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    题名 作者 年代 出处 被引量
1Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer Phenotype显示文摘Anna Abulí Xavier Bessa Juan Ramón González Clara Ruiz–Ponte Alejandro Cáceres Jenifer Mu?oz Victoria Gonzalo Francesc Balaguer Ceres Fernández–Rozadilla Dolors González Luisa de Castro Juan Clofent Luís Bujanda Joaquín Cubiella Josep M a Re?é Juan Diego 2010Gastroenterology2010,,3:2
2Can baseline ML Flow test results predict leprosy reactions? An investigation in a cohort of patients enrolled in the uniform multidrug therapy clinical trial for leprosy patients in Brazil显示文摘Background:The predictive value of the serology to detection of IgM against the Mycobacterium leprae-derived phenolic glycolipid-I/PGL-I to identify leprosy patients who are at higher risk of developing reactions remains controversial.Whether baseline results of the ML Flow test can predict leprosy reactions was investigated among a cohort of patients enrolled in The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil(U-MDT/CT-BR).Methods:This was a descriptive study focusing on the main clinical manifestations of leprosy patients enrolled in the U-MDT/CT-BR from March 2007 to February 2012 at two Brazilian leprosy reference centers.For research purposes,753 leprosy patients were categorized according to a modified Ridley-Jopling(R&J)classification and according to the development of leprosy reactions(reversal reaction/RR and erythema nodosum leprosum/ENL),and whether they had a positive or negative bacillary index/BI.Results:More than half of the patients(55.5%)reported leprosy reaction:18.3%(138/753)had a RR and 5.4%(41/753)had ENL.Leprosy reactions were more frequent in the first year following diagnosis,as seen in 27%(205/753)of patients,while 19%(142/753)developed reactions during subsequent follow-up.Similar frequencies of leprosy reactions and other clinical manifestations were observed in paucibacillary(PB)and multibacillary(MB)leprosy patients treated with U-MDT and regular MDT(R-MDT)(P=0.43 and P=0.61,respectively).Compared with PB patients,leprosy reactions were significantly more frequent in MB patients with a high BI,and more patients developed RR than ENL.However,RR and neuritis were also reported in patients with a negative BI.At baseline,the highest rate of ML Flow positivity was observed in patients with a positive BI,especially those who developed ENL,followed by patients who had neuritis and RR.Among reaction-free patients,81.9%were ML Flow positive,however,the differences were not statistically significant compared to reactional patients(P=0.45).Conclusions:MB and PB patients treated with R-MDT and U-MDT showed similar frequencies of RR and other clinical manifestations.Positive ML Flow tests were associated with MB leprosy and BI positivity.However,ML Flow test results at baseline showed limited sensitivity and specificity for predicting the development of leprosy reactions.Emerith Mayra Hungria Regiane Morillas Oliveira Gerson Oliveira Penna Lúcio Cartaxo Aderaldo Maria Araci de Andrade Pontes Rossilene Cruz Heitor de SáGonçalves Maria Lúcia Fernandes Penna Ligia Regina Franco Sansigolo Kerr Mariane Martins de Araújo Stefani Samira Bührer-Sékula 2016Infectious Diseases of Poverty2016,5,1:2
3Evolutionary conservation in the untranslated regions of actin mRNAs:DNA sequence of a human beta-actin cDNA显示文摘Ponte P Ng S Engel J 1984Nucl Acids Res1984,12,:1
4Composition and structural features of cell wall polysaccharides fromtomato fruits显示文摘SEYMOUR G B COLQUHOUN I J Du PONT M S 1990Phytochemistry1990,29,3:1
5Unified Method for the Prediction of Rain Attenuation in Satellite and Terrestrial Links显示文摘DA SILVA MELLO L PONTES M S 2012Journal of Microwaves Optoelectronics and Electromagnetic Applications2012,11,1:1
6Prediction of rain attenuation in terrestrial links using full rainfall rate distribution显示文摘SILLVA MELLO DA L A R PONTES M S SOUZA DE R M 2007Electronics Letters2007,43,25:1
7Global value chains: from governance to governmentality? 显示文摘GIBBON P PONTE S 2008Economy and Society2008,,3:1
8Polymeric precursor method to the synthesis of XWO4(X = Ca and Sr)thin films-structural,micro-structural and spectroscopic investigations显示文摘Pontes F M Galhiane M S Santos L S Petit L A Kataoka F P Mabuchi G H Longo E Zampieri M Pi-zani P S 2009Journal of Alloys and Compounds2009,477,12:1
9Headspace solid-phase microextraction-gas chromatography-quadrupole mass spectrometric methodology for the establishment of the volatile composition of Passiflora fruit species显示文摘Pontes M Marques J C Camara J S 2009Microchemical journal2009,93,1:1
10The mean seasonal cycle in sea level estimated from a data-constrained general circulation model显示文摘Vinogradov S V Ponte R M Heimbach P 2008Journal of Geophysical Research2008,113,:1
11Passive and Active Calibrator Characterization Using A Spaceborne SAR System Simulator显示文摘Moccia A Vetrella S Ponte S 1994IEEE Trans on Geoscience and Remote Sensing1994,32,3:1
12Heavy metals recovery from industrial wastewater using Taguchi method 显示文摘Kaminari N M S Schuhz D R Ponte M 2007Chemical Engineering Journal2007,126,23:1
13Headspacesolid phase microextraction-gas chromatography-quadrupole mass spectrometric methodology for the establishment of the volatile composition of Passiflora fruit species显示文摘PONTES M MARQUES J C CAMARA J S 2009Micro chemical Journal2009,93,1:1
14Sexual selection and the adaptive evolution of mammalian ejaculate proteins显示文摘Ramm S A Oliver P L Ponting C P Stockley P Emes R D 0,,01:1
15Lipase catalyzed esterifi-cation of glycidol in organic solvents显示文摘Martin J F Da Ponte M N Barreiros S 1993Biotechnol Bioeng1993,42,:1
16Interactions of captopril and verapamil on glucose tolerance and insulin action in an animal model of insulin resistance显示文摘Dal Ponte D B Fogt D L Jacob S 1998Metabolism1998,47,:1
17SiRNA and miRNA processing:New functions for cajal bodies显示文摘Pontes O Pikaard C S 2008Curr Opin Genet Dev2008,18,2:1
18Immunology of skin transplantation显示文摘Richters C D Hoekstra M J Pont J S 2005Clincs in Dermatology2005,23,:1
19Oily diatomite and galvanic wastes as raw materials for red ceramics fabrication显示文摘Mymrine V Ponte M J J S Ponte H A 2013Construction and Building Materials2013,,41:1
20A key to the world genera of the Coenosiini (Diptera,Muscidae,Coenosiinae)显示文摘Couri M S Pont A C 1999Studia diptero-logica1999,6,1:1
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