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| 1 | Detection of soluble TRAIL in HBV infected patients and its clinical implications显示文摘AIM: To detect the expression of soluble TRAIL (TNF-related apoptosis inducing ligand, TRAIL) in the peripheral blood of HBV infected patients and try to elucidate whether the expression level of sTRAIL have any correlativity with the clinical staging, the expression level of HBV markers and the degree of liver damage.METHODS: 52 cases of HBV infected patients were investigated, induding 8 HBV carriers, 30 chronic hepatitis B, 11 drrhotics and 3 HBV infection related hepatocellular carcinoma. Expression of soluble TRAIL and markers of the hepatitis B were mearsured by enzyme-linked immunosorbent assay.RESULTS: The expression level of sTRAIL in the peripheral blood of the HBV infected patients was significantly higher than that of healthy controls (1378.35±540.23 pg/ml vs 613.75±175.80 pg/ml, P<0.001). In the group of chronic hepatitis, the expression level of sTRAIL was coincident with the status of the disease and was significantly correlated with the level of ALT. In the group of cirrhosis and liver cancer, its expression level was significantly higher than that of the healthy persons and HBV carriers, but lower than that of the hepatitis B patients; meanwhile, the expression of siRAIL did not have any correlativity with the functional indexes of the liver. CONCLUSION: The soluble TRAIL in the HBV infected people may participate in the liver damage. Our results indicated that the expression level of soluble TRAIL may reflect the ravage of liver caused by host immune reaction to a certain degree. | Li-Hui Han Wen-Sheng Sun Chun-Hong Ma Li-Ning Zhang Su-Xia Liu Qiu Zhang Li-Fen Gao,Institute of Immunology,Medical College of Shandong University,Jinan 250012,Shandong Province,China You-Hai Chen,Institute for Human Gene Therapy,University of Pennsylvania,Philadelphia PA 19104,USA | 2002 | World Journal of Gastroenterology2002,8,6: | 12 |
| 2 | SYNTHESIS OF OLIGO(OXYETHYLENE) MACROMONOMER CARRYING SULFONATE显示文摘This letter reports the synthesis of macromonomers, in which oligo(oxyethylene) chain and sodium salfonate are contained together. This kind of macromonomers has potential application in the fabrication of functional polymers, especially in the study of single-ionic conductors. Some preliminary characterizations of the monomer by IR, IH-NMR, etc. are given as well. | Sheng Shui ZHANG~*, Qing Guo LIU Laboratory of Solid State lonics, University of Science and Technology Beijing, Beijing 100083 Lei Ling YANG Beijing Research Institute of Chemical Industry, Beijing 100013 Gregory C FARRINGTON Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA 19104, USA | 1992 | Chinese Chemical Letters1992,3,10: | 4 |
| 3 | Twinning in Intermetallic Compounds Are Long Shear Vectors and/or Shuffles Really Necessary?显示文摘In this paper the geometric description and general theory of mechanical twinning are reviewed, the twins in general lattices and superlattices are summarized, and the kinetic process by which mechanical twins form is revisited. A case study of mechanical twinning of HfV2+Nb, (cubic) Laves phase, is presented and the synchroshear of selected atomic layers is proposed to explain the physical process of twin formation. If the twins form in this way, then long shear vectors and / or atomicshuffles are not really necessary. | F.M.Chu David P.Pope Dept.of Materials Science and Engineering,University of Pennsylvania,Philadelphia,PA 19104,USA | 1993 | Journal of Materials Science & Technology1993,9,5: | 4 |
| 4 | Multi-Volume CAD Modeling for Heterogeneous ObjectDesign and Fabrication显示文摘1IntroductionWiththeadvancementofdesignandmanufacturingtechnology,theutilizationofintegratedComputer--AidedDesign/Computer-AidedEngineering/Computer-AidedManufacturing,i.e.,CAD/CAE/CAMandrapidprototyping,andtheincorporationofconcurrentengineeringillt... | SUN Wei(Department of Mechanical Engineering and MechanicsDrexel University, Philadelphia, PA 19104, U.S.A.)E-mail: sunwei@drexel.edu or rpdc@drexel.edu | 2000 | Journal of Computer Science & Technology2000,15,1: | 3 |
| 5 | Benign chon- droblastoma, in:Dahlin's BoneTumors 显示文摘 | Philadelphia PA Lippincott Raven Unni KK | 1996 | General aspects and data on 11 087 eases1996,,: | 1 |
| 6 | Snail Hosts of Paragonimus in Asia and the Americas显示文摘We have undertaken a comprehensive review of snail hosts of Paragonimus world-wide exclusive of Africa based on modern malacological data, where available, and with consideration of the phylogeny of the snail groups involved. This is the first comprehensive review since those made by Chen (1979) and Chen et al (1983), and there have been considerable taxonomic changes over the past decade. A number of names and concepts found in the medical malacological and parasitological literature up to the present time require revision or correction. There are vast radiations of snails of the superfamilies Cerithiacea and Rissoacea involved in the transmission of Paragonimus in China. We list 54 species world-wide of which 35(65%) occur in China. Revisions and corrections pertaining to China include: (i) The family Hydrobiidae does not occur in China or S.E. Asia,and the Pomatiopsidae should be used. (ii) The genus Bythinella is entirely European (Hydrobiidae: Amnicolinae). The so-called Bythinella of China belongs to the genus Erhaia (Pomatiopsidae). (iii) The generic name Pseudobythinella described from China is preoccupied, a junior synonym of Pseudobythinella Melville 1956, a fossil from England. All Chinese Pseudobythinella are now classified as Erhaia. (iv) Akiyoshia has been used as a generic name for some snails in Hunan transmitting Paragonimus. Akiyoshia is from Japan and biological/ecological data indicate that the Chinese taxon is not Akiyoshia. (v)The genus Tricula in recent Chinese literature is comprised of four genera determined by detailed comparative anatomical data: Tricula, Neotricula, Gammatricula, and Jinhongia.Shells cannot be used to discriminate among them. (vi) Tricula cristella has been consistently misidentified in collections in China and literature. However, genuine T cristella does transmit Paragonimus skrjabini. (vii) Tricula minutoides in the Chinese literature has been misidentified, and specimens are T. crisIella. (viii) The genus Melamia and the family Melaniidae are used in the Chinese literature. The so-called melaniid snails belong to the families Thiaridae, Pleuroceridae, and Melanopsidae. Asian Semisulcospira is pleurocerid while Melanoides and Tarebia are thiarid. (ix) Semisulcospira libertina is correctly identified for populations ranging throughout Japan to Taiwan. This species is most probably not distributed throughout all south China, and intense systematic research on Semisulcospira is needed. A modern classification is given for snails transmitting | G. M. DAVIS CHEN CUI-E KANG ZAI-BIN AND LIU YUE-YING(Academy of Natural Sciences of Philadelphia, 1900 Benjamin Franklin Parkway, Philadelphia, PA 19103, USA Institute of Parasitology,Zhejiang Academy of Medical Sciences, Hangzhou, Zhejiang Province,China | 1994 | Biomedical and Environmental Sciences1994,7,4: | 1 |
| 7 | Effect of Tempered Martensite on Magnetomechanical Damping of Ferritic Matrix Dual Phase Alloys显示文摘The influence of the volume fraction of tempered martensite on magnetomechanical damping of theferritic matrix in dual-phase alloys was studied.The experimental results showed that(1)dual-phase damping alloy is of good combination of strength and toughness: (2)good damping ca-pacity(Q-1≥5.0×10-3)can be obtained in dual-phase alloys only when the volume fraction oftempered martensite was controlled properly.The effect of martensite on magnetomechanical damp-ing of the ferritic matrix was analysed.The damping capacity of dual-phase alloys was related to thevolume fraction Vm of tempered martensite by Q<sup>-1=Q<sup>-1 (1-Vm/1+BVm)at small vibration strainamplitudes εA≤5.0×10-6. | Junsheng LU Xiaodong LIU Wenjie ZHENG Baorong WU Hui BI Central Iron and Steel Research Institute,Beijing,100081,ChinaGuijin WANG Dept.of Materials Science and Engineering,University of Pennsylvania,Philadelphia,PA 19104,USA | 1993 | Journal of Materials Science & Technology1993,9,4: | 0 |
| 8 | SYNTHESIS AND CHARACTERIZATION OF STRUCTURALLY WELL-DEFINED POLYMER-INORGANIC HYBRID NANOPARTICLES VIA ATRP显示文摘Atom transfer radical polymerization (ATRP) using cuprous chloride/2,2'-bipyridine (bipy) was applied to graft polymerization of styrene on the surface of silica nanoparticles to synthesize polymer-inorganic hybrid nanoparticles. 2-(4-Chloromethylphenyl) ethyltriethoxysilane (CTES) was immobilized on the surface of silica nanoparticles through condensation reaction of the silanol groups on silica with triethoxysilane group of CTES. Then ATRP of St was initiated by this surface-modified silica nanoparticles bearing benzyl chloride groups, and formed PSt graft chains on the surface of silica nanoparticles. The thickness of the graft chains increased with reaction time. End group analysis confirmed the occurrence of ATRP. Thermal analysis indicated that thermal stabilization of these resulting hybrid nanoparticles also increases with polymerization conversion. The results above show that this 'grafting from' reaction could be used for the preparation of polymer-inorganic hybrid nanoparticles with controlled structure of the polymer's end groups. | Jie Bai Jie-bin Pang Kun-yuan Qiu Yen Wei Department of Polymer Science & Engineering College of Chemistry & Molecular Engineering Peking University Beijing 100871, China Department of Chemistry Drexel University Philadelphia, PA 19104 USA | 2002 | Chinese Journal of Polymer Science2002,20,3: | 0 |
| 9 | SYNTHESIS OF HYBRID MESOPOROUS POLYSTYRENE-SILICA MATERIALS WITH NON-SURFACTANT CITRIC ACID AS TEMPLATE VIA SOL-GEL PROCESS显示文摘Hybrid mesoporous polystyrene-silica materials were successfully prepared through HCl-catalyzed sol-gelreactions of tetraethyl orthosilicate (TEOS) and triethoxysilyl-functionalized polystyrene obtained via atom transfer radicalpolymerization (ATRP) of styrene, in the presence of citric acid (CA) as non-surfactant template or pore-forming agent andfollowed by ethanol extraction to remove template molecules. The materials were characterized by infrared spectroscopy(IR), N2 adsorption-desorption measurements, powder X-ray diffraction (XRD), thermogravimetric analysis (TGA) andtransmission electron microscopy (TEM). The results indicate that the materials prepared with 50 wt%-60 wt% templatecontents have average pore size s of 2-3 nm and large surface areas (ca. 886 m2/g) as well as high pore volumes (ca.0.53 cm3/g). The mesoporosity arises from interconnected channels and pores with disordered arrangements. The porediameters and pore volumes increase as the template content is increased. The pore diameters show a little change uponheating at 200℃ overnight. However, the materials do not have good hydrothermal stability. | Jie Bai Jin-yu Zheng Kun-yuan Qiu Yen Wei Department of Polymer Science & Engineering College of Chemistry & Molecular Engineering, Peking University Beijing 100871, China Department of Chemistry, Drexel University, Philadelphia, PA 19104, USA | 2002 | Chinese Journal of Polymer Science2002,20,6: | 0 |
| 10 | Theory of Electron Emission in High Fields from Atomically Sharp Emitters:1.Applicability of the Fowler-Nordheim Model显示文摘Field emission from metallic emitter tips is generally described by the Fowl-er-Nordheim theory, which is based on a planar model of the tip with a classical imagecorrection. Within the free electron model and the WKB approximation, the planar tipmodel leads to the well-known Fowler-Nordheim cquation. The form of this equationpredicts that a plot of log J/ F^2 versus 1/F; where J is the current density and F, | Jun He,P. H. Cutler, N. M. Miskovsky, T. E. Feuchtwang Department of Physics, The Pennsylvania State University 104 Davey Laboratory, UniversityPark, PA 16802andT. E. Sullivan Departrnent of Electrical Engineering, Temple University, Philadelphia, PA 19122 | 1992 | 云南大学学报(自然科学版)1992,14,S1: | 0 |
| 11 | High-Sensitivity Magnetization Measurements显示文摘The three most common instruments for high-sensitivity magnetization measurements (the vibrating-sample magnetometer, the alternating gradient magnetometer, and the SQUID magnetometer) are described and their limiting sensitivities are discussed. The advantages and disadvantages of each are described. Magnetometers using micro-machined force detectors are briefly mentioned. | C.D. Graham (Dept. of Materials Science, University of Pennsylvania, Philadelphia, PA 19104, USA) | 2000 | Journal of Materials Science & Technology2000,16,2: | 0 |
| 12 | Relationship between Magnetomechanical Damping Capacity and Vibration Modes显示文摘The mathematical expressions for magnetomechanical damping capacity are presented by applyingSmith-Birchak’s model in torsion pendulum and cantilever beam.The peak value ψ_p is found to berelated to physical parameters and material constants in the form Kλ_s=αψ_pε_p.which can be used toestimate the magnetostrictive constant λ_s from the damping capacity-strain amplitude curve.A goodagreement of experimental data and theoretical prediction was observed in HIDAMETSCr15A13NiCu. | Junsheng LU Baorong WU Dept.of Alloy Steel,Central Iron and Steel Research Institute Beijing,100081,ChinaG.J.Wang Dept.of Materials Science and Engineering,University of Pennsylvania,Philadelphia,PA 19104,USA | 1993 | Journal of Materials Science & Technology1993,9,5: | 0 |
| 13 | Evaluation and Comparison Research on the Support of Websites to Enterprise's E-Commerce显示文摘This paper comparatively analyzes the existing evaluation index of websites, and puts forward the evaluation index and method about the support of a website to enterprise’s e-commerce. Through researching on 56 super enterprises of information industry in Sichuan province, throughout China and the world, analyzing and comparatively studying the support ability of a website to an enterprise’s e-commerce, this paper brings forward using five levels to categorize the support ability of a website to enterprise’s e-commerce. In the end, the flaw of enterprise’s e-commerce practice in Sichuan province and corresponding countermeasure will be illustrated. | SHAO Peiji, HUANG Yixiao, WAN Jie, YANG Jing ( School of Management, University of Electronic Science and Techonology of China Chengdu 610054 China Johnson & Johnson, Philadelphia PA 19104 USA) | 2004 | Journal of Electronic Science and Technology of China2004,2,3: | 0 |