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		题名	作者	年代	出处	被引量
	1	The cell polarity regu- lator hScrib controls ERK activation through a KIM site-de- pendent interaction 显示文摘	Nagasaka K Pim D Massimi P	2010	Oncogene2010，23，38：	1
	2	NOx removal from fluegas by an integrated physicochemical absorption and biological de-inartificial process显示文摘	Peter V D M Pim V D B Bram K	2005	Biotechnology and Bioengineering2005，90，4：	1
	3	Development and internal validation of the Comprehensive ALPPS Preoperative Risk Assessment(CAPRA)score:is the patient suitable for Associating Liver Partition and Portal vein ligation for Staged hepatectomy(ALPPS)?显示文摘Background:Preoperative patient selection in Associating Liver Partition and Portal vein ligation for Staged hepatectomy(ALPPS)is not always reliable with currently available scores,particularly in patients with primary liver tumor.This study aims to(I)to determine whether comorbidities and patients characteristics are a risk factor in ALPPS and(II)to create a score predicting 90-day mortality preoperatively.Methods:Thirteen high-volume centers participated in this retrospective multicentric study.A risk analysis based on patient characteristics,underlying disease and procedure type was performed to identify risk factors and model the Comprehensive ALPPS Preoperative Risk Assessment(CAPRA)score.A nonparametric receiver operating characteristic analysis was performed to estimate the predictive ability of our score against the Charlson Comorbidity Index(CCI),the age-adjusted CCI(aCCI),the ALPPS risk score before Stage 1(ALPPS-RS1)and Stage 2(ALPPS-RS2).The model was internally validated applying bootstrapping.Results:A total of 451 patients were included.Mortality was 14.4%.The CAPRA score is calculated based on the following formula:(0.1×age)−(2×BSA)+1(in the presence of primary liver tumor)+1(in the presence of severe cardiovascular disease)+2(in the presence of moderate or severe diabetes)+2(in the presence of renal disease)+2(if classic ALPPS is planned).The predictive ability was 0.837 for the CAPRA score,0.443 for CCI,0.519 for aCCI,0.693 for ALPPS-RS1 and 0.807 for ALPPS-RS2.After 1,000 cycles of bootstrapping the C statistic was 0.793.The accuracy plot revealed a cut-off for optimal prediction of postoperative mortality of 4.70.Conclusions:Comorbidities play an important role in ALPPS and should be carefully considered when planning the procedure.By assessing the patient’s preoperative condition in relation to ALPPS,the CAPRA score has a very good ability to predict postoperative mortality.	Ivan Capobianco Karl J.Oldhafer Mohammed-Hossein Fard-Aghaie Ricardo Robles-Campos Roberto Brusadin Henrik Petrowsky Michael Linecker Arianeb Mehrabi Katrin Hoffmann Jun Li Asmus Heumann Roberto Hernandez-Alejandro Mauro Enrique Tun-Abraham Elio Jovine Matteo Serenari Bergthor Bjornsson Per Sandström Ruslan Alikhanov Mikhail Efanov Paolo Muiesan Andrea Schlegel Thomas M.van Gulik Pim B.Olthof Gregor Alexander Stavrou Lina Maria Serna-Higuita Alfred Königsrainer Silvio Nadalin	2022	Hepatobiliary Surgery and Nutrition2022，11，1：	1
	4	Reoovery following stroke:The role of self-management education显示文摘	Elizabeth K Tara C Pim K		0，，03：	1
	5	Higher ambulatory bleed pres-sure relates to new cerebral mictobleeds 2-Year Follow-Upstudy in lacunar stroke patients 显示文摘	Pim K Robert J Rob P	2013	Stroke2013，44，4：	1
	6	Aerobic biodegradation studies of nonylpheuol ethoxylates in river water using liquid chromatographyelectrospray tandem mass spectrometry 显示文摘	Jonkers N Thomas P K and Pim De V	2001	Environ Sci Technol2001，35，：	1
	7	NOx removal from flue gas by an integrated process 显示文摘	Peter V D M Pim V D B Bram K	2005	Biotechnology and Bioengineering2005，90，4：	1
	8	Cloning and relational analysis of 15 novel fungal endoglucanases from family 12 glycosyl hydrolase显示文摘	FRITS G TIMOTHY F JAY P PIM V der K PIET V S LYD?IA D SCOTT D P	2002	Cur?rent Geneties2002，41，：	1
	9	Aerobic biodegradation studies of nonylphenol ethoxylates in river water using liquid chro- matography - electrospray tandem mass spectrometry 显示文摘	Jonkers N Thomas P K and Pim De V	2001	Environ Sci Technol2001，，35：	1
	10	NOx Removal fro Flue Gas by an Integrated Physiocherni- cal Absorption and Biological de-Nitrification Process 显示文摘	PETER V D M PIM V D C BMM K	2005	Bigtechnol and Bioengin2005，90，4：	1
	11	Identifieation of novel mutation sin FOXLZ associated with Premature ovarian failure显示文摘	HalTis SE Chand AL Winshi PIM Gersak K Aittomaki K Shelling AN	2002	Mol Hum Reprod2002，8，8：	1

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