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| 1 | Targeting head and neck tumoral stem cells: From biologicalaspects to therapeutic perspectives显示文摘Head and neck squamous cell cancer(HNSCC) is the sixth most common cancer in the world. Effective therapeutic modalities such as surgery, radiation, chemotherapy and combinations of each are used in the management of the disease. In most cases, treatment fails to obtain total cancer cure. In recent years, it appears that one of the key determinants of treatment failure may be the presence of cancer stem cells(CSCs) that escape currently available therapies. CSCs form a small portion of the total tumor burden but may play a disproportionately important role in determining outcomes. CSCs have stem features such as self-renewal, high migration capacity, drug resistance, high proliferation abilities. A large body of evidence points to the fact that CSCs are particularly resistant to radiotherapy and chemotherapy. In HNSCC, CSCs have been increasingly shown to have an integral role in tumor initiation, disease progression, metastasis and treatment resistance. In the light of such observations, the present review summarizes biological characteristics of CSCs in HNSCC, outlines targeted strategies for the successful eradication of CSCs in HNSCC including targeting the self-renewal controlling pathways, blocking epithelial mesenchymal transition, niche targeting, immunotherapy approaches and highlights the need to better understand CSCs biology for new treatments modalities. | Benoîte Méry Jean-Baptiste Guy Sophie Espenel Anne-Sophie Wozny Stéphanie Simonet Alexis Vallard Gersende Alphonse Dominique Ardail Claire Rodriguez-Lafrasse Nicolas Magné | 2016 | World Journal of Stem Cells2016，8，1： | 3 |
| 2 | Performance characteristics of a dual focus X-ray alignment microscope 显示文摘 | FELDMAN M LIU L PHANI S | 1995 | Journal of Vacuum Science & Technology: B1995，13，6： | 1 |
| 3 | Synthesis and characterization of zinc aluminum oxide thin films by sol–gel technique显示文摘 | A.R Phani M Passacantando S Santucci | 2001 | Materials Chemistry and Physics2001，，1： | 1 |
| 4 | Low Temperature Growth of Nanocrystalline Fe2TiO5 Perovskite Thin Films by Sol-gel Process Assisted by Microwave Irradiation 显示文摘 | Phani A R Ruggieri F Passacantando M | 2008 | Ceramics International2008，34，： | 1 |
| 5 | Structural characterization of bulk ZnWO4 prepared by solid state method显示文摘 | PHANI A R PASSACANTADO M LOZZI E L | 2000 | J Mater Sci2000，35，： | 1 |
| 6 | Postion dependent multi body dynamic modeling of machine tools based on improved reduced order models 显示文摘 | Law M Phani A S Altintas Y | 2013 | Journal of Manufacturing Science and Engineering2013，135，02： | 1 |
| 7 | Position- dependent multibody dynamic modeling of machine tools based on improved reduced ordermodels显示文摘 | Law M Srikantha Phani A Altintas Y | 2013 | ASME Journal of Manufacturing Science and Engineering2013，135，2： | 1 |
| 8 | Rapid Evaluation and Optimization of Machine Tools with Position-Dependent Stability显示文摘 | Law M Altintas Y Phani A S | 2013 | International Journal of Machine Tools and Manufacture2013，68，5： | 1 |
| 9 | Engineering triiodothyronine(T3)nanoparticle for use in ischemic brain stroke显示文摘 | Alexander M Vijaykumar S Phani KT | 2013 | Drug Deliv Translat Res2013，11，4： | 1 |
| 10 | Rapid evaluation and optimization of machine tools with position-dependent stability 显示文摘 | Law M Ahintas Y Phani A S | 2013 | International Journal of Machine Tools & Manufacture2013，68，： | 1 |
| 11 | Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection显示文摘 | Etienne Patin Zoltán Kutalik Julien Guergnon Stéphanie Bibert Bertrand Nalpas Emmanuelle Jouanguy Mona Munteanu Laurence Bousquet Laurent Argiro Philippe Halfon Anne Boland Beat Müllhaupt David Semela Jean–Fran?ois Dufour Markus H. Heim Darius Moradpour A | 2012 | Gastroenterology2012，，5： | 1 |
| 12 | Role of serotonin in memory impairment显示文摘 | Marie-Christine B Stéphanie M Louis S | 2000 | Finnish Med Socy Duodecim2000，32，3： | 1 |
| 13 | Modal coupling in micromechanical vibratory rate gyroscopes显示文摘 | PHANI A S SESHIA A A PALANIAPAN M | 2006 | IEEE Sensors2006，6，5： | 1 |
| 14 | Comparative study of some surface active properties of fructose esters and commercial sucrose esters显示文摘 | SAMIA S STPHANIE O JEAN M E | 2003 | Colloids and Surfaces A:Physicochemical and Engineering Aspects2003，227，1： | 1 |
| 15 | Deep desulfurization:reactions,catalysts and technological challenges显示文摘 | MICHLE B GRALD D M STPHANIE P | 2003 | Catalysis Today2003，84，34： | 1 |
| 16 | Occurrence of the three major Vibrio species pathogenic for human in seafood products consumed in France using real-time PCR显示文摘 | Annick Robert-Pillot Stéphanie Copin Charlotte Himber Mélanie Gay Marie-Laure Quilici | 2014 | International Journal of Food Microbiology2014，，： | 1 |
| 17 | An efficient synthesis of 5-substituted 1H-tetrazoles using Zn/A1 hydrotalcite catalyst显示文摘 | Lakshmi Kantam M Shiva Kumar K B Phani Raja K | 2006 | Journal of Molecular Catalysis A: Chemical2006，，： | 1 |
| 18 | Data quality in water analysis:validation of ion chromatographic method for the determinationof routine ions in potable water显示文摘 | Phani M Efthimios L Leonidas K S | 2007 | Desalination2007，213，： | 1 |
| 19 | 显示文摘 | JAYALAKSHMI M VENUGOPAL N PHANI R K | 2006 | J Power Sources2006，158，2： | 1 |
| 20 | Sliek water and hybrid fracs in the bossier:some lessons learnt显示文摘 | Mukul M Sharma Phani B Gadde | 2004 | SPE 898762004，，： | 1 |
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