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| 1 | New Clues that May Link Osteoporosis to the Circulating Lipid Profile显示文摘Bone Mineral Density(BMD)is a gold standard for the diagnosis of osteoporosis and is also important in the assessment of fracture risk.Other risk factors have been identified that together make up fracture risk assessment tools such as FRAX.Another potential factor,circulating lipids,has been suggested because of reports linking statins to fracture risk reduction.We analyzed the lipid profile in a cohort of women diagnosed with postmenopausal osteoporosis based on bone density determination:610 women with osteoporosis(mean lumbar spine T-score-3.16±0.81,mean yrs.since menopause 15.79±8.9)were grouped according to age at evaluation(<50 years,51-60 years,61-70 years,>70 years),the presence/absence of a history of a fragility fracture,statin and/or antiresorptive drug use.There was no correlation between BMD and Body Mass Index(BMI:P>0.05,r2<0.02).However,when BMD was correlated with both BMI and the lipid profile(Triglycerides,Cholesterol,LDLc,HDLc),significant correlations were found in 5 cohorts:51-60 years with fractures(n=61,r2=0.14,P<0.01),61-70 years(n=201,r2=0.09,P<0.01)with fractures(n=88,r2=0.14,P<0.01)or without fractures(n=113,r2=0.24,P=0.02)and over 70 years(n=247,r2=0.11,P<0.01). | Catalina Poiana Valentin Radoi Mara Carsote John P. Bilezikian | 2013 | Bone Research2013，1，3： | 5 |
| 2 | Espresso coffee (EC) by POD : Study of thermal profile during extraction process and influence of water temperature on chemical-physical and sensorial properties 显示文摘 | D Albanese M Di Matteo M Poiana | 2009 | Food Research International2009，44，： | 1 |
| 3 | CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaction显示文摘 | Saggio I Gloaguen I Poiana G | 1995 | EMBO1995，14，13： | 1 |
| 4 | Giant adrenal cyst;case study 显示文摘 | Poiana C Carsote M Chirita C | 2010 | J Med Life2010，3，3： | 1 |
| 5 | The effect of long-term frozen storage on the nutraceutical compounds, antioxidant properties and color indices of different kinds of berries 显示文摘 | Poiana M A Moigradean D Raba D | 2010 | Journal of Food Agriculture & Environ- merit2010，8，1： | 1 |
| 6 | Update in endocrinology - primary hyperaldosteronism - from secondary hypertension towards metabolic syndrome and beyond显示文摘 | Trifanescu RA Poiana C | 2012 | Maedica (Buchar)2012，7，1： | 1 |
| 7 | Prospects for the use of the supercritical fluid extraction technique for bergamot fractions显示文摘 | Sicari V Mincione B | 1997 | Essenze Deriv Agrum1997，67，1： | 1 |
| 8 | Case study of appendiceal carcinoid during pregnancy 显示文摘 | Poiana C Carsote M Trifanescu R | 2012 | Journal of Medicine & Life2012，5，3： | 1 |
| 9 | CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaction显示文摘 | Saggio I Gloaguen I Poiana G | 1995 | EMBO J1995，14，： | 1 |
| 10 | Giant adrenal cyst:case study显示文摘 | Poiana C Carsote M Chirita C | | 0，，03： | 1 |
| 11 | Volatile components of peel oils of Italian and Japanese lemon and bergamot显示文摘 | Sawamura M Poiana M Kawamura A | | 0，，02： | 1 |
| 12 | The effect of long-term frozen storage on the nutraceutical compounds,antioxidant properties and color indices of different kinds of berries显示文摘 | Poiana M A Moigradean D Raba D | 2010 | Journal of Food Agriculture&Environment2010，8，1： | 1 |
| 13 | Reductive N-monoalkylation of primary aromatic amines显示文摘 | Verardo G Giumanini A G Strazzolini P Poiana M | 1993 | Synthesis1993，，1： | 1 |
| 14 | The dedifferentiation of neuroendocrine tumor metastases: myth or reality? 显示文摘 | Poiana C Neamllu MC Avramescu ET | 2013 | Rom J Morphol Embryol2013，54，1： | 1 |
| 15 | Supercritical carbon dioxide (SC-CO2) extraction of grapefruit flavedo显示文摘 | Poiana M Sicari V Mincione B | 1998 | Flavour Fragr1998，13，： | 1 |
| 16 | Extraction using enzymatic compounds in industrial plants and analytical characteristics of the oil显示文摘 | Castaldo A Casvone A Poiana M | 1997 | Riv Ital Sostance Grase1997，74，： | 1 |
| 17 | CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaetion显示文摘 | Saggio I Gloaguen I poiana G | 2007 | EMBO J2007，14，9： | 1 |
| 18 | Transcriptional regulation of adult neural stem/progenitor cells: tales from the subventricular zone显示文摘In rodents,well characterized neurogenic niches of the adult brain,such as the subventricular zone of the lateral ventricles and the subgranular zone of the hippocampus,support the maintenance of neural/stem progenitor cells(NSPCs)and the production of new neurons throughout the lifespan.The adult neurogenic process is dependent on the intrinsic gene expression signatures of NSPCs that make them competent for self-renewal and neuronal differentiation.At the same time,it is receptive to regulation by various extracellular signals that allow the modulation of neuronal production and integration into brain circuitries by various physiological stimuli.A drawback of this plasticity is the sensitivity of adult neurogenesis to alterations of the niche environment that can occur due to aging,injury or disease.At the core of the molecular mechanisms regulating neurogenesis,several transcription factors have been identified that maintain NSPC identity and mediate NSPC response to extrinsic cues.Here,we focus on REST,Egr1 and Dbx2 and their roles in adult neurogenesis,especially in the subventricular zone.We review recent work from our and other laboratories implicating these transcription factors in the control of NSPC proliferation and differentiation and in the response of NSPCs to extrinsic influences from the niche.We also discuss how their altered regulation may affect the neurogenic process in the aged and in the diseased brain.Finally,we highlight key open questions that need to be addressed to foster our understanding of the transcriptional mechanisms controlling adult neurogenesis. | Giancarlo Poiana Roberta Gioia Serena Sineri Silvia Cardarelli Giuseppe Lupo Emanuele Cacci | 2020 | Neural Regeneration Research2020，15，10： | 1 |
| 19 | Multiple endocrine neoplasiatype 2A: case report 显示文摘 | Paun DL Poiana C Petris R | 2013 | Chirurgia (Bucur)2013，108，6： | 1 |
| 20 | Detection of vegetable oils a- dulteration on the basis of fatty acids composition delerrained by RP-HPLC显示文摘 | Alexa E Poiana M Peev C | 2006 | Revista de chimie2006，57，： | 1 |
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