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| 1 | Primary hepatic carcinoid:A case report and literature review显示文摘Carcinoids are tumors derived from neuroendocrine cells and often produce functional peptide hormones.Approximately 54.5% arise in the gastrointestinal tract and frequently metastasize to the liver.Primary hepatic carcinoid tumors(PHCT) are extremely rare;only 95 cases have been reported.A 65-year-old man came to our attention due to occasional ultrasound findings in absence of clinical manifestations.His previous medical history,since 2003,included an echotomography of the dishomogeneous parenchymal area but no focal lesions.A computed tomography scan performed in 2005 showed an enhanced pseudonodular-like lesion of about 2 cm.Cholangio-magnetic resonance imaging identified the lesion as a possible cholangiocarcinoma.No positive findings were obtained with positron emission tomography.Histology suggested a secondary localization in the liver caused by a low-grade malignant neuroendocrine tumor.Immunohistochemistry was positive for anti chromogranin antibodies,Ki67 antibodies and synaptophysin.Octreoscan scintigraphy indicated intense activity in the lesion.Endoscopic investigations were performed to exclude the presence of extrahepatic neoplasms.Diagnosis of PHCT was established.The patient underwent left hepatectomy,followed by hormone therapy with sandostatine LAR.Two months after surgery he had a lymph nodal relapse along the celiac trunk and caudate lobe,which was histologically confirmed.The postoperative clinical course was uneventful,with a negative follow-up for hematochemical,clinical and radiological investigations at 18 mo post-surgery.Diagnosis of PHCT is based principally on the histopathological confi rmation of a carcinoid tumor and the exclusion of a non-hepatic primary tumor.Surgical resection is the recommended primary treatment for PHCT.Recurrence rate and survival rate in patients treated with resection were 18% and 74%,respectively. | Luigi Maria Fenoglio Sara Severini Domenico Ferrigno Giovanni Gollè Cristina Serraino Christian Bracco Elisabetta Castagna Chiara Brignone Fulvio Pomero Elena Migliore Ezio David Mauro Salizzoni | 2009 | World Journal of Gastroenterology2009，15，19： | 14 |
| 2 | Venous Lower-Limb Evaluation in Patients With Acute Pulmonary Embolism显示文摘 | Fulvio Pomero Chiara Brignone Cristina Serraino Sergio Panzone Christian Bracco Elena Migliore Paola Dalmasso Paolo Cavallo Perin Luigi Maria Fenoglio | 2011 | Southern Medical Journal2011，，6： | 2 |
| 3 | Spinal alignment evolution with age:A prospective gait analysis study显示文摘AIM To describe,using gait analysis,the development of spinal motion in the growing child.METHODS Thirty-six healthy children aged from 3 to 16 years old were included in this study for a gait analysis(9m-walk).Various kinematic parameters were recorded and analyzed such as thoracic angle(TA),lumbar angle(LA)and sagittal vertical axis(SVA).The kinetic parameters were the net reaction moments(N.m/kg)at the thoracolumbar and lumbosacral junctions.RESULTS TA and LA curves were not statistically correlated to the age(respectively,P=0.32 and P=0.41).SVA increased significantly with age(P<0.001).Moments in sagittal plane at the lumbosacral junction were statistically correlated to the age(P=0.003),underlining the fact that sagittal mechanical constraints at the lumbosacral junction increase with age.Moments in transversal plane at the thoracolumbar and lumbosacral junctions were statistically correlated to the age(P=0.0002and P=0.0006),revealing that transversal mechanical constraints decrease with age.CONCLUSION The kinetic analysis showed that during growth,a decrease of torsional constraint occurs while an increase of sagittal constraint is observed.These changes in spine biomechanics are related to the crucial role of the trunk for bipedalism acquisition,allowing stabilization despite lower limbs immaturity.With the acquisition of mature gait,the spine will mainly undergo constraints in the sagittal plane. | Sébastien Pesenti Benjamin Blondel Emilie Peltier Elke Viehweger Vincent Pomero Guillaume Authier Stéphane Fuentes Jean-Luc Jouve | 2017 | World Journal of Orthopedics2017，8，3： | 2 |
| 4 | Lumbosacral lordosis in fetalspine:genetic or mechanic parameter显示文摘 | Choufani E Jouve JL Pomero V | 2009 | Eur Spine J2009，18，9： | 1 |
| 5 | Ureaplasma and bronchopulmonary dys- plasia显示文摘 | Gancia P Delogu A Pomero G | 2014 | Early Hum Dev2014，90，1： | 1 |
| 6 | Venous lower-limb evalu- ation in patients with acute pulmonary embolism显示文摘 | Pomero F Brignone C Serraino C | 2011 | South Med J2011，104，6： | 1 |
| 7 | Worsening of hypertension in a pregnant woman with renal arteriovenous malformation: asuccessful superselective embolization after delivery 显示文摘 | Allione A Pomero F Valpreda S | 2003 | Clin Nephrol2003，60，3： | 1 |
| 8 | Fast accurate stereoradjog-raphic 3D:reconstruction of the spine using a combined geometricand statisticmodel显示文摘 | Pomero V Mitton D Laporte S | 2004 | Clin BiomeehBristol Avon2004，19，3： | 1 |
| 9 | Effects of protein kinase C inhibition and activation on proliferation and apoptosis of bovine retinal pericytes显示文摘 | Pomero F Allione A | 2003 | Diabetologia2003，46，3： | 1 |
| 10 | Chaotic Communication Based on the Particle in a Box Electronic Circuit显示文摘 | Pizolato J C Pomero MA Goncalves Neto L | 2008 | Circuits and Systems I:Regular Papers IEEE Transactions on2008，55，4： | 1 |
| 11 | Fast accurate stereora- diographic 3D-reconstruction of the spine using a combined geometric and statistic model 显示文摘 | Pomero V Mitton D Laporte S | 2004 | Clin Biomech (Bristol Avon)2004，19，3： | 1 |
| 12 | Worsening of renal arteriovenous embolization after delivery显示文摘 | Allione A Pomero F Valpreda S et hypertension malformation: m a pregnant a successful woman with superselective al | 2003 | Clin Nephrol2003，60，3： | 1 |
| 13 | Lumbosacral lordosis in fetal spine:genetic or mechanic parameter显示文摘 | Choufani E Jouve JL Pomero V | 2009 | Eur Spine J2009，18，9： | 1 |
| 14 | Epidemiology, clinical-treatment patterns and outcome in 256 hepatocellular carcinoma cases显示文摘AIM: To analyze the epidemiology, clinical characteristics, treatment patterns and outcome in hepatocellular carcinoma (HCC) patients. METHODS: We analyzed clinical, pathological and therapeutic data from 256 consecutive patients, examined at S. Croce Hospital in Cuneo-Piedmont, with a diagnosis of HCC between 30th June 2000 and 1st July 2010. We analyzed the hospital imaging database and examined all medical records, including the diagnosis code for HCC (155.0 according to the ICD-9M classification system), both for inpatients and outpatients, and discovered 576 relevant clinical records. After the exclusion of reports relating to multiple admissions for the same patient, we identified 282 HCC patients. Moreover, from this HCC series, we excluded 26 patients: 1 patient because of an alternative final diagnosis, 8 patients because of a lack of complete clinical data in the medical record and 17 patients because they were admitted to different health care facilities, leaving 256 HCC patients. To highlight possible changes in HCC patterns over the ten-year period, we split the population into two five-year groups, according to the diagnosis period: 30 th June 2000-30th June 2005 and 1st July 2005-1st July 2010. Patients underwent a 6-mo follow up. RESULTS: Two hundred and fifty-six HCC patients were included (male/female 182/74; mean age 70 years), 133 in the first period and 123 in the second. Hepatitis C virus (HCV) infection was the most common HCC risk factor (54.1% in the first period, 50.4% in the second;P = 0.63); in the first period, 21.8% of patients were alcoholics and 15.5% were alcoholics in the second period (P > 0.05); the non-viral/non-alcoholic etiology rate was 3.7% in the first period and 20.3% in the second period (P < 0.001). Child class A patients increased significantly in the second period (P < 0.001). Adjusting for age, gender and etiology, there was a significant increase in HCC surveillance during the second period (P = 0.01). Differences between the two periods were seen in tumor parameters: there was an increase in the number of unifocal HCC patients, from 53 to 69 (P = 0.01), as well as an increase in the number of cases where the HCC was < 3 cm [from 22 to 37 (P = 0.01)]. The combined incidence of stage Barcelona Clinic Liver Cancer 0 (very-early) and A (early) HCC was 46 (34.6%) between 2000-2005, increasing to 62 (50.4%) between 2005-2010 (P = 0.01). Of the patients, 62.4% underwent specific treatment in the first group, which increased to 90.2% in the second group (P < 0.001). Diagnosis period (P < 0.01), Barcelona-Clinic Liver Cancer stage (P < 0.01) and treatment per se (P < 0.05) were predictors of better prognosis; surveillance was not related to survival (P = 0.20).CONCLUSION: This study showed that, between 2000-2005 and 2005-2010, the number of HCV-related HCC decreased, non-viral/non alcoholic etiologies increased and of surveillance programs were more frequently applied. | Luigi Fenoglio Cristina Serraino Elisabetta Castagna Adele Cardellicchio Fulvio Pomero Maurizio Grosso Carlo Senore | 2013 | World Journal of Gastroenterology2013，19，21： | 1 |
| 15 | Fast accu-rate stereoradiographic 3D-reconstruction of the spine using acombined geometric and statistic model 显示文摘 | POMERO V MITTON D LAPORTE S | 2004 | Clin Biomech(Bristol Avon)2004，19，3： | 1 |
| 16 | Therapeutic hypothermia in the prevention of hypoxic-ischaemic encephalopathy: new categories to be enrolled 显示文摘 | Gancia P Pomero G | 2012 | J Matem Fetal Neonatal Med2012，254，： | 1 |
| 17 | Dehydroepi and rosterone protects bovine retinal capillary pericytes against glucose toxicity显示文摘 | Brignardello E Beltramo E Molinatti PA Gallo M Gatto V Pomero F | 1998 | Jendocrinol1998，158，： | 1 |
| 18 | The ocean's food web,a changing paradigm显示文摘 | Pomero L R | 1974 | Bio Science1974，，24： | 1 |
| 19 | Computer-as-sisted assessment of spinal sagittal plane radiographs 显示文摘 | Rajnics P Pomero V Templier A | 2001 | J Spinal Disord2001，14，2： | 1 |
| 20 | Fast accurate stereoradiographic 3D-reconstruction of the spine using a combined geometric and statistic model显示文摘 | Pomero V Mitton D Laporte S | 2004 | Clin Biomech (Bristol Avon)2004，19，3： | 1 |
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