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| 1 | Assessment of vascular invasion in gastric cancer: A comparative study显示文摘AIM: To evaluate and compare detection of lymphatic and blood vessel invasion (LVI and BVI) by hematox-ylin-eosin (HE) and immunohistochemistry (IHC) in gastric cancer specimens, and to correlate with lymph node status. METHODS: IHC using D2-40 (a lymphatic endothelial marker) and CD34 (a pan-endothelial marker) was performed to study LVI and BVI in surgical specimens froma consecutive series of 95 primary gastric cancer cases. The results of the IHC study were compared with the detection by HE using McNemar test and kappa index. The morphologic features of the tumors and the presence of LVI and BVI were related to the presence of lymph node metastasis. A χ2 test was performed to obtain associations between LVI and BVI and other prognostic factors for gastric cancer. RESULTS: The detection rate of LVI was considerably higher than that of BVI. The IHC study identified eight false-positive cases and 13 false-negative cases for LVI, and 24 false-positive cases and 10 false-negative cases for BVI. The average Kappa value determined was moderate for LVI (k=0.50) and low for BVI (k=0.20). Both LVI and BVI were statistically associated with the presence of lymph node metastasis (HE: P=0.001, P=0.013, and IHC: P=0.001, P=0.019). The mor-phologic features associated with LVI were location of the tumor in the distal third of the stomach (P=0.039), Borrmann's macroscopic type (P=0.001), organ inva-sion (P=0.03) and the depth of tumor invasion (P=0.001). The presence of BVI was related only to the depth of tumor invasion (P=0.003). CONCLUSION: The immunohistochemical identification of lymphatic and blood vessels is useful for increasing the accuracy of the diagnosis of vessel invasion and for predicting lymph node metastasis. | Letícia Trivellato Gresta Ismael Alves Rodrigues-Júnior Lúcia Porto Fonseca de Castro Geovanni Dantas Cassali Mnica Maria Demas lva-res Cabral | 2013 | World Journal of Gastroenterology2013，19，24： | 8 |
| 2 | Mechanochemical synthesis of hercynite显示文摘 | Pablo M. Botta Esteban F. Aglietti José M. Porto López | 2002 | Materials Chemistry and Physics2002，，1： | 2 |
| 3 | Competition between fusion-evaporation and multifragmentation in central collisions in ^(58)Ni+^(48)Ca at 25A MeV显示文摘The experimental data concerning the58Ni+48Ca reaction at Elab(Ni)=25A MeV,collected by using the CHIMERA 4π device,have been analyzed in order to investigate the competition among different reaction mechanisms for central collisions in the Fermi energy domain.As a main criterion for centrality selection we have chosen the flow angle(flow) method,making an event-by-event analysis that considers the shape of events,as it is determined by the eigenvectors of the experimental kinetic-energy tensor.For the selected central events(flow >60°) some global variables,good to characterize the pattern of central collisions have been constructed.The main features of the reaction products were explored by using different constraints on some of the relevant observables,like mass and velocity distributions and their correlations.Much emphasis was devoted,for central collisions,to the competition between fusion-evaporation processes with subsequent identification of a heavy residue and a possible multifragmentation mechanism of a well defined(if any) transient nuclear system.Dynamical evolution of the system and pre-equilibrium emission were taken into account by simulating the reactions in the framework of transport theories.Different approaches have been envisaged(dynamical stochastic BNV calculations + sequential SIMON code,QMD,CoMD,etc.).Preliminary comparison of the experimental data with BNV calculations shows reasonable agreement with the assumption of sequential multifragmentation emission in the mass region of IMFs close to the heavy residues.Possible deviations from sequential processes were found for those IMFs in the region of masses intermediate between the mass of heavy residues and the mass of light IMFs.Further simulations are in progress.The experimental analysis will be enriched also by information obtained inspecting the IMF-IMF correlation function,in order to elucidated the nature of space-time decay property of the emitting source associated with events having the largest IMF multiplicity. | FRANCALANZA L ABBONDANNO U AMORINI F BARLINI S BINI M BOUGAULT R BRUNO M CARDELLA G CASINI G AGOSTINO M D' De FILIPPO V De SANCTIS J GERACI E GIUSSANI A GRAMEGNA F GUIOT B KRAVCHUK V La GUIDARA E LANZALONE G Le NEINDRE N MAIOLINO C MARINI P MORELLI L OLMI A PAGANO A PAPA M PIANTELLI S PIRRONE S POLITI G POGGI G PORTO F RUSSOTTO P RIZZO F VANNINI G VANNUCCI L | 2013 | Nuclear Science and Techniques2013，24，5： | 2 |
| 4 | Analysis of o- mega 3 fatty acid in natural and enrich chicken eggs by capillary zone electrophoresis 显示文摘 | Porto B L Souza M N Oliveira M A | 2011 | Analytical Sciences2011，27，5： | 1 |
| 5 | Optimal location of control valves in pipe networks by genetic algorithm显示文摘 | REIS L F R PORTO R M | 1997 | ASCE Journal of Water Resources Planning and Management1997，123，6： | 1 |
| 6 | Performance of low-cost ejectors 显示文摘 | Neto I E L Porto R D M | 2004 | Journal of Irrigation and Drainage Engineering2004，130，2： | 1 |
| 7 | Finding Approximate Palindromes in Strings 显示文摘 | Porto A H L Barbosa V C | 2002 | Pattern Recognition2002，35，11： | 1 |
| 8 | Proton magnetic resonance spectroscopy in childhood brainstem lesions 显示文摘 | Porto L Hattingen E Pilatus U | 2007 | Childs Nerv Syst2007，23，3： | 1 |
| 9 | Optimal location of control valves in pipe networks by genetic algorithm显示文摘 | Reis L F R Porto R M Chaudhry F H | 1997 | Water Resource Planning Management1997，123，6： | 1 |
| 10 | Microbial reduction of cyclohexanones显示文摘 | de Conti R M Porto A L M Augusto J | 2001 | Journal of Molecular Catalysis B:Enzymatic2001，11，4： | 1 |
| 11 | Extractive cultivation of xylanase by Penicillium janthinellum in a poly(ethylene glycol)/cashew-nut tree gum aqueous two-phase system显示文摘 | Oliveira L A Barros N B Porto A L | 2004 | Biotechnol Prog2004，20，6： | 1 |
| 12 | Accelerated Myelination associ- ated with venous congestion显示文摘 | Porto L Kieslich M Yan B | 2006 | Eur Radiol2006，16，4： | 1 |
| 13 | Liquid - liquid extraction of proteases from fermented broth by PEG/citrate aqueous two-phase system 显示文摘 | Porto T S Silva G M M Porto C S Cavalcanti M T H Neto B B Lima F J L Converti A Porto A L F Pessoa J A | 2008 | Chemical Engineering and Processing2008，47，4： | 1 |
| 14 | Analysis of open CNC architecture for machine tools 显示文摘 | Asato O L Kato E R R Inamasu R Y Porto A J V | 2002 | Revista Brasileira de Ciencias Mecanicas/Journal of the Brazilian Society of Mechanical Sciences2002，24，3： | 1 |
| 15 | Mechanical forces induce scar remodeling : study in non-pressure-treated versus pressure-treated hypertrophic scars显示文摘 | Costa A M Peyrol S Porto L C | 1999 | Am J Pathol1999，155，5： | 1 |
| 16 | Early changes induced by short-term low-dose cadmium exposure in rat ventral and dorsolateral prostates[J3显示文摘 | Laeorte L M Delella F K Porto Amorim E M | | 0，，11： | 1 |
| 17 | Electroplastic effect in cop- per subjected to low density electric current显示文摘 | Silveira V L A Porto M F S | 1981 | Scripta Metal1981，15，8： | 1 |
| 18 | Granuh:ytie sarcoma in children 显示文摘 | Porto L Kieslieh M Schwabe D | 2004 | Neuroradiology2004，46，： | 1 |
| 19 | Differentiation between high and low grade tumours in paediatric patients by using appar- ent diffusion coefficients显示文摘 | Porto L Jurcoane A Schwabe D | 2013 | Eur J Paediatr Neurol2013，17，3： | 1 |
| 20 | Batch fermentation model of propionic acid production by Propionibacterium acidipropionici in different carbon sources显示文摘 | CORAL J KARP S PORTO DE SOUZA VANDENBERGHE L | 2008 | Appl Biochem Biotechnol2008，151，： | 1 |
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