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| 1 | Vitamin D and autoimmune thyroid diseases显示文摘The role of vitamin D as an immune modulator has been emphasized in recent years,and low levels of the hormone were observed in several autoimmune diseases including multiple sclerosis and systemic lupus erythematosus.Vitamin D mediates its effect though binding to vitamin D receptor(VDR),and activation of VDR-responsive genes.While VDR gene polymorphism was found to associate with autoimmune thyroid diseases(AITDs),few studies examined levels of vitamin D in these patients and those that did yielded conflicting results.We therefore undertook to evaluate the levels of vitamin D in patients with AITDs compared to patients with non-AITDs and healthy controls.Serum vitamin D(25-OH)levels were measured in 50 patients with AITDs,42 patients with non-AITDs and 98 healthy subjects,utilizing the LIAISON chemiluminescence immunoassay(DiaSorin,Saluggia,Italy).VitaminD deficiency was designated at levels lower than 10 ng/ml.Antithyroid antibodies,thyroid functions and demographic parameters were evaluated in all patients.The prevalence of vitamin D deficiency was significantly higher in patients with AITDs compared with healthy individuals(72% versus 30.6%;P<0.001),as well as in patients with Hashimoto’s thyroiditis compared to patients with non-AITDs(79% versus 52%;P<0.05).Vitamin D deficiency also correlated to the presence of antithyroid antibodies(P=0.01)and abnormal thyroid function tests(P=0.059).Significantly low levels of vitamin D were documented in patients with AITDs that were related to the presence of anti thyroid antibodies and abnormal thyroid function tests,suggesting the involvement of vitamin D in the pathogenesis of AITDs and the advisability of supplementation. | Shaye Kivity Nancy Agmon-Levin Michael Zisappl Yinon Shapira Endre V Nagy Katalin Danko Zoltan Szekanecz Pnina Langevitz Yehuda Shoenfeld | 2011 | Cellular & Molecular Immunology2011,8,3: | 47 |
| 2 | The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights显示文摘 | Amir Abbas Samani Shoshana Yakar Derek LeRoith Pnina Brodt | 2007 | Endocrine Reviews2007,,1: | 6 |
| 3 | 基于暴露视角的城市健康空间公平性研究——以南京为例显示文摘儿童与老年人是城市健康问题中的弱势群体,在低步行性、高污染物暴露的城市空间中更容易受到影响健康的威胁。本文以南京为例,基于污染物暴露视角,在识别健康空间的基础上,探索儿童与老年人的空间分布与步行性及污染物暴露的比较关系,并进一步分析健康空间的公平性问题。研究发现,健康空间分布对不同年龄结构的人群没有明显的倾向性,儿童相比老年人面临更加严峻的健康环境问题。研究还发现,弱势群体有被资本排挤出健康空间的趋势。 | 陈曦 冯建喜 Pnina Plaut | 2018 | 城乡规划2018,,3: | 4 |
| 4 | Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity显示文摘 | Francisco J Quintana AR Pnina C | 2000 | J Immunol2000,165,11: | 1 |
| 5 | Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60- kDa heat shock protein autoimmunity 显示文摘 | Francisco J Quintana A Pnina RC | 2000 | J Immunol2000,165,11: | 1 |
| 6 | A global perspective on library association codes of ethics显示文摘 | Shachaf Pnina | 2005 | Library & Information Science Research2005,,27: | 1 |
| 7 | Deregulated Expression of Homeobox-Containing Genes, HOXB6, B8, C8, C9, and Cdx-1, in Human Colon Cancer Cell Lines显示文摘 | Ben-Zion Vider Amazia Zimber Eric Chastre Christian Gespach Marisa Halperin Pnina Mashiah Abraham Yaniv Arnona Gazit | 2000 | Biochemical and Biophysical Research Communications2000,,2: | 1 |
| 8 | ERP Modeling:A Comprehensive Approach显示文摘 | BOAZ GOLANY DOV DORI | 2003 | Information Systems2003,28,4: | 1 |
| 9 | Aligning an ERP System with Enterprise Requirements:An Object-process Based Approach显示文摘 | BOAZ GOLANY DOV DORI | 2005 | Computers in Industry2005,56,6: | 1 |
| 10 | High incidence of malignancies in patients with dermatomyositis and polymyositis: An 11 - year analysis显示文摘 | Pnina L Avi L | 1998 | Semin Arthritis Rheum1998,27,5: | 1 |
| 11 | Psychological intervention in cancer patients:a randomized study显示文摘 | Lea B Tami P Pnina E H | 2001 | Gener Hosp Psychi2001,23,5: | 1 |
| 12 | ERP modeling: a comprehensive approach显示文摘 | Boaz Golany Dov Dori | 2003 | Information System2003,28,: | 1 |
| 13 | Magneto-impedance in sandwiched film for magnetic sensor heads 显示文摘 | HIKA K PNINA LV MOHRI K | 1996 | IEEE Trans Magn1996,32,: | 1 |
| 14 | High incidence of mlinagancies in patients with dermatomyositis and polymyositis:an 11 year analysis显示文摘 | Carmit RM Pnina Avi L | 1998 | Semin Arthritis Rheum1998,27,: | 1 |
| 15 | Cultural diversity and information and communication technology impacts on global virtual teams: an exploratory study 显示文摘 | PNINA SHACHAF | 2008 | Information & Management2008,45,2: | 1 |
| 16 | ERP Modeling:a Comprehensive Approach显示文摘 | Pnina S Boaz G Dov D | 2003 | Information Systems2003,28,: | 1 |
| 17 | Psychological intervention in cancer patients: a randomized study显示文摘 | Lea Baider Tami Peretz Pnina Ever Hadani Uwe Koch | 2001 | General Hospital Psychiatry2001,,: | 1 |
| 18 | Functional inhibition of ras by S-trans, trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice显示文摘 | Jacob G Amon A Pnina K | 2002 | Circulation2002,105,20: | 1 |
| 19 | Psychological intervention in cancer patients:a randomized study显示文摘 | Lea B Tami P Pnina EH | | 0,,05: | 1 |
| 20 | 可再充电电池的最新进展显示文摘随着从笔记本电脑、掌上型电脑到蜂窝移动电话机等便携式电子 设备的迅速发展,为这些设备提供电源的可再充电电池已成为公众注意的中心。虽然大多数设计人员认为电池是相对的“低技术”,但电池却取得了不少技术突破,大大延长了工作寿命,明显提高了输出功率。在重量、容量、体积和成本必须充分优化的场合,忽视这些进展就会丧失某一设计获得成功的机遇,便携式电脑和无线电通信设备尤其是这样。 | Pnina Dan 剑欣 | 1997 | 电子产品世界1997,4,7: | 1 |