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	题名	作者	年代	出处	被引量
1	Mnk kinase pathway: Cellular functions and biological outcomes显示文摘The mitogen-activated protein kinase(MAPK) interacting protein kinases 1 and 2(Mnk1 and Mnk2) play important roles in controlling signals involved in mRNA translation. In addition to the MAPKs(p38 or Erk), multiple studies suggest that the Mnk kinases can be regulated by other known kinases such as Pak2 and/or other unidentified kinases by phosphorylation of residues distinct from the sites phosphorylated by the MAPKs. Several studies have established multiple Mnk protein targets, including PSF, heterogenous nuclear ribonucleoprotein A1, Sprouty 2 and have lead to the identification of distinct biological functions and substrate specificity for the Mnk kinases. In this review we discuss the pathways regulating the Mnk kinases, their known substrates as well as the functional consequences of engagement of pathways controlled by Mnk kinases. These kinases play an important role in mRNA translation via their regulation of eukaryotic initiation factor 4E(eIF4E) and their functions have important implications in tumor biology as well as the regulation of drug resistance to anti-oncogenic therapies. Other studies have identified a role for the Mnk kinases in cap-independent mRNA translation, suggesting that the Mnk kinases can exert important functional effects independently of the phosphorylation of eIF4 E. The role of Mnk kinases in inflammation and inflammationinduced malignancies is also discussed.	Sonali Joshi Leonidas C Platanias	2014	World Journal of Biological Chemistry2014，5，3：	16
2	Are capecitabine and oxaliplatin (XELOX) suitable treatments for progressing low-grade and high-grade neuroendocrine tumours?显示文摘	Emilio Bajetta Laura Catena Giuseppe Procopio Sara Dosso Ettore Bichisao Leonardo Ferrari Antonia Martinetti Marco Platania Elena Verzoni Barbara Formisano Roberto Bajetta	2007	Cancer Chemotherapy and Pharmacology2007，，：	2
3	Phase Ⅰ-Ⅱ trial of erythropoietin in the treatment of cisplatin-associated anemia显示文摘	Miller CB Platanias LC Mills SR	1992	J Natl Cancer Inst1992，84，2：	1
4	Mechanisms of type-Ⅰ-and type-Ⅱ-interferon-mediated signalling显示文摘	Platanias LC		0，，05：	1
5	Growth suppressive cytokines and the AKT/mTOR pathway 显示文摘	Kroczynska B Kaur S Platanias LC	2009	Cytokine2009，48，12：	1
6	Targeting AMPK in the treatment of malignancies显示文摘	Vakana E Altman JK Platanias LC	2012	J Cell Bioehem2012，113，2：	1
7	Antivirai effectsof interferon-β are enhanced in the absence of the translational suppressor 4E-BP1 in myocarditis induced by Coxsackievirus B3 显示文摘	Burke JD Sonenberg N Platanias LC	2011	Antivir Ther2011，16，4：	1
8	The p38 mitogen-aetivated protein kinase path- way and its role in interferon signaling显示文摘	Platanias LC	2003	Pharmaeol Ther2003，98，2：	1
9	Mechanisms of type-I-and type-II-interferon-mediated signalling显示文摘	Platanias LC	2005	Nature reviews Immunology2005，，5：	1
10	Introduction: interferon signals: what is classical and what is nonclassical显示文摘	Platanias LC	2005	J Interferon Cy- tokine Res2005，25，12：	1
11	Interferons: mechanisms of action and clinical applications显示文摘	Parmar S Platanias LC	2003	Curr Opin Oncol2003，15，6：	1
12	Protein kinase C signalling in leukemia 显示文摘	Redig A J Platanias LC	2008	Leuk Lymphoma2008，49，7：	1
13	Mechanisms of type-I- and type- II- interferon- mediated signalling显示文摘	Platanias LC	2005	Nat Rev Immu- nol2005，5，5：	1
14	Mechanisms of type- I - and type- ]I -interferon- mediated signalling显示文摘	Platanias LC	2005	Nat Rev Immunol2005，5，5：	1
15	The p38 mitogen-activated protein kinase pathway and its role in interferon signaling显示文摘	Platanias LC	2003	Pharmaeol Ther2003，98，2：	1
16	Differential expression of estrogen receptors alpha and beta in the spinal cord during postnatal development:localization in glial cells显示文摘	Platania P Laureanti F Bellomo M	2003	Neuroendocrinol2003，77，5：	1
17	Targeting AMPK in the treat- ment of malignancies 显示文摘	Vakana E Altman JK Platanias LC	2012	J Cell Biochem2012，113，2：	1
18	Use of an elec- tronic metabolic monitoring form in a mental health service - a ret- rospective file audit显示文摘	Happell B Platania - Phung C Gaskin CJ	2016	BMC Psychiatry2016，16，1：	1
19	Bounded model checking of software using SMT solvers instead of SAT solvers显示文摘	ARMANDO A MANTOVANI J PLATANIA L	2009	International Journal on Software Tools for Technology Transfer2009，1，1：	1
20	Map kinase signaling pathways and hema-tologic malignancies显示文摘	Platanias LC	2003	Blood2003，101，12：	1

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