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		题名	作者	年代	出处	被引量
	1	Cost-utility of molecular adsorbent recirculating system treatment in acute liver failure显示文摘AIM:To determine the short-term cost-utility of mo-lecular adsorbent recirculating system(MARS) treatment in acute liver failure(ALF).METHODS:A controlled retrospective study was conducted with 90 ALF patients treated with MARS from 2001 to 2005.Comparisons were made with a historical control group of 17 ALF patients treated from 2000 to 2001 in the same intensive care unit(ICU) specializing in liver diseases.The 3-year outcomes and number of liver transplantations were recorded.All direct liver disease-related medical expenses from 6 mo before to 3 years after ICU treatment were determined for 31 MARS patients and 16 control patients.The health-related quality of life(HRQoL) before MARS treatment was estimated by a panel of ICU doctors and after MARS using a mailed 15D(15-dimensional generic healthrelated quality of life instrument) questionnaire.The HRQoL,cost,and survival data were combined and the incremental cost/quality-adjusted life years(QALYs) was calculated.RESULTS:In surviving ALF patients,the health-related quality of life after treatmeant was generally high and comparable to the age-and gender-matched general Finnish population.Compared to the controls,the average cost per QALY was considerably lower in the MARS group(64 732€ vs 133 858€) within a timeframe of 3.5 years.The incremental cost of standard medical treatment alone compared to MARS was 10 928€,and the incremental number of QALYs gained by MARS was 0.66.CONCLUSION:MARS treatment combined with standard medical treatment for ALF in an ICU setting is more cost-effective than standard medical treatment alone.	Taru Kantola Suvi Mklin Anna-Maria Koivusalo Pirjo Rsnen Anne Rissanen Risto Roine Harri Sintonen Krister Hckerstedt Helena Isoniemi	2010	World Journal of Gastroenterology2010，16，18：	3
	2	Responses of biotransformation and antioxidant enzymes in lemna minor and oncorhynchus mykiss exposed simultaneously to hexachlorobenzene显示文摘	Sashwati R Pirjo L S Sirpa H	1995	Chemosphere1995，30，8：	1
	3	Quantitative real-time PCR detection of toxic nodularia cyanobacteria in the Baltic Sea显示文摘	Kerttu K Christina L Pirjo R W Jouni J Kaarina S	2007	Appl Environ Microbiol2007，73，：	1
	4	Sewage sludge electro-dewatering treatment--a review 显示文摘	Tuan P A Mika S Pirjo I	2012	Drying Technology2012，30，7：	1
	5	In a randomized placebo-controlled add-on study orlistat significantly reduced clozapine-induced constipation显示文摘	Evgeny Chukhin Pirjo Takala Helin? Hakko Mirjam Raidma Hanna Putkonen Pirkko R?s?nen Viacheslav Terevnikov Jan-Henry Stenberg Markku Eronen Grigori Joffe	2013	International Clinical Psychopharmacology2013，，2：	1
	6	Aggregation and deposition of engineered TiO2 nanoparticles in natural fresh and brackish waters显示文摘	Markus S Tiina M P Pirjo S	2011	Journal of Physics:Conference Series2011，304，1：	1
	7	A fish hepatoma cell line(PLHC-1)as a tool to study cytotoxicity and cyp1a induction properties of cellulose and wood chip extract显示文摘	Sirpa E H Mark E H Pirjo L S	1998	Chemosphere1998，36，14：	1
	8	Sewage sludge electro-dewa- tering treatment-A review 显示文摘	Tuan P A Mika S Pirjo I	2012	Drying Technol2012，30，7：	1
	9	Taurine attenuates D-[3H]aspartate release evoked by depolarization in ischemic corticostriatal slices显示文摘	Sm M Simo OS Pirjo S		0，，：	1
	10	Responses of biotransformation and antioxidant enzymes in lemna minor and oncorhynchus mykiss exposed simultaneously to hexachlorobenzens 显示文摘	Sasbwati R Pirjo L S Sirpa H	1995	Chemosphere1995，30，8：	1

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