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| 1 | High prevalence of viable Mycobacterium avium subspecies paratuberculosis in Crohn's disease显示文摘AIM:To examine the detection rate of viable Mycobacterium avium subspecies paratuberculosis(MAP) in patients with inflammatory bowel disease [Crohn's disease(CD) and ulcerative colitis(UC)].METHODS:Thirty patients with CD(15 with at least one NOD2/CARD15 mutation),29 with UC,and 10 with no inflammatory bowel disease(IBD).were tested for MAP by polymerase chain reaction(specific IS900 fragment) and blood culture.RESULTS:MAP DNA was detected in all original blood samples and 8-wk blood cultures(CD,UC and non-IBD).Positive MAP DNA status was confirmed by dot blot assays.All 69 cultures were negative by acid-fast Ziehl-Neelsen staining.Viable MAP,in spheroplast form,was isolated from the 18-mo blood cultures of all 30 CD patients,one UC patient,and none of the non-IBD controls.No association was found between positive MAP cultures and use of immunosuppressive drugs or CDassociated single nucleotide polymorphisms.CONCLUSION:MAP is widely present in our area and MAP DNA can be recovered from the blood of CD,UC and non-IBD patients.However,MAP spheroplasts were only found in CD patients. | Juan L Mendoza Amparo San-Pedro Esther Culebras Raquel Cíes Carlos Taxonera Raquel Lana Elena Urcelay Fernando de la Torre Juan J Picazo Manuel Díaz-Rubio | 2010 | World Journal of Gastroenterology2010，16，36： | 5 |
| 2 | Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry显示文摘 | Lahoz A Donato M T Picazo L | 2007 | Toxicol In Vitro2007，21，7： | 1 |
| 3 | Influence of cadmium and nickel on growth, net photosynthesis and carbohydrate distribution in rice plants 显示文摘 | Moya J L Ros R Picazo I | 1993 | Photos Res1993，36，： | 1 |
| 4 | Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry 显示文摘 | LAHOZ A DONATO M T PICAZO L | 2007 | Toxicol In Vitro2007，21，7： | 1 |
| 5 | Influence of cadmium and nickel on growth, net photosynthesis and carbohydrate distribution in rice plants 显示文摘 | MOYA J L ROS R PICAZO I | 1993 | Photosynthesis Research1993，36，： | 1 |
| 6 | Influence of cadmium and nickel on growth,net photosynthesis and carbohydrate distribution in rice plants显示文摘 | MOYA J L ROS R PICAZO I | 1993 | Photosynthesis Research1993，36，： | 1 |
| 7 | Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tarldem mass spectrometry 显示文摘 | LAHOZ A DONATO M T PICAZO L | 2007 | Toxicol in Vitro2007，21，7： | 1 |
| 8 | Renal failure and acquired hypothyroidism显示文摘 | Del G Tapia L Picazo B | 2003 | Pediatr Nephrol2003，18，3： | 1 |
| 9 | Renal failure and acquired hypothyroidism显示文摘 | del-Rio Camacho G Tapia Ceballos L Picazo Angelin B | 2003 | Pediatr Nephrol2003，18，3： | 1 |
| 10 | Effects of LH administration at the end of an FSH superovulatory regimen on ovulation rate and embryo production in three breeds of sheep 显示文摘 | Picazo R A Cocero M L Barragan | 1996 | Theriogenology1996，41，1： | 1 |
| 11 | Renal failure and acquired hypothyroidism 显示文摘 | Del-Rfo Camacho G Tapia Ceballos L Picazo Angeltn B | 2003 | Pediatr Nephrol2003，18，3： | 1 |
| 12 | Effects of LH adminis- tration at the end of an FSH superovulatory regimen on ovulation rate and embryo production in three breeds of sheep 显示文摘 | Picazo R A Coeero M L Barragdn | 1996 | Theriogenology1996，45，5： | 1 |
| 13 | Alterations in GABAergic function following forced swimming stress显示文摘 | Briones-Aranda A Rocha L Picazo O | 2005 | Pharmacol Bioctlem Behav2005，80，3： | 1 |
| 14 | Effects of LH administration at the end of an FSH superovulatory regimen on ovulation rate and embryo production in three breeds of sheep显示文摘 | PICAZO R A COCERO M L BARRAGAN M L | 1996 | Theriogenology1996，45，5： | 1 |
| 15 | Effects of LH administration at the end of an FSH superovulatory regi-men on ovulation rate and embryo production in three breeds of sheep 显示文摘 | Picazo R A Cocero M L Barragdn | 1996 | Theriogenology1996，45，5： | 1 |
| 16 | Influence of cadmium and nickel on growth,net photosynthesis and carbohydrate distribution in rice plants显示文摘 | MOYA J L ROS R PICAZO I | 1993 | Photosynthesis Research1993，36，： | 1 |
| 17 | Renal failure and acquired hypothyroidism显示文摘 | Del G Tapia L Picazo B | 2003 | Pediatr Nephrol2003，18，3： | 1 |
| 18 | Influence of cadmium and nickel on growth, net photosynthesis and carbohydrate distribution in rice plants显示文摘 | Moya J L Ros R Picazo I | 1992 | Photosynthesis Research1992，36，： | 1 |
| 19 | Primary renal angiosarcoma:case report and review of the literature显示文摘 | Martinez-Pineiro L lopez-Ferrer P Picazo Ml | 1995 | Scand J Urol Nephrol1995，29，2： | 1 |
| 20 | Renal failure and acquired hypothyroidism 显示文摘 | del-Rio Camacho G Tapia Ceballos L Picazo Angelin B | 2003 | Pediatr Nephrol2003，18，29： | 1 |
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