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| 1 | Current role of spacers for prostate cancer radiotherapy显示文摘Radiotherapy is an established curative treatment method for prostate cancer. Optimal tumor control rates can only be achieved with high local doses,associated with a considerable risk of rectal toxicity. Apart from already widely adapted technical advances,as intensitymodulated radiation therapy,the application of spacers placed between the prostate and rectum has been increasingly used in the last years. Biodegradable spacers,including hydrogel,hyaluronic acid,collagen or an implantable balloon,can be injected or inserted in a short procedure under transrectal ultrasound guidance via a transperineal approach. A distance of about 1.0-1.5 cm is usually achieved between the rectum and prostate,excluding the rectal wall from the high isodoses. Several studies have shown well tolerated injection procedures and treatments. Apart from considerable reduction of rectal irradiation,a prospective randomized trial demonstrated a reduction of rectal toxicity after hydrogel injection in men undergoing prostate image-guided intensity-modulated radiation therapy. The results are encouraging for continuing evaluation in dose escalation,hypofractionation,stereotactic radiotherapy or re-irradiation trials in the future. | Michael Pinkawa | 2015 | World Journal of Clinical Oncology2015，6，6： | 2 |
| 2 | Stereotactic body radiation therapy (SBRT) for treatment of adrenal gland metastases from non-small cell lung cancer显示文摘 | Holy R Piroth M Pinkawa M | 2011 | Strahlenther Onkol2011，187，4： | 1 |
| 3 | Changes of dose delivery distribution within the first month after permanent interstitial brachytherapy for prostate cancer显示文摘 | Pinkawa M Gagel B Piroth MD | 2006 | Strahlenther Onkol2006，182，9： | 1 |
| 4 | Health-related quality of life after permanent I-125 brachytherapy and conformal external beam radiotherapy for prostate cancer-a matched-pair comparison显示文摘 | Pinkawa M Asadpour B Piroth M D | | 0，，02： | 1 |
| 5 | Prostate-specific antigen kinetics following external-beam radiotherapy and temporary (Ir-192) or permanent (I-125) brachytherapy for prostate cancer显示文摘 | Pinkawa M Piroth M D Holy R ctal | | 0，，01： | 1 |
| 6 | Dose-escalation using intensity-modulated radiotherapy for prostate cancer-evaluation of the dose distribution with and without 18 F-choline PET-CT detected simultaneous integrated boost显示文摘 | Pinkawa M Attieh C Piroth MD | | 0，，： | 1 |
| 7 | Intensity-modulated radiotherapy for prostate cancer implementing molecular imaging with 18 F-choline PET-CT to define a simultaneous integrated boost显示文摘 | Pinkawa M Holy R Piroth MD | | 0，，： | 1 |
| 8 | Erectile dysfunction after external beam radiotherapy for prostate cancer显示文摘 | Pinkawa M Gagel B Piroth M D etal | 2008 | Eur Urol2008，24，： | 1 |
| 9 | Stereotactic body radiation therapy (SBRT) for treatment of adrenal gland metas- tases from non-small cell lung cancer 显示文摘 | HOLY R PIROTH M PINKAWA M | 2011 | Strahlenther Onkol2011，187，4： | 1 |
| 10 | Postoperative radio- therapy of glioblastoma multiforme : analysis and critical as- sessment of different treatment strategies and predictive fac- tors 显示文摘 | Piroth MD Gagel B Pinkawa M | 2007 | Strahlenther Onko12007，183，12： | 1 |
| 11 | Prostate-specific antigen kinetics following external-beam radiotherapy and temporary(Ir-192)or permanent(I-125)brachytherapy for prostate cancer显示文摘 | Michael Pinkawa a Marc D Piroth a Richard Holy | 2010 | Radiotherapy and Oncology2010，96，1： | 1 |
| 12 | Factor analysis of the Expanded Prostate Cancer Index Composite(EPIC) in a patient group after primary(external beam radiotherapy and permanent iodine125 brachytherapy) and postoperative radiotherapy for prostate cancer显示文摘 | Volz-Sidiropoulou E Pinkawa M Fischedick K | 2008 | Curr Urol2008，2，： | 1 |
| 13 | Postoperative ra- diotherapy of glioblastoma muhiforme: analysis and critical assessent of different treatment strategies and predictive factors 显示文摘 | Piroth MD Gagel B Pinkawa M | 2007 | Strahlenther Onkol2007，183，12： | 1 |
| 14 | Dose-volume histogram evaluation of prone and supine patient position in external beam radiotherapy for cervical and endometrial cancer显示文摘 | PINKAWA M GAGEL B DEMIREL C | 2003 | Radiother Oncol2003，69，1： | 1 |
| 15 | Treatment of Locally Advanced Prostate Cancer: A Case Report and Narrative Review显示文摘 | Frank Peinemann Michael Pinkawa A. Marte T. J. Murtola T. Nomura S. Takahashi | 2012 | Case Reports in Urology2012，，： | 1 |
| 16 | Evaluation of source dis- placement and dose-volume changes after permanent prostate braehy- therapy with stranded seeds 显示文摘 | Pinkawa M Asadpour B Gagel B | 2007 | Radiother Oncol2007，84，2： | 1 |
| 17 | Prostate-specific antigen kinetics following external-beam radiotherapy and temporary (Ir-192) or permanent (I-125) brachytherapy for prostate cancer显示文摘 | Pinkawa M Piroth M D Holy R | 2010 | Radiother Oncol2010，96，1： | 1 |
| 18 | Postoperative radiotherapy of glioblastoma multiforme:analysis and critical assessment of different treatment strategies and predictive factors显示文摘 | Piroth MD Gagel B Pinkawa M | | 0，，12： | 1 |
| 19 | Dose-volume histogram evaluation of prone and supine patient position in external beam radiotherapy for cervical and endometrial cancer显示文摘 | Pinkawa M Gagel B Demirel C | 2003 | Radiother Oncol2003，69，1： | 1 |
| 20 | Prostate-specific antigen kinetics following external-beam radiotherapy and temporary (Ir-192) or permanent (I-125) brachytherapy for prostate cancer显示文摘 | Pinkawa M Piroth MD Holy R | 2010 | Radiother Oncol2010，96，1： | 1 |
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