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| 1 | FAIR Principles:Interpretations and Implementation Considerations显示文摘The FAIR principles have been widely cited,endorsed and adopted by a broad range of stakeholders since their publication in 2016.By intention,the 15 FAIR guiding principles do not dictate specific technological implementations,but provide guidance for improving Findability,Accessibility,Interoperability and Reusability of digital resources.This has likely contributed to the broad adoption of the FAIR principles,because individual stakeholder communities can implement their own FAIR solutions.However,it has also resulted in inconsistent interpretations that carry the risk of leading to incompatible implementations.Thus,while the FAIR principles are formulated on a high level and may be interpreted and implemented in different ways,for true interoperability we need to support convergence in implementation choices that are widely accessible and(re)-usable.We introduce the concept of FAIR implementation considerations to assist accelerated global participation and convergence towards accessible,robust,widespread and consistent FAIR implementations.Any self-identified stakeholder community may either choose to reuse solutions from existing implementations,or when they spot a gap,accept the challenge to create the needed solution,which,ideally,can be used again by other communities in the future.Here,we provide interpretations and implementation considerations(choices and challenges)for each FAIR principle. | Annika Jacobsen Ricardo de Miranda Azevedo Nick Juty Dominique Batista Simon Coles Ronald Cornet Melanie Courtot Merce Crosas Michel Dumontier Chris T.Evelo Carole Goble Giancarlo Guizzardi Karsten Kryger Hansen Ali Hasnain Kristina Hettne Jaap Heringa Rob W.W.Hooft Melanie Imming Keith G.Jeffery Rajaram Kaliyaperumal Martijn GKersloot Christine R.Kirkpatrick Tobias Kuhn Ignasi Labastida Barbara Magagna PeterMcQuilton Natalie Meyers Annalisa Montesanti Mirjam van Reisen Philippe Rocca-Serra Robert Pergl Susanna-Assunta Sansone Luiz Olavo Bonino da Silva Santos Juliane Schneider George Strawn Mark Thompson Andra Waagmeester Tobias Weigel Mark D.Wilkinson Egon L.Willighagen Peter Wittenburg Marco Roos Barend Mons Erik Schultes | 2020 | Data Intelligence2020，2，1： | 26 |
| 2 | Mutants, Overexpressors, and Interactors of Arabidopsis Plastocyanin Isoforms: Revised Roles of Plastocyanin in Photosynthetic Electron Flow and Thylakoid Redox State显示文摘二相应 plastocyanin isoforms 被基因 PETE1 和 PETE2 编码为 Arabidopsis thaliana 的原子染色体。PETE2 抄本被表示在更加高水平和 PETE2 蛋白质是更丰富的 isoform。在 PETE 基因的空变化导致了植物,指明的 pete1 和 pete2,与减少的 plastocyanin 内容。尽管有在超过 90% 减少 plastocyanin 层次,而 pete1 大美人种,然而,它的自己上的一个 pete2 0 变化仅仅稍微影响光合作用和生长的率,与大约 6080% 野类型的 plastocyanin 水平,没显示出任何改变。因此, plastocyanin 集中不在最佳的生长条件下面为光合的电子流动正在限制,也许为蛋白质暗示另外的可能的生理的角色。确实, plastocyanin 以前被建议了在 thylakoid 氧化还原作用反应与细胞色素 c6A (Cyt c6A ) 合作,但是我们不为在二蛋白质之间的一个物理相互作用发现证据,用在酵母的相互作用试金。我们在酵母相互作用试金观察了 Cyt c6A 的 homodimerization,而且 Cyt c6A homodimers 没能与 plastocyanin 交往。而且, atc6-1 pete1 的 phenotypic 分析和 atc6-1 pete2 加倍异种,每缺乏的 Cyt c6A 并且二编码 plastocyanin 基因之一,没能揭示任何基因相互作用。在 pete1 pete2 的 PETE1 或 PETE2 的 Overexpression 在实质上野类型的光合的性能的两倍猛烈变异的背景结果,排除二 plastocyanin isoforms 能在 thylakoid 有不同函数的可能性电子流动。 | Paolo Pesaresi Michael Scharfenberg Martin Weigel Irene Granlund Wolfgang R Schroder Giovanni Finazzi Fabrice Rappaport Simona Masiero Antonella Furini Peter Jahns Dario Leister | 2009 | Molecular Plant2009，2，2： | 7 |
| 3 | The role and clinical value of EUS in a multimodality esophageal carcinoma staging program with CT and positron emission tomography显示文摘 | Patrick R. Pfau Scott B. Perlman Peter Stanko Terrence J. Frick Deepak V. Gopal Adnan Said Zhengjun Zhang Tracey Weigel | 2007 | Gastrointestinal Endoscopy2007，，： | 1 |
| 4 | Supermolecular structure and orientation of blown cellulosic films 显示文摘 | Hans-Peter Fink Peter Weigel Andreas Bohn | 1999 | Journal of Macromolecular Science1999，38，56： | 1 |
| 5 | The role and clinical value of EUS in a multimodality esophageal carcinoma staging program with CT and positron emission tomography显示文摘 | Patrick R. Pfau Scott B. Perlman Peter Stanko Terrence J. Frick Deepak V. Gopal Adnan Said Zhengjun Zhang Tracey Weigel | 2007 | Gastrointestinal Endoscopy2007，，3： | 1 |
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