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| 1 | Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response. | Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu | 2016 | World Journal of Gastrointestinal Oncology2016，8，9： | 3 |
| 2 | A morphometric study on the superficial palmar arch of the hand显示文摘 | O. Bilge Y. Pinar M. A. ?zer F. G?vsa | 2006 | Surgical and Radiologic Anatomy2006，，4： | 2 |
| 3 | Worst-case robust decisions for multi-period mean-variance portfolio optimization显示文摘 | Güpinar N Rustem B | 2007 | Euro-pean Journal of Operational Research2007，183，3： | 1 |
| 4 | 计算机控制的Ishihara色觉测试法(英文)显示文摘目的:研究经计算机控制的Ishihara测试法诊断色盲的可靠性及其与经典Ishihara测试法的一致性,计算机控制的Ishihara测试法的敏感性与特异性;并探讨该测试方法在检测先天性色盲或色弱中的潜在价值。方法:用两种方法测试104名大学生的色觉,年龄20~23岁(中位数21岁)。分别采用经计算机控制的Ishihara色板和经典的Ishihara打印色板显露法对个体色觉进行检查。通过上述两种不同的方法评价每个学生对颜色的感知能力,借此探讨计算机控制的Ishihara测试法的特异性,准确性以及与经典法的一致性。结果:本实验共检测到6位男性色盲患者和1位女性色盲患者。调查该女性学生的家族史,发现其母亲为色盲基因携带者,而其父亲为色盲患者。本实验中男性色盲患病率为13.6%(6/44),女性为1.7%(1/60);整个人群总的患病率为6.7%(7/104)。进行本试验前,这些学生并未意识到自己存在色觉功能缺陷。为探讨这两种方法的一致性,分别对色觉正常和患色盲的学生的测试结果进行比较。结果表明:两种实验方法的特异性及敏感性均为100%,一致性达到100%。结论:计算机控制的Ishihara测试法是数字调控性的,但有关色觉测试的基本概念没有改变。该法总的测试时间和误差计分都已标准化,与手动测试法相比有明显的优势;而且该法与被认为是'金标准'的经典测试法的一致性达到100%。这些特征表明,计算机控制的Ishihara测试法是一种新颖和可靠的方法。 | Nimet nay Gündogan Nezih Durmazlar Koray Gümüs Pinar Geyik zdemir | 2007 | 国际眼科杂志2007，7，5： | 1 |
| 5 | Phylogenetic 16srRNA analysis reverals the presence of complex andpartly unknown bacterial communities in Tito Bustillocave,Spain,and on its Palaeolithic paintings显示文摘 | Schabereiter-Gurtner C Saiz-Jimenez Pinar G et a1 | 2002 | Environ Microbiol2002，4，7： | 1 |
| 6 | Ahamira cave paleolithic paintings harbor partly unknnown bacterial communities显示文摘 | Schabereiter-Gurtner C Saiz-Jimenez C Pinar G | 2002 | FEMS Microbiology Letters2002，211，： | 1 |
| 7 | Phylogenetic 16S rRNA analysis reveals the presence of complex and partly unknown bacterial communities in Tito Bustillo cave, Spain, and on its palaeolithic paintings显示文摘 | Schabereiter-Gurtner C Saiz-Jimenez C Pinar G | 2002 | Environmental Microbiology2002，4，7： | 1 |
| 8 | The efficacy of preopoerative instruction in reducing anxiety following gyneoncologlcal surgery:a case control study 显示文摘 | Pinar G Kurt A Gungor T | 2011 | World journal of surgical oncology2011，9，1： | 1 |
| 9 | Phylogenetic 16S rRNA analysis reveals the presence of complex an partly unknown bacterial communities in Tito Bustillocave Spain,and on its palaeolithic paintings显示文摘 | Schabereiter-Gurtner C Saiz-Jimenez C Pinar G | 2002 | Environ Microbiol2002，4，7： | 1 |
| 10 | The relationship between social suppo and the level of anxiety,depres- sion, and quality of life of Turkish women with gyneco- logic cancer 显示文摘 | Pinar G Okdem S Buyukgonenc L | 2012 | Cancer Nuts2012，35，3： | 1 |
| 11 | Archaeal communities in two disparate deteriorated ancient wall paintings:detection,identification and temporal monitoring by denaturing gradient gel electrophoresis显示文摘 | Pinar G Saiz-Jimenez C Schabereiter-Gurtner C | 2001 | FEMS Microbiol Ecol2001，37，： | 1 |
| 12 | The relationship between social support and the level of anxiety, depression, and quality of life of turkish women with gynecologic cancer显示文摘 | Pinar G Okdem S Buyukgonenc L | 2012 | Cancer Nut2012，35，3： | 1 |
| 13 | In vitroantioxidant activity, cyclooxygenase-2, thioredoxin reductaseinhibition and DNA protection properties of Teucriumsandrasicum L显示文摘 | PINAR A S NURTEN O GULAY E G | 2015 | Industrial Crops and Products2015，74，： | 1 |
| 14 | Phylogenetic 16S rRNA analysis reveals the presence of complex and partly unknown bacterial communities in Tito Bustillocave, Spain, and on its palaeolithic paintings显示文摘 | Schabereiter-Gurtner C Saiz-Jimenez C Pinar G | 2002 | Environ Microbiol2002，4，7： | 1 |
| 15 | Robust localization of nodes and time-recursive tracking in sensor networks using noisy range measurements 显示文摘 | Pinar O Joao G Paulo O | 2011 | IEEE Transactions on Signal Processing2011，59，8： | 1 |
| 16 | White matter injuryafter cerebral ischemia in ovine fetuses 显示文摘 | Petersson K H Pinar H Stopa E G | 2002 | Pediatr Res2002，51，6： | 1 |
| 17 | The relationship between social support and the level of anxiety,depression,and quality of life of turkish women with gynecologic cancer显示文摘 | Pinar G Okdem S Buyukgonenc L | | 0，，03： | 1 |
| 18 | Fed-batch methanol feeding strategyfor recombinant protein production by Pichia patoris in the pres- ence of co-substrate sorbitol 显示文摘 | Eda C Pinar C Stephen G | 2009 | Yeast2009，26，： | 1 |
| 19 | Metabolic flux analysis for recombi- nant protein production by Pichia pastoris using dual carbon sources: effects of methanol feeding rate显示文摘 | Eda C Pinar C Stephen G | 2010 | Biotechnol Bioeng2010，105，2： | 1 |
| 20 | A 2-year aeropalynological survey of allergenic pollen in the atmosphere of Kastamonu,Turkey显示文摘 | Talip C Pinar NM Kerim G | 2012 | Aero- biologia2012，28，： | 1 |
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