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| 1 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation: incidence and management显示文摘 | Picada R Winter RB Lonstein JE | 2000 | J Spinal Disord2000，13，1： | 1 |
| 2 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation:incidence and management显示文摘 | Picada R Winter RB Lonstein JE | 2000 | J Spinal Disord2000，13，1： | 1 |
| 3 | Postepemtive deep wound infection in adults after posterior lambosacral spine fusion with instrumentation:incidence and management显示文摘 | Picada R Winter RB Lonstein JE | 2000 | J spinal Disord2000，13，1： | 1 |
| 4 | Postoperative deep wound infection in adults after posterior lumbosacral spine fu- sion with instrumentation: incidence and management显示文摘 | Picada R Winter RB Lonstein JE | 2000 | Journal of Spinal Disorders & Techniques2000，13，1： | 1 |
| 5 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation : incidence and management 显示文摘 | Picada R Winter RB honstein JE | 2000 | Spinal Disord2000，13，： | 1 |
| 6 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation incidence and management显示文摘 | Picada R Winter RB Honstein JE e t al | 2000 | Spinal Disord2000，13，： | 1 |
| 7 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation:incidence and management显示文摘 | Picada R Winter R B Lonstein J E | 2000 | Journal of Spinal Disorders&Techniques2000，13，1： | 1 |
| 8 | Melatonin prevents oxidative stress,inflammatory activity,and DNA damage in cirrhotic rats显示文摘BACKGROUND Cirrhosis is an important health problem characterized by a significant change in liver parenchyma.In animals,this can be reproduced by an experimental model of bile duct ligation(BDL).Melatonin(MLT)is a physiological hormone synthesized from serotonin that has been studied for its beneficial properties,including its antioxidant potential.AIM To evaluate MLT’s effects on oxidative stress,the inflammatory process,and DNA damage in an experimental model of secondary biliary cirrhosis.METHODS Male Wistar rats were divided into 4 groups:Control(CO),CO+MLT,BDL,and BDL+MLT.MLT was administered(20 mg/kg)daily beginning on day 15 after biliary obstruction.On day 29 the animals were killed.Blood samples,liver tissue,and bone marrow were collected for further analysis.RESULTS BDL caused changes in biochemical and histological parameters and markers of inflammatory process.Thiobarbituric acid(0.46±0.01)reactive substance levels,superoxide dismutase activity(2.30±0.07)and nitric oxide levels(2.48±0.36)were significantly lower(P<0.001)n the groups that received MLT.DNA damage was also lower(P<0.001)in MLT-treated groups(171.6±32.9)than the BDL-only group(295.5±34.8).Tissue damage and the expression of nuclear factor kappa B,interleukin-1β,Nrf2,NQO1 and Hsp70 were significantly lower in animals treated with MLT(P<0.001).CONCLUSION When administered to rats with BDL-induced secondary biliary cirrhosis,MLT effectively restored the evaluated parameters. | Josieli R Colares Renata M Hartmann Elizângela G Schemitt Sandielly R B Fonseca Marilda S Brasil Jaqueline N Picada Alexandre S Dias Aline F Bueno Cláudio A Marroni Norma P Marroni | 2022 | World Journal of Gastroenterology2022，28，3： | 1 |
| 9 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation:incidence and management显示文摘 | Picada R Winter RB Lonstein JE | 2000 | J Spinal Disord2000，13，1： | 1 |
| 10 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation:incidence and management显示文摘 | Picada R Winter R B Lonstein JE | 2000 | J Spinal Disord2000，13，： | 1 |
| 11 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation: incidence and management显示文摘 | Picada R Robert B John E | 2000 | J Spin Disor2000，13，1： | 1 |
| 12 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation:incidence and management显示文摘 | Picada R Winter RB Lonstein JE | 2000 | J Spinal Disord2000，13，1： | 1 |
| 13 | Genotoxicity of diphenyl diselenide in bacteria and yeast显示文摘 | ROSA R M SULZBACHER K PICADA J N | 2004 | Mut Res2004，563，： | 1 |
| 14 | Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with inst- rumentation :incidence and management显示文摘 | Picada R Winter RB Lonstein JE | 2009 | J Spinal Disord2009，13，1： | 1 |
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