteins显示文摘 | PARK S Y FUNG P NISHIMURA N JENSEN D R FFUJII ZHAO Y LUMBA S SANTIAGO J RODRIGUES A CHOW T F | 2009 | Science2009,324,: | 1 |