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| 1 | MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth显示文摘一幅 microRNA 表示屏幕被执行从良性的 melanocytic nevi 在 laser-microdissected 纸巾分析 157 不同 microRNAs (n = 10 ) 并且主要恶意的黑瘤(n = 10 ) ,用量的即时 PCR。微分表示被作出对有利的裁决 72 microRNAs。microRNAs 的 let-7 家庭的成员是显著地, down 作为与良性的 nevi 相比在主要黑瘤调整了,为是的这些分子的一个可能的角色暗示肿瘤在恶意的黑瘤压制 ors。有趣地,类似的调查结果为肺和结肠癌被描述了。在黑瘤房间试管内 down 的 let-7b 的 Overexpression 调整了 cyclins 的表示 D1, D3,和 A,和 cyclin 依赖的 kinase (Cdk ) 4,所有哪个被描述了在黑瘤开发起一个作用。蛋白质表示上的 let-7b 的效果由于单个 mRNAs 的 3'-untranslated 区域(3'UTRs ) 指向,为 cyclin D1 由记者基因分析例示。与它细胞周期管理者上的 down modulating 效果一致, let-7b 禁止了细胞周期前进和黑瘤细胞的抛锚无关的生长。总起来说,这些调查结果不仅指向早黑瘤开发的新规章的机制,而且可以打开大街因为未来指向了这个肿瘤的治疗。 | Julia Schultz Peter Lorenz Gerd Gross Saleh Ibrahim Manfred Kunz | 2008 | Cell Research2008，18，5： | 45 |
| 2 | Gap filling strategies for long term energy flux data sets显示文摘 | Eva Falge Dennis Baldocchi Richard Olson Peter Anthoni Marc Aubinet Christian Bernhofer George Burba Reinhart Ceulemans Robert Clement Han Dolman André Granier Patrick Gross Thomas Grünwald David Hollinger Niels-Otto Jensen Gabriel Katul Petri Keronen And | 2001 | Agricultural and Forest Meteorology2001，，1： | 2 |
| 3 | Fine root growth and demographic responses to nutrient patches in four old-field plant species显示文摘 | GROSS K L PETER A PREGITZER K S | 1993 | Oecologla1993，95，： | 1 |
| 4 | The role of V2 vasopressin antagonists in hyponatremia 显示文摘 | Catrin Palm Doreen Reimann Peter Gross | 2001 | Cardiovasc Res2001，51，： | 1 |
| 5 | Mechanically milled Mg composites for hydrogen storage The transition to a steady state composition 显示文摘 | Peter Spatz Andreas Zuttel | 1996 | Journal of Alloys and Compounds1996，，240： | 1 |
| 6 | Advances in the therapy of Wegener's granulomatosis显示文摘 | Hellmich Bernhard Lamprecht Peter Gross Wolfgang | 2006 | Current Opinion in Rheumatology2006，18，1： | 1 |
| 7 | Fine root growth and demographic responses to nutrient patches in four old field plant species显示文摘 | Gross K L Peter A Pregitzer K S | 1993 | Oecologia1993，95，11： | 1 |
| 8 | Fine root growth and demographic responses to nutrient patches in four old-field plant species显示文摘 | Gross KL Peters A Pregitzer KS | | 0，，： | 1 |
| 9 | FDI,Regional Different and Economic Growth-Panel Data Evidence from China显示文摘 | Buckley Peter Clegg Jeremy Wang Chengqi Gross Adam | | 0，，22： | 1 |
| 10 | Randomized controlled trial of recombinant alpha-2a-interferon for chronic hepatitis C显示文摘 | David D. Douglas MD Dr. Jorge Rakela MD Hsiang Ju Lin DSc F. Blaine Hollinger MD Howard F. Taswell MD Albert J. Czaja MD John B. Gross MD Monte L. Anderson MD Kevin Parent MD C. Richard Fleming MD John R. Cangemi MD Peter C. O’Brien PhD Pauline E. Powis R | 1993 | Digestive Diseases and Sciences1993，，4： | 1 |
| 11 | Loading mobile phones in a multi-option society显示文摘 | Peter Gross Stefan Bertschi | 2006 | Knowledge Technology & Policy2006，，1： | 1 |
| 12 | Vaptans and the Treatment of Water-Retaining Disorders显示文摘 | Friedericke Quittnat Peter Gross | 2006 | Seminars in Nephrology2006，，3： | 1 |
| 13 | Clearing Away the Junk, Court-Appointed Experts, Scientifically Marginal Evidence, and the Silicone Gel Breast Implant Litigation显示文摘 | | 2001 | Food Drug2001，56，： | 1 |
| 14 | Partitioning of synchronous machine windings for internal fault analysis显示文摘 | Peter P Reichmeider Dale Querrey Charles A Gross | 2000 | IEEE Transactions Energy Conversion2000，15，4： | 1 |
| 15 | Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist: A randomized double-blind multicenter trial显示文摘 | Alexander L. Gerbes Veit Gülberg Pere Ginès Guy Decaux Peter Gross Hassan Gandjini Jacques Djian | 2003 | Gastroenterology2003，，4： | 1 |
| 16 | In vitro bioconversion of polyphenols from black tea and red wine/grape juice by human intestinal microbiota displays strong interindividual variability显示文摘 | Gross Gabriele Jacobs Doris M Peters Sonja | 2011 | Journal of agricultural and food chemistry2011，58，10： | 1 |
| 17 | Preliminary Pharmacokinetics and Pharmacodynamics of an Ultra-Short-Acting Opioid: Remifentanil (GI87084B)显示文摘 | Peter S. A. Glass David Hardman Yochiro Kamiyama Timothy J. Quill G. Marton K. H. Donn C. M. Grosse D. Hermann | 1993 | Anesthesia & Analgesia1993，，5： | 1 |
| 18 | Treatment of severe hyponatremia显示文摘 | Peter Gross | 2001 | Kidney International2001，60，： | 1 |
| 19 | Partitioning of synchronous machine windingsfor internal fault analysis显示文摘 | Peter P Reichmeider Dale Querrey Charles A Gross | 2000 | IEEE Transactions Energy Conversion2000，15，4： | 1 |
| 20 | Total process optimization in chemical engineering with evolutionary algorithms显示文摘 | Bernd Gross Peter Roosen | 1998 | Computers and Chemical Engineering1998，，： | 1 |
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