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10篇 您的检索式：作者名="Philips BS"

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		题名	作者	年代	出处	被引量
	1	Correlation and prognostic significance of beta-galactoside alpha-2,6-sialyltransferase and serum monosialylated alpha-fetoprotein in hepatocellular carcinoma显示文摘AIM: To investigate the correlation between tissue ST6Gal I and serum msAFP in HCC patients, and to investigate their prognostic significance.METHODS: Preoperative sera,paired tumorous and non-tumorous tissues were collected from 19 consecutive patients who had undergone surgical resection of HCC.ST6Gal T activities in the tissues were measured by an in vitro microsomal enzyme activity assay. The percentages of tumor-specific msAFP in the sera were also estimated by an isoelectric focusing-immunoblotting assay.RESULTS: The tumor ST6Gal I activity was negatively correlated with serum msAFP percentage (r = -0.53,P = 0.019). Both decreased tumor ST6Gal I activity andincreased serum msAFP percentage were associatedwith poor tumor cell differentiation. Univariate analyses showed that both decreased tumor ST6Gal T activity (P = 0.028), increased serum msAFP percentage (P = 0.034) and poor tumor cell differentiation (P = 0.031)were associated with shorter overall survival. Multivariate analysis using the Cox regression model showed that the preoperative serum msAFP percentage (P = 0.022)and tumor cell differentiation status (P = 0.048) were independent prognostic indicators for patient overall survival.CONCLUSION: Our results indicate that the presence of msAFP in blood circulation is associated with a decreased activity of ST6Gal I activity in HCC. Both tissue ST6Gal I and serum msAFP are potential prognostic markers for patients with operable HCC.	Terence CW Poon Clarissa HS Chiu Paul BS Lai Tony SK Mok Benny Zee Anthony TC Chan Joseph JY Sung Philip J Johnson	2005	World Journal of Gastroenterology2005，11，42：	4
	2	Anatomy of the Percutaneous Presacral Spacefor a Novel Fusion Technique显示文摘	Philip S Thomas F Day BS	2006	J Spinal Disord Tech2006，19，4：	1
	3	Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat显示文摘	Philip S Tsao BS Nobuo Aoki	1990	Circulation1990，82，4：	1
	4	Anatomical landmarks for safe elevation of the deep inferior epigastric perforator flap:A cadaveric study显示文摘	Saeed Chowdhry MD Ron Hazani MD Philip Collis BS	2010	Eplasty2010，2810，：	1
	5	Effects hemoglobin variants and chemically modified derivatives on anssys for glyeohemoglobin显示文摘	Lynn B Philip CC David BS	2001	Clin Chem2001，47，：	1
	6	Performance of theOraQuick and Hema-Strip rapid HIV antibody detection assaysby non-laboratorian显示文摘	Granade TC Perekh BS Philips SK	2004	J Clin Virol2004，30，3：	1
	7	Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat 显示文摘	Philip S Tsao BS Nobuo Aoki	1991	Circulation1991，82，4：	1
	8	Effects hemoglobin variants and chemically modified derivatives on anssys for glycohemoglobin显示文摘	Lynn B Philip CC David BS	2001	Clin Chem2001，47，：	1
	9	An analysis of the validity, of health questionnaires显示文摘	Suchman EA Philips BS Streib GF	1958	Soc l%rces1958，36，：	1
	10	Melatonin prevents amyloid protofibrillar induced oxidative imbalance and biogenic amine catabolism显示文摘	GUNASINGH M J PHILIP JE ASHOK BS	2008	Life Sci2008，83，34：	1

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