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| 1 | Aggressive behaviour of solid-pseudopapillary tumor of the pancreas in adults:A case report and review of the literature显示文摘Solid-pseudopapillary tumor (SPT) is a rare neoplasm of the pancreas that usually occurs in young females. It is generally considered a low-grade malignant tumor that can remain asymptomatic for several years. The occurrence of infiltrating varieties of SPT is around 10%-15%. Between 1986 and 2006, 282 cystic tumors of the pancreas were observed. Among them a SPT was diagnosed in 8 patients (2.8%) with only one infiltrating variety. This was diagnosed in a 49-year-old female 13 years after the sonographic evidence of a small pancreatic cystic lesion interpreted as a pseudocyst. The tumor invaded a long segment of the portal- mesenteric vein confluence, and was removed with a total pancreatectomy, resection of the portal vein and reconstruction with the internal jugular vein. Histological examination confirmed the R-0 resection of the primary SPT, although a vascular invasion was demonstrated. The postoperative course was uneventful, but 32 mo after surgery the patient experienced diffuse liver metastases. Chemotherapy with different drugs was started. The patient is alive and symptom-free, with stable disease, 75 mo after surgery. Twenty-five patients with invasion of the portal vein and/or of mesenteric vessels were retrieved from the literature, 16 recent patients with tumor relapse after potentially curative resection were also retrieved. The best treatment remains a radical resection whenever possible, even in locally advanced or metastatic disease. The role of chemotherapy, and/or radiotherapy, is still to be defined. | Cosimo Sperti Mattia Berselli Claudio Pasquali Davide Pastorelli Sergio Pedrazzoli | 2008 | World Journal of Gastroenterology2008，14，6： | 44 |
| 2 | Transcriptome analyses of the Dof-like gene family in grapevine reveal its involvement in berry, flower and seed development显示文摘The Dof(DNA-binding with one finger)protein family spans a group of plant transcription factors involved in the regulation of several functions,such as plant responses to stress,hormones and light,phytochrome signaling and seed germination.Here we describe the Dof-like gene family in grapevine(Vitis vinifera L.),which consists of 25 genes coding for Dof.An extensive in silico characterization of the VviDofL gene family was performed.Additionally,the expression of the entire gene family was assessed in 54 grapevine tissues and organs using an integrated approach with microarray(cv Corvina)and real-time PCR(cv Pinot Noir)analyses.The phylogenetic analysis comparing grapevine sequences with those of Arabidopsis,tomato,poplar and already described Dof genes in other species allowed us to identify several duplicated genes.The diversification of grapevine DofL genes during evolution likely resulted in a broader range of biological roles.Furthermore,distinct expression patterns were identified between samples analyzed,corroborating such hypothesis.Our expression results indicate that several VviDofL genes perform their functional roles mainly during flower,berry and seed development,highlighting their importance for grapevine growth and production.The identification of similar expression profiles between both approaches strongly suggests that these genes have important regulatory roles that are evolutionally conserved between grapevine cvs Corvina and Pinot Noir. | Danielle Costenaro da Silva Vítor da Silveira Falavigna Marianna Fasoli Vanessa Buffon Diogo Denardi Porto Georgios Joannis Pappas Jr Mario Pezzotti Giancarlo Pasquali Luís Fernando Revers | 2016 | Horticulture Research2016，3，1： | 5 |
| 3 | 克氏综合征患者的睾丸实质异常:一个有关肿瘤的问题?40例连续患者的研究显示文摘克氏综合征(Ks)是一种以染色体核型47,XXY为特征的高促性腺激素性腺功能减退症。一般而言,KS患者患睾丸肿瘤的风险与睾丸肿瘤的病因学理论是相关的;尽管其风险似乎是低下的。我们评估了对KS患者通过影像学检查以及血清肿瘤标记物检测进行睾丸肿瘤筛查的必要性。从2009年12月至2013年1月,共有40名KS患者参与了此项研究。在研究开始阶段、6个月以及随后每年对患者的血清乳酸脱氢酶(LDHl,甲胎蛋白(AFP)以及人绒毛膜促性腺激素B亚单位(beta-hCG)水平进行测定,并行睾丸彩色多普勒超声检查。当睾丸超声提示微钙化、睾丸结节以及囊肿时行腹部磁共振检查。62%的患者有规则的睾丸回声,37.5%出现不规则回声,17.5%有微钙化和囊肿。87%出现规则的血管结构,12.5%有精索静脉曲张,12.5%的患者结节〈1cm,但无患者结节大于1cm。磁共振检查排除了所有伴睾丸微钙化、结节和囊肿的患者忠睾丸肿瘤的可能性。随访未发现乳酸脱氢酶、甲胎蛋白、人绒毛膜促性腺激素B亚单位水平以及超声特征的显著改变。我们比较了有隐睾和无隐睾的克氏综合症患者血清肿瘤标记物水平以及其超声特征,发现并无统计学差异。研究未在KS患者中发现睾丸肿瘤,同时,在选定的患者中,睾丸超声、肿瘤标记物以及磁共振并不是鉴别良恶性病变的有效手段。 | Giacomo Accardo Gianfranco Vallone Daniela Esposito Filomena Barbato Andrea Renzullo Giovanni Conzo Giovanni Docimo Katherine Esposito Daniela Pasquali | 2015 | Asian Journal of Andrology2015，17，1： | 2 |
| 4 | The impact of obesity onreproduction in women with polycystic ovary syndrome显示文摘 | Pasquali R Gambineri A Pagotto U | 2006 | BJOG2006，113，10： | 1 |
| 5 | Preparative two-dimensional gel electrophoresis of membrane proteins显示文摘 | Pasquali C Fialka l Huber LA | 1997 | Electrophoresis1997，18，14： | 1 |
| 6 | Small particle-size lithium-vanadium oxide: an improved cathode material for high rate rechargeable lithium batteries 显示文摘 | Pistoia G Pasquali M Geronov Y | 1989 | J Power Sources1989，27，1： | 1 |
| 7 | PCOS forum: re- search in polycystic ovary syndrome today and tomorrow 显示文摘 | Pasquali R Stener-Vietorin E Yildiz BO | 2011 | Clin Endocrinol(Oxf)2011，74，4： | 1 |
| 8 | From pro- teins to proteomes:large scale protein identiWcation by two-dimensional electrophoresis and amino acid analysis 显示文摘 | Wilkins M R Pasquali C Appel R D | 1996 | Biotechnology (NY)1996，，14： | 1 |
| 9 | The role of low grade inflammation in the polycystic ovary syndrome显示文摘 | REPACI A GAMBINEKI A PASQUALI R | 2011 | Mol cell Endocrinol2011，335，1： | 1 |
| 10 | Pharmacological res- cue of caruitine transport in primary earnitine deficiency 显示文摘 | Di san Filippo CA Pasquali M Longo N | 2006 | Hum Mutat2006，27，： | 1 |
| 11 | Median pancreatectomy for tumors of the neck and body of the pancreas 显示文摘 | Sperti C Pasquali C Feronartor A | 2000 | J Am Coil Surg2000，190，6： | 1 |
| 12 | Obesity, fat distribution and infertility 显示文摘 | Pasquali R | 2006 | Maturitas2006，54，4： | 1 |
| 13 | A new synthetic route for preparing LiFePO4 with enhanced electrochemical performance显示文摘 | PROSINI P P CAREWSKA M SCACCIA S WISNIEWSKI P PASSERINI S PASQUALI M | 2002 | Journal of the Electrochemical Society2002，149，7： | 1 |
| 14 | Obesity and androgens: facts and perspectives 显示文摘 | Pasquali R | 2006 | Fertil Steril2006，85，5： | 1 |
| 15 | Two rapid and sensitive automated methods for the determination of nitrite and nitrate in soil samples显示文摘 | Pasquali C E Gallego-Pico A Fernandez Hernando P | 2010 | Microchemical Journal2010，94，1： | 1 |
| 16 | 17-hydroxyprogesterone responses to gonadotropinreleasing hormone disclose distinct phenotypes of functional ovarian hyperandrogenism and polycystic ovary syndrome显示文摘 | Pasquali R Patton L Pocognoli P | 2007 | J Clin Endocrinol Metab2007，92，11： | 1 |
| 17 | Insulin-sensitizing agents in polycystic ovary syndrome显示文摘 | Pasquali R Gambineri A | 2006 | Eur J Endocrinol2006，154，6： | 1 |
| 18 | Survival after resection for ductual adenocarcinoma of the pancreas显示文摘 | Sperti C Pasquali C Piccoli A | 1996 | Br J Surg1996，83，5： | 1 |
| 19 | Three dimensional(3D)analysis of the morphologicai changesinduced by 50Hz magneticfield exposure on humanlymphoblastoid cell(Raji)显示文摘 | Lisi A Pozzi D Pasquali E | 2000 | Bioelectromagnetics2000，21，： | 1 |
| 20 | Li/Li1+xV3O8 secondary batteries显示文摘 | Pistoia G Pasquali M Wang G | 1990 | J Electrochem Soc1990，137，8： | 1 |
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