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| 1 | Laser produced electromagnetic pulses: generation, detection and mitigation显示文摘This paper provides an up-to-date review of the problems related to the generation,detection and mitigation of strong electromagnetic pulses created in the interaction of high-power,high-energy laser pulses with different types of solid targets.It includes new experimental data obtained independently at several international laboratories.The mechanisms of electromagnetic field generation are analyzed and considered as a function of the intensity and the spectral range of emissions they produce.The major emphasis is put on the GHz frequency domain,which is the most damaging for electronics and may have important applications.The physics of electromagnetic emissions in other spectral domains,in particular THz and MHz,is also discussed.The theoretical models and numerical simulations are compared with the results of experimental measurements,with special attention to the methodology of measurements and complementary diagnostics.Understanding the underlying physical processes is the basis for developing techniques to mitigate the electromagnetic threat and to harness electromagnetic emissions,which may have promising applications. | Fabrizio Consoli Vladimir TTikhonchuk Matthieu Bardon Philip Bradford David CCarroll Jakub Cikhardt Mattia Cipriani Robert JClarke Thomas ECowan Colin NDanson Riccardo De Angelis Massimo De Marco Jean-Luc Dubois Bertr Etchessahar Alejro Laso Garcia David IHillier Ales Honsa Weiman Jiang Viliam Kmetik Josef Krása Yutong Li FredériéLubrano Paul McKenna Josefine Metzkes-Ng Alexre Poyé Irene Prencipe Piotr Ra¸czka Rol ASmith Roman Vrana Nigel CWoolsey Egle Zemaityte Yihang Zhang Zhe Zhang Bernhard Zielbauer David Neely | 2020 | High Power Laser Science and Engineering2020，8，2： | 3 |
| 2 | Appropriateness of systemic treatments in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors显示文摘AIM:To evaluate systemic treatment choices in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors(PNETs)and provide consensus treatment recommendations.METHODS:Systemic treatment options for pancreatic neuroendocrine tumors have expanded in recent years to include somatostatin analogs,angiogenesis inhibitors,inhibitors of mammalian target of rapamycinand cytotoxic agents.At this time,there is little data to guide treatment selection and sequence.We therefore assembled a panel of expert physicians to evaluate systemic treatment choices and provide consensus treatment recommendations.Treatment appropriateness ratings were collected using the RAND/UCLA modified Delphi process.After studying the literature,a multidisciplinary panel of 10 physicians assessed the appropriateness of various medical treatment scenarios on a 1-9 scale.Ratings were done both before and after an extended discussion of the evidence.Quantitative measurements of agreement were made and consensus statements developed from the second round ratings.RESULTS:Specialties represented were medical and surgical oncology,interventional radiology,and gastroenterology.Panelists had practiced for a mean of15.5 years(range:6-33).Among 202 rated scenarios,disagreement decreased from 13.2%(26 scenarios)before the face-to-face discussion of evidence to 1%(2)after.In the final ratings,46.5%(94 scenarios)were rated inappropriate,21.8%(44)were uncertain,and30.7%(62)were appropriate.Consensus statements from the scenarios included:(1)it is appropriate to use somatostatin analogs as first line therapy in patients with hormonally functional tumors and may be appropriate in patients who are asymptomatic;(2)it is appropriate to use everolimus,sunitinib,or cytotoxic chemotherapy therapy as first line therapy in patients with symptomatic or progressive tumors;and(3)beyond first line,these same agents can be used.In patients with uncontrolled secretory symptoms,octreotide LAR doses can be titrated up to 60 mg every4 wk or up to 40 mg every 3 or 4 wk.CONCLUSION:Using the Delphi process allowed physician experts to systematically obtain a consensus on the appropriateness of a variety of medical therapies in patients with PNETs. | Jonathan R Strosberg George A Fisher Al B Benson Lowell B Anthony Bulent Arslan John F Gibbs Edward Greeno Renuka V Iyer Michelle K Kim William J Maples Philip A Philip Edward M Wolin Dasha Cherepanov Michael S Broder | 2015 | World Journal of Gastroenterology2015，21，8： | 2 |
| 3 | Interference free and simpyfied liquid chromatography-based determination of thiopurine S-methyltransferase activity in erythrocytes 显示文摘 | Maurice NK Norbert E Philipe NK ct al | 2005 | J Chromatogr B2005，821，： | 1 |
| 4 | Models for gas/particle partitioning, transformation and air/water surface exchang of PCBs and PCDD/Fs in CMAQ显示文摘 | MENG FAN ZHANG BAO-NING PHILIP GBOR et al | 2007 | Atmospheric Environment2007，41，39： | 1 |
| 5 | Using Dempster–Shafer to incorporate knowledge into satellite image classification显示文摘 | Bilal Al Momani Sally McClean Philip Morrow | 2006 | Artificial Intelligence Review (-)2006，，1： | 1 |
| 6 | Direct effeels of alcohol on hepatic fihrinolytie balance:lmpliealions for alcoholie liver disease显示文摘 | Devanshi Seth Philip J ttogg Mark D Gorrell el al | 2008 | Hepatology2008，48，： | 1 |
| 7 | Phase Ⅲ trail comparing chemotherapy plus once - daily twice - daily radiotherapy in stage Ⅲ non - small - cell lung cancer 显示文摘 | Furuse E Schild M Philip J ct al | 2002 | Int J Radial Oncol Biol Phys2002，54，2： | 1 |
| 8 | Stereotactic body radiation therapy (SBRT) for lung metastases 显示文摘 | Okunieff P Petersen AL Philip A | 2006 | Acta Oncol2006，45，7： | 1 |
| 9 | High - temperature electronics--a role for wide bandgap semiconductors 显示文摘 | Philip G Neudeck Roberts Okojie Liang- Yu Chen et al | 2002 | Proceedings of the IEEE2002，90，6： | 1 |
| 10 | A modification of Wenker's method of preparing ethyleneimine显示文摘 | Philip AL William AP Melvin LR | 1947 | J Am Chem Soc1947，69，6： | 1 |
| 11 | The macrophage is the predomi nant Inflammatory cell in renal allograft intimalarteritis 显示文摘 | Philip J Ian D Brent W er al | 2005 | Transplantion2005，79，： | 1 |
| 12 | Phase Ul study compar- ing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Ontology Group-directed intergroup trial S0205 显示文摘 | Philip P A Benedetti J Corless C L el al | 2010 | Journal of Clinical On- cology2010，28，22： | 1 |
| 13 | The promise and challenges of microalgai-derived biofuels 显示文摘 | Philip T Piekos Al Darzins | 2009 | Biofuels Bioproducts and Biorefining2009，3，4： | 1 |
| 14 | Homogcncouscatalytic hydrog e-nation of supercritical carbon dioxide显示文摘 | Philip G Jcssop Takao Ikariya ct al | 1994 | Nature1994，368，6468： | 1 |
| 15 | Analysis of sample-to cutoff ratios on ehemiluminescent imrnunoassays used for blood donor screening highlights the need for serologic confirmatory tes ting显示文摘 | Philip Kiely KW Susan Parker ct al | 2010 | TRANSFUSION2010，50，： | 1 |
| 16 | Phthalate ester leachates in aquatic mesocosms:Impliea- tions for ecotoxieity studies of endocrine disrupting com- pounds 显示文摘 | Scott M Weir Kimberly J Wooten Philip N Smith et al | 2014 | Chemosphere2014，103，： | 1 |
| 17 | Phase Ⅲ study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma:Southwest Ontology Group-directed intergroup trial S0205显示文摘 | Philip P A Benedetti J Corless C L el al | 2010 | J Clin Oncol2010，28，22： | 1 |
| 18 | Integrin linked kinase regulates osteopontin- dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells 显示文摘 | Mi ZY Guo HT Philip Y at al | 2006 | Carcinogenesis2006，27，6： | 1 |
| 19 | High-dose tamoxifen as an enhancer of etopside cytotoxicity,clinical effects and in vitro assessment in P-gly-coprotein显示文摘 | Philip P Horris AL | 1992 | Br J Cancer1992，66，： | 1 |
| 20 | Characterization of hepatitis B virus genotypes and quantitative hepatitis B surface antigen titres in North American tertiary referral liver centres显示文摘 | Stephen E. Congly Philip Wong Said A. Al‐Busafi Karen Doucette Scott K. Fung Peter Ghali Kevin Fonseca Robert P. Myers Carla Osiowy Carla S. Coffin | 2013 | Liver Int2013，，9： | 1 |
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