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    题名 作者 年代 出处 被引量
1Natural Variation in OsPRR37 Regulates Heading Date and Contributes to Rice Cultivation at a Wide Range of Latitudes显示文摘标题日期和光周期敏感是决定米饭改编到大量 geographicenvironments 的基本特点。由印射的量的特点地点(QTL ) 和候选人基因分析使用整个染色体重新定序,我们 foundthat Oryza sativa 伪反应 Regulator37 (OsPRR37;此后 PRR37 ) 为早 heading7-2 (EH7-2 ) 负责从迟了标题的米饭 Milyang23 (M23 ) 和早标题的米饭 H143 的一个十字被识别的 /Heading date2 (Hd2 ) QTL。在 CCT 的不变地保存的氨基酸的 H143 containsa 错误感觉变化(CONSTANS,共同喜欢,并且 TOC1 ) PRR37 protein.In 的领域世界米饭收集, nonfunctional PRR37 等位基因的不同类型在许多欧洲、亚洲的米饭栽培变种被发现。尤其是,在自然长天的条件下面极其早怀有 Ghd7/Hd4 和 PRR37/Hd2 花的 nonfunctional 等位基因的装饰用的梨树变化,并且被使适应米饭耕作的极北的区域,多达 53 ??  ? 攠潸祣瑳 ????? 楶牴 ??? 啅??Bon-Hyuk Koo Soo-Cheul Yoo Joon-Woo Park Choon-Tak Kwon Byoung-Doo Lee Gynheung An Zhanying Zhang linjie Li Zichao Li Nam-Chon Paek 2013Molecular Plant2013,6,6:42
2Tree-ring precipitation records from Baiyinaobao, Inner Mongolia since A.D. 1838显示文摘Correlation function analysis shows that total precipitation from April to early July (to July 10) in growing season limits the ring width of Picea Koraiensis significantly in Baiyinaobao, Xilinhot, Inner Mongolia. Thus a transfer function is designed to reconstruct the total precipitation from April to early July over the region for the last 160 years. The explained variance of the reconstruction is 49.3% (and 45.7% when adjusted for loss of degrees of freedom, N = 31, r = 0.702, F = 13.608, p < 0.0001). There are three relatively wet periods in the reconstruction which are: 1869—1875, 18861921 and 19431968, and four relatively dry periods: 1851—1868, 1876—1885, 1922—1943 and 1969—1999. Among them, the wet periods of 1886—1921 and 1943—1968, and the dry period of 1922—1943 appeared almost at the same time with those in Mt. Qilian region. Meanwhile, the dry period of 1922—1943 corresponds to high temperature and low rainfall during the 1920s and thereafter, and wetness of 1943—1968 corresponds very well to low temperature and more precipitation after the 1940s in Northwest, Northern China and the Changjiang River drainage basin. Calculation shows that the reconstruction series is significantly correlated with local dry-wet index (r = -0.234, p < 0.007, N = 143). Wavelet analysis indicates that there is a 22-a cycle in the precipitation of April to early July during 18381920, and an 11-a cycle during 1920—1952. No more cycles that reach 95% confidence limits are identified after 1953. The precipitation from April to early July quickly dropped into low during the 1920s. After 1950, precipitation shows a declining trend, but the reconstruction shows a tendency of increase in the late of 1990s.LIU Yu CAI Qiufang Park Won-Kyu AN Zhisheng MA Limin 2003Chinese Science Bulletin2003,48,11:29
3Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model显示文摘AIM To evaluate the anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium(DSS)-induced colitis model.METHODS An acute colitis mouse model was induced by oral administration of 5% DSS in the drinking water for 7 d. In the treated group, rosuvastatin(0.3 mg/kg per day) was administered orally before and after DSS administration for 21 d. On day 21, mice were sacrificed and the colons were removed for macroscopic examination, histology, and Western blot analysis. In the in vitro study, IEC-6 cells were stimulated with50 ng/m L tumor necrosis factor(TNF)-α and then treated with or without rosuvastatin(2 μmol/L). The levels of reactive oxygen species(ROS), inflammatory mediators, and apoptotic markers were measured. RESULTS In DSS-induced colitis mice, rosuvastatin treatment significantly reduced the disease activity index and histological damage score compared to untreated mice(P < 0.05). Rosuvastatin also attenuated the DSSinduced increase of 8-hydroxy-2'-deoxyguanosine and NADPH oxidase-1 expression in colon tissue. Multiplex ELISA analysis revealed that rosuvastatin treatment reduced the DSS-induced increase of serum IL-2, IL-4, IL-5, IL-6, IL-12 and IL-17, and G-CSF levels. The increased levels of cleaved caspase-3, caspase-7, and poly(ADP-ribose) polymerase in the DSS group were attenuated by rosuvastatin treatment. In vitro, rosuvastatin significantly reduced the production of ROS, inflammatory mediators and apoptotic markers in TNF-α-treated IEC-6 cells(P < 0.05).CONCLUSION Rosuvastatin had the antioxidant, anti-inflammatory and anti-apoptotic effects in DSS-induced colitis model. Therefore, it might be a candidate anti-inflammatory drug in patients with inflammatory bowel disease.Seung Kak Shin Jae Hee Cho Eui Joo Kim Eun-Kyung Kim Dong Kyun Park Kwang An Kwon Jun-Won Chung Kyoung Oh Kim Yoon Jae Kim 2017World Journal of Gastroenterology2017,23,25:11
4Endoscopic features suggesting gastric cancer in biopsy-proven gastric adenoma with high-grade neoplasia显示文摘AIM:To elucidate the endoscopic features that predict the cancer following endoscopic submucosal dissection(ESD)in patients with high-grade neoplasia(HGN).METHODS:We retrospectively analyzed the medical records of patients who underwent ESD of gastric neoplasms from January 2007 to September 2010.ESD was performed in 555 cases involving 550 patients.A total of 112 lesions from 110 consecutive patients were initially diagnosed as HGN without cancer by forceps biopsy,and later underwent ESD.We classified lesions into two groups according to histologic discrepancies between the biopsy and ESD diagnosis.Gastric adenoma in the final diagnosis by ESD specimens were defined as adenoma group.Lesions with coexisting cancer after ESD were defined as cancer group.RESULTS:The mean age was 65.3 years,and 81 patients were male.There was no significant difference in the age or gender distribution between the adenoma(n=52)and cancer(n=60)groups.Thirty-six of these lesions(32.1%)showed histologic concordance between the forceps biopsy and ESD specimens,16(14.3%)showed a downgraded histology(low-grade neoplasia),and 60(53.6%)showed an upgraded histology(cancer).A red color change of the mucosal surface on endoscopy was found in 27/52(51.9%)of cases in the adenoma group and in 46/60(76.7%)of cases in the cancer group(P=0.006).Ulceration of the mucosal surface on endoscopy was found in 5(9.6%)of 52 lesions in the adenoma group and in 17(28.3%)of 60 lesions in the cancer group(P=0.013).In the multivariate analysis,a reddish surface color change and mucosal ulceration were significant predictive factors correlated with cancer after ESD of the HGN by forceps biopsy.CONCLUSION:HGN with a red color change or mucosal ulceration correlated with the presence of gastric cancer.These finding may help to guide the diagnosis and treatment.Jung Ho Kim Yoon Jae Kim Jungsuk An Jong Joon Lee Jae Hee Cho Kyoung Oh Kim Jun-Won Chung Kwang An Kwon Dong Kyun Park Ju Hyun Kim 2014World Journal of Gastroenterology2014,20,34:10
5干扰素调节因子5通过损伤胞葬作用控制动脉粥样硬化病变中的坏死核心形成显示文摘髓系细胞是动脉粥样硬化病变发展和易损斑块形成的核心。动脉吞噬细胞吸收凋亡细胞(胞葬作用)的能力受损,可促进病变生长并建立坏死核心。干扰素调节因子(interferon regulatory factor,IRF)5是髓系细胞功能的重要调节因子。该研究试图确定IRF5是否影响动脉粥样硬化病变的形成和表型。方法:通过两种互补模型,研究IRF5在动脉粥样硬化中的作用:Seneviratne AN Edsfeldt AO Cole JE Kassiteridi C Swart M Park I Green P Khoyratty TE Saliba DG Goddard ME Sansom SN Goncalves I Krams R Udalova IA Monaco C 刘莉 叶鹏 2017中华高血压杂志2017,25,8:9
6An Early Cretaceous Avialian Bird, Shenzhouraptor sinensis from Western Liaoning, China显示文摘This paper describes an avialian bird from the Early Cretaceous Jiufotang Formation in Yixian county,western Liaoning, China, which is named as Shenzhouraptor sinensis by Ji et al. on July 15, 2002. Shenzhouraptor sinensis is characterized by no teeth in its mouth, the forelimbs longer than the hindlimbs, a long tail with more than 23 caudal vertebrae, U-shaped wishbone, and remiges longer than the total length of ulna and manus. It is certain that the new avialian bird is really capable of powerful flight, representing a missing link between theropod dinosaurs and birds.Ji Qiang, Ji Shu’an, You Hailu, Zhang Jianping,Zhang Hongbin, Zhang Nanjun, Yuan Chongxi and Ji XinxinDepartment of Earth Sciences, Nanjing University, Nanjing, Jiangsu 100093Institute of Geology, Chinese Academy of Geological Sciences, Beijing 100037 School of Earth and Space Sciences, Peking University, Beijing 100871China University of Geosciences, Beijing 100083 China Dinosaur Park of Changzhou, Changzhou, Jiangsu 213002 2003Acta Geologica Sinica(English Edition)2003,77,1:8
7Allele-specific PCR genotyping of the HSP70 gene polymorphism discriminating the green and red color variants sea cucumber (Apostichopus japonicus)显示文摘颜色变化是海黄瓜(Apostichopus japonicus ) 的一个著名特征,它基于他们红,绿色和黑色的颜色被分类进三个组。它也是他们味道怎么样的最重要的特点之一,并且它从而影响他们的市场价格。被尝试识别单个核苷酸的多型性(SNP ) 并且分析作为目标基因用 HSP70 与在绿、红的颜色变体之间的 SNP 遗传型联系的差别。HSP70 基因,从细菌在有机体普遍被发现到人,是最 evolutionarily 保存的基因和压力反应的最广泛地学习的 biomarker 之一。盖住海黄瓜 HSP70 基因的一个部分序列的 1074 bp 的 DNA 碎片,从红、绿的变体被放大,并且随后为 SNP 的存在分析了。包括异质接合的地点,总共的 27 个多态的地点被观察。这些,六个地点被发现是在绿、红的变体之间的显著地不同的 SNP 遗传型。而且,有设计在 3 结束(地点 443 ) 包括等位基因特定的 SNP 的一份内部教材的 PCR 分别地在绿、红的变体显示出在二变体, 100% 和 4.2% 扩大之间的区别。验证 SNP 可以用作能被用来在早发展的阶段区分变体的增进知识的基因标记,在颜色区别以前。Jung-Ha Kang Ki Hwan Yu Jung-Youn Park Chul-Min An Je-Cheon Jun Sang-Jun Lee 2011Journal of Genetics and Genomics2011,38,8:6
8Surgical failure after colonic stenting as a bridge to surgery显示文摘AIM: To identify risk factors for surgical failure after colonic stenting as a bridge to surgery in left-sided malignant colonic obstruction.METHODS: The medical records of patients who underwent stent insertion for malignant colonic obstruction between February 2004 and August 2012 were retrospectively reviewed. Patients with malignant colonic obstruction had overt clinical symptoms and signs of obstruction. Malignant colonic obstruction was diagnosed by computed tomography and colonoscopy. A total of 181 patients underwent stent insertion during the study period; of these, 68 consecutive patientswere included in our study when they had undergone stent placement as a bridge to surgery in acute leftsided malignant colonic obstruction due to primary colon cancer.RESULTS: Out of 68 patients, forty-eight(70.6%) were male, and the mean age was 64.9(range, 38-89) years. The technical and clinical success rates were 97.1%(66/68) and 88.2%(60/68), respectively. Overall, 85.3%(58/68) of patients underwent primary tumor resection and primary anastomosis. Surgically successful preoperative colonic stenting was achieved in 77.9%(53/68). The mean duration, defined as the time between the SEMS attempt and surgery, was 11.3 d(range, 0-26 d). The mean hospital stay after surgery was 12.5 d(range, 6-55 d). On multivariate analysis, the use of multiple self-expanding metal stents(OR = 28.872; 95%CI: 1.939-429.956, P = 0.015) was a significant independent risk factor for surgical failure of preoperative stenting as a bridge to surgery. Morbidity and mortality rates in surgery after stent insertion were 4.4%(3/68) and 1.5%(1/68), respectively.CONCLUSION: The use of multiple self-expanding metal stents appears to be a risk factor for surgical failure.Jung Ho Kim Kwang An Kwon Jong Joon Lee Won-Suk Lee Jeong-Heum Baek Yoon Jae Kim Jun-Won Chung Kyoung Oh Kim Dong Kyun Park Ju Hyun Kim 2014World Journal of Gastroenterology2014,20,33:5
9Backward Propagation of Otoacoustic Emissions显示文摘Normal mammalian ears not only detect but also generate sounds. The ear-generated sounds, i.e., otoacoustic emissions (OAEs), can be measured in the external ear canal using a tiny sensitive microphone. In spite of wide applications of OAEs in diagnosis of hearing disorders and in studies of cochlear functions, the question of how the cochlea emits sounds remains unclear. The current dominating theory is that the OAE reaches the cochlear base through a backward traveling wave. However, recently published works, including experimental data on the spatial pattern of basilar membrane vibrations at the emission frequency, demonstrated only forward traveling waves and no signs of backward traveling waves. These new findings indicate that the cochlea emits sounds through cochlear fluids as compression waves rather than through the basilar membrane as backward traveling waves. This article reviews different mechanisms of the backward propagation of OAEs and summarizes recent experimental results.HE Wenxuan,1, 2 REN Tianying,1, 21. Oregon Hearing Research Center, Department of Otolaryngology and Head & Neck Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, NRC04, Portland, Oregon 97239 USA 2. School of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi 710061 China 2006Journal of Otology2006,1,1:4
10Multicenter Prospective Comparative Study of Robotic Versus Laparoscopic Gastrectomy for Gastric Adenocarcinoma显示文摘Hyoung-Il Kim Sang-Uk Han Han-Kwang Yang Young-Woo Kim Hyuk-Joon Lee Keun Won Ryu Joong-Min Park Ji Yeong An Min-Chan Kim Sungsoo Park Kyo Young Song Sung Jin Oh Seong-Ho Kong Byoung Jo Suh Dae Hyun Yang Tae Kyung Ha Youn Nam Kim Woo Jin Hyung 2016Annals of Surgery2016,,1:4
11CO2/CH4 separation using inside coated thin film composite hollow fiber membranes prepared by interfacial polymerization显示文摘Carbon dioxide(CO_2) is greenhouse gas which originates primarily as a main combustion product of biogas and landfill gas. To separate this gas, an inside coated thin film composite(TFC) hollow fiber membrane was developed by interfacial polymerization between 1,3–cyclohexanebis–methylamine(CHMA) and trimesoyl chloride(TMC). ATR-FTIR, SEM and AFM were used to characterize the active thin layer formed inside the PSf hollow fiber. The separation behavior of the CHMA-TMC/PSf membrane was scrutinized by studying various effects like feed gas pressure and temperature. Furthermore, the influence of CHMA concentration and TMC concentration on membrane morphology and performance were investigated. As a result, it was found that mutually the CHMA concentration and TMC concentration play key roles in determining membrane morphology and performance. Moreover, the CHMA-TMC/PSf composite membrane showed good CO_2/CH_4 separation performance. For CO_2/CH_4 mixture gas(30/70 by volume) test, the membrane(PD1 prepared by CHMA 1.0% and TMC 0.5%) showed a CO_2 permeance of 25 GPU and the best CO_2/CH_4 selectivity of 28 at stage cut of 0.1. The high CO_2/CH_4 separation performance of CHMA-TMC/PSf thin film composite membrane was mostly accredited to the thin film thickness and the properties of binary amino groups.Eun-Sung Jo Xinghai An Pravin G.Ingole Won-Kil Choi Yeong-Sung Park Hyung-Keun Lee 2017Chinese Journal of Chemical Engineering2017,25,3:4
12Endoscopic stenting for recurrence-related colorectal anastomotic site obstruction:Preliminary experience显示文摘AIM:To evaluate the efficacy of stents in treating patients with anastomotic site obstructions due to cancer recurrence following colorectal surgery.METHODS:The medical records of patients who underwent endoscopic self-expanding metal stents(SEMS)insertion for colorectal obstructions between February2004 and January 2014 were retrospectively reviewed.During the study period,a total of 218 patients underwent endoscopic stenting for colorectal obstructions.We identified and examined the patients who underwent endoscopic stenting for obstructions caused by cancer recurrence at the anastomotic site following colorectal surgeries for primary colorectal cancer.RESULTS:Five consecutive patients[mean age,56.4years(range:39-82 years);4 women,1 man]underwent endoscopic stenting for obstructions caused by cancer recurrence at the anastomotic site following colorectal surgeries for primary colorectal cancer.Technical and clinical success was achieved in all 5 patients,without any early complications.During follow-up,3patients did not need further intervention,prior to their death,after the first stent insertion;thus,the overall success rate was 3/5(60%).Perforations occurred in 2patients who required a second SEMS insertion due to re-obstruction;none of the patients experienced stent migration.CONCLUSION:SEMS placement is a promising treatment option for patients who develop obstructions of their colonic anastomosis sites due to cancer recurrence.Jung Ho Kim Jong Joon Lee Jae Hee Cho Kyoung Oh Kim Jun-Won Chung Yoon Jae Kim Kwang An Kwon Dong Kyun Park Ju Hyun Kim 2014World Journal of Gastroenterology2014,20,38:4
13Akt is negatively regulated by the MULAN E3 ligase显示文摘serine/threonine kinase Akt 在多重细胞的进程工作,包括房间幸存和肿瘤开发。否定地调整 Akt 的机制的研究集中了于调停 dephosphorylation 的 inactivation。在这研究,我们识别了 Akt 的一个否定管理者, MULAN,它拥有一个戒指手指领域和 E3 ubiquitin ligase 活动。Akt 被发现直接与 MULAN 交往并且是由在 vitro 并且在 vivo 的 MULAN 的 ubiquitinated。另外的分子的试金证明 phosphorylated Akt 由 MULAN 是为和 MULAN 和 ubiquitination 的相互作用的一个真实目标。功能的研究的结果建议由 MULAN 的 Akt 的降级压制房间增长和生存能力。这些数据提供卓见进 Akt ubiquitination 发信号网络。Seunghee Bae Sun-Yong Kim Jin Hyuk Jung Yeongmin Yoon Hwa Jun Cha Hyunjin Lee Karam Kim Jongran Kim In-Sook An Jongdoo Kim Hong-Duck Um In-Chul Park Su-Jae Lee Seon Young Nam Young-Woo Jin Jae Ho Lee Sungkwan An 2012Cell Research2012,22,5:3
14Risk factors for tuberculosis after gastrectomy in gastric cancer显示文摘AIM: To examine incidence of tuberculosis(TB) in gastrectomy patients and investigate the risk factors for developing TB after gastrectomy in patients with gastric cancer.METHODS: A retrospective cohort study of gastrectomy patients with gastric cancer was performed at a university-affiliated hospital in Seoul, South Korea between January 2007 and December 2009. We reviewed patient medical records and collected data associated with the risk of TB, surgery, and gastric cancer. Standardized incidence ratios(SIRs) of TB were calculated to compare the incidence of TB in gastrectomy patients with that in the general Korean population, and risk factors for TB after gastrectomies were analyzed.RESULTS: Among the 1776 gastrectomy patients, 0.9%(16/1776) developed post-gastrectomy TB, with an incidence of 223.7 cases per 100000 patients per year. The overall incidence of TB in gastrectomy patients, adjusted by sex and age, was significantly higher thanthat in the general population(SIR = 2.22, 95%CI: 1.27-3.60). Previous TB infection [odds ratio(OR) = 7.1, P < 0.001], lower body mass index(BMI)(kg/m2; OR = 1.21, P = 0.043) and gastrectomy extent(total gastrectomy vs subtotal gastrectomy)(OR = 3.48, P = 0.017) were significant risk factors for TB after gastrectomy in a multivariate analysis.CONCLUSION: TB incidence after gastrectomy is higher than that in the general population. Previous TB infection, lower BMI, and total gastrectomy are risk factors for TB after gastrectomy in patients with gastric cancer.Won Jai Jung Young Mok Park Joo Han Song Kyung Soo Chung Song Yee Kim Eun Young Kim Ji Ye Jung Moo Suk Park Young Sam Kim Se Kyu Kim Joon Chang Sung Hoon Noh Ji Yeong An Young Ae Kang 2016World Journal of Gastroenterology2016,22,8:3
15Genome-Wide Identification and Validation of a Novel Methylation Biomarker, SDC2 , for Blood-Based Detection of Colorectal Cancer显示文摘TaeJeong Oh Nayoung Kim Youngho Moon Myung Soon Kim Benjamin D. Hoehn Chan Hee Park Tae Soo Kim Nam Kyu Kim Hyun Cheol Chung Sungwhan An 2013The Journal of Molecular Diagnostics2013,,4:2
16Comparison of litterfall production in three forest types in Jeju Island, South Korea显示文摘Litterfall, which is influenced by physical and biological factors, is a major pathway for carbon and nutrient cycling in forest ecosystems. The purpose of this study was to investigate monthly litterfall production in three forests in Jeju Island differentiated by forest composition and precipitation: Cheongsu(Quercus glauca as the dominant species;low precipitation), Seonheulb(Q. glauca as the dominant species;high precipitation), and Seonheulm(Q. glauca and Pinus thunbergii as the dominant species;high precipitation). Litterfall was collected monthly from April to December 2015 and divided into leaf litter, twig, bark, seeds, and unidentified materials.Seasonal patterns of litterfall production varied across stands according to their species composition. However,the amount of leaf litterfall and total litterfall were comparable among stands, ranging from 362 to 375 g m-2 for leaf litter and 524 g m-2 to 580 g m-2 for total litterfall.Oak leaf litter in May was the highest in all stands, while needle litter was the highest in December in Seonheulm.High twig litterfall in July may be attributable to high rainfall with strong winds and storms during the rainy season. Although forest type and climate factor had no influence on litterfall amounts in this study, the pattern of litterfall production was species dependent, suggesting diverse effects on carbon and nutrient cycling in these forests.Ji Young An Si Ho Han Woo Bin Youn Sang Ick Lee Afroja Rahman Huong Thi Thuy Dao Jeong Min Seo Aung Aung Hyung-Soon Choi Hwa Ja Hyun Byung Bae Park 2020Journal of Forestry Research2020,31,3:2
17Growth-promoting activity of Hominis Placenta extract on regenerating sciatic nerve显示文摘瞄准:Hominis 胎盘(HP ) 的摘录作为一个代理人在东方药被使用了改进生理的功能。现在的学习被进行调查在一个试验性的臀部的神经损害动物模型的 HP 处理是否在在损害以后改革周围神经纤维上生产支持生长的效果。方法:在 HP 被注入一个臀部的神经损害地点以后,在蛋白质层次的变化被西方的弄污和染色分析的免疫荧光在再生神经区域分析。为对轴索新生的量的评价,一种后退的跟踪技术被用来识别相应于改革轴突的神经元细胞体,并且在有教养的背侧根的神经突长出的程度轧了感觉神经元从经历了一处臀部的神经挤压伤的动物准备了的神经胶质( DRG )在神经原收集前的 7 d 被分析。结果:在受伤臀部的神经的轴索的联系生长的蛋白质(GAP-43 ) 的正式就职层次被 HP 处理提高。HP 处理(Cdc2 ) 也,在调整两极分裂周期 2 上面,蛋白质在受伤臀部的神经的远侧的树桩铺平。导致的 Cdc2 蛋白质在 Schwann 房间被检测,建议那项 Cdc2 激酶活动可以涉及改革经由 Schwann 房间增长的轴突的支持生长的活动。由后退的跟踪的房间身体测量显示 HP 治疗在改革马达轴突产生了重要增加。最后,有教养的 DRG 感觉神经元的 HP 处理显著地增加了神经突树枝状和延伸。结论:HP 支持受伤臀部的轴突的新生由在调整象 GAP-43 和 Cdc2 那样的新生相关的蛋白质因素的合成上面。Tae-beom SEO In-sun HAN Jin-hwan YOON In-chan SEOL Yun-sik RIM Hyun-kyung JO Joung-jo AN Kwon-eui HONG Young-bae SEO Dong-hee KIM Seung-kiel PARK Deok-chun YANG Uk NAMGUNG 2006Acta Pharmacologica Sinica2006,27,1:2
18Wireless phototherapeutic contact lenses and glasses with red light-emitting diodes显示文摘Light-mediated therapeutics have attracted considerable attention as a method for the treatment of ophthalmologic diseases,such as age-related macular degeneration,because of their non-invasiveness and the effectiveness to ameliorate the oxidative stress of retinal cells.However,the current phototherapeutic devices are opaque,bulky,and tethered forms,so they are not feasible for use in continuous treatment during the patient’s daily life.Herein,we report wireless,wearable phototherapeutic devices with red light-emitting diodes for continuous treatments.Red light-emitting diodes were formed to be conformal to three-dimensional surfaces of glasses and contact lenses.Furthermore,fabricated light-emitting diodes had either transparency or a miniaturized size so that the user’s view is not obstructed.Also,these devices were operated wirelessly with control of the light intensity.In addition,in-vitro and in-vivo tests using human retinal epithelial cells and a live rabbit demonstrated the effectiveness and reliable operation as phototherapeutic devices.Young-Geun Park Eunkyung Cha Hyeon Seok An Kyoung-Pil Lee Myoung Hoon Song Hong Kyun Kim Jang-Ung Park 2020Nano Research2020,13,5:2
19Micropapillary Carcinoma of Stomach: A Clinicopathologic and Immunohistochemical Study of 11 Cases显示文摘Ji Hyeon Roh Amitabh Srivastava Gregory Y. Lauwers Jungsuk An Kee-Taek Jang Cheol Keun Park Tae Sung Sohn Sung Kim Kyoung-Mee Kim 2010The American Journal of Surgical Pathology2010,,8:2
20The effect of texture on ridging of ferritic stainless steel显示文摘Hyung-Joon Shin Joong-Kyu An Soo Ho Park Dong Nyung Lee 2003Acta Materialia2003,,16:2
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