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| 1 | Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer disease显示文摘 | R Duara D A. Loewenstein E Potter J Appel M T. Greig R Urs Q Shen A Raj B Small W Barker E Schofield Y Wu H Potter | 2008 | Neurology2008，，24： | 2 |
| 2 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013，19，21： | 2 |
| 3 | Abnormal liver chemistries as a predictor of COVID-19 severity and clinical outcomes in hospitalized patients显示文摘BACKGROUND Abnormal liver chemistries are common findings in patients with Coronavirus Disease 2019(COVID-19).However,the association of these abnormalities with the severity of COVID-19 and clinical outcomes is poorly understood AIM We aimed to assess the prevalence of elevated liver chemistries in hospitalized patients with COVID-19 and compare the serum liver chemistries to predict the severity and in-hospital mortality.METHODS This retrospective,observational study included 3380 patients with COVID-19 who were hospitalized in the Johns Hopkins Health System(Baltimore,MD,United States).Demographic data,clinical characteristics,laboratory findings,treatment measures,and outcome data were collected.Cox regression modeling was used to explore variables associated with abnormal liver chemistries on admission with disease severity and prognosis RESULTS A total of 2698(70.4%)had abnormal alanine aminotransferase(ALT)at the time of admission.Other more prevalent abnormal liver chemistries were aspartate aminotransferase(AST)(44.4%),alkaline phosphatase(ALP)(16.1%),and total bilirubin(T-Bil)(5.9%).Factors associated with liver injury were older age,Asian ethnicity,other race,being overweight,and obesity.Higher ALT,AST,T-Bil,and ALP levels were more commonly associated with disease severity.Multivariable adjusted Cox regression analysis revealed that abnormal AST and T-Bil were associated with the highest mortality risk than other liver injury indicators during hospitalization.Abnormal AST,T-Bil,and ALP were associated with a need for vasopressor drugs,whereas higher levels of AST,T-Bil,and a decreased albumin levels were associated with mechanical ventilation CONCLUSION Abnormal liver chemistries are common at the time of hospital admission in COVID-19 patients and can be closely related to the patient’s severity and prognosis.Elevated liver chemistries,specifically ALT,AST,ALP,and T-Bil levels,can be used to stratify risk and predict the need for advanced therapies in these patients. | Arunkumar Krishnan Laura Prichett Xueting Tao Saleh A Alqahtani James P Hamilton Esteban Mezey Alexandra T Strauss Ahyoung Kim James J Potter Po-Hung Chen Tinsay A Woreta | 2022 | World Journal of Gastroenterology2022，28，5： | 2 |
| 4 | Freezing point depression of aqueous sodium chloride solutions 显示文摘 | Potter R W Clynne M A Brown D L | 1978 | Economic Geology1978，72，： | 1 |
| 5 | The purification of mouse monoclonal antibodies from ascitic fluid显示文摘 | Neoh SH Gordon C Potter A | 1986 | J Immunol Methods1986，91，2： | 1 |
| 6 | 查看详情显示文摘 | Potter A R Baker R T | | 0，，19： | 1 |
| 7 | Propofol infusion in children:when does ananesthetic tool become an intensive care liability 显示文摘 | WOLF A R POTTER F | 2004 | PediatricAnesthesia2004，15，6： | 1 |
| 8 | Estrogen and insulin-like growth factor- I ( IGF- I ) independently down-regulate critical repressors of breast cancer growth 显示文摘 | Casa A J Potter AS Malik S | 2012 | Breast Cancer Res Treat2012，132，1： | 1 |
| 9 | Review of clinical cor- relates of PSO sensory gating abnormalities in patients with schizo- phrenia 显示文摘 | Potter D Summmeffelt A Gold JM | 2006 | Schizophr Bu112006，32，： | 1 |
| 10 | Salmonella vaccines in poultry: past, present and future显示文摘 | Desin T S K6ster W Potter A A | 2013 | Expert Rev Vaccines2013，12，1： | 1 |
| 11 | The engi- neering aspects of automated prepreg Iayupt History, present and future显示文摘 | LUKASZEWICZ J A WARD C POTTER K | 2012 | Composites Part B: Engineering2012，43，2： | 1 |
| 12 | Estimation of global biogeochemical controls and seasonality in soil methane consump- tion 显示文摘 | Potter C S Davidson E A Verchot L V | 1996 | Chemosphere1996，32，： | 1 |
| 13 | Effect of monensin on feed efficiency of feedlot cattle显示文摘 | Cooley C O Potter E L | 1976 | J Anim Sci1976，，43： | 1 |
| 14 | Vegetation effects on fecal bacteria, BOD, and suspended solid removal in constructed wetlands treating domestic wastewater显示文摘 | Karathanasis A D Potter C L Coyne M S | 2003 | Ecological Engineering2003，20，2： | 1 |
| 15 | Disturbances in peripheral blood B cell subpopulations in autoimmune patients 显示文摘 | Potter KN Mockridge Cl Rahman A | 2002 | Lupus2002，11，12： | 1 |
| 16 | Vegetables, fruit, and cancer prevention: a review显示文摘 | Steinmetz K A Potter J D | 1996 | Journal American Diet Association1996，96，10： | 1 |
| 17 | Characterization of 14 microsatellite markers for genetic analysis and cultivar identification of walnut显示文摘 | Dangl GS Woeste K Aradhya MK Koehmstedt A simon C Potter D Leslie CA.McGranahan G | | 0，，： | 1 |
| 18 | Phagocyte-derived reactive oxygen species do not influence the progression of murine blood-stage malaria infections显示文摘 | Potter SM Mitchell A J Cowden WB | 2005 | Infect Immun2005，73，8： | 1 |
| 19 | Genotyping of peach and nectarine cultivars with SSR and SRAP molecular markers显示文摘 | Riaz A Potter D Stephen M | 2004 | Jouranal of American Society Horticultural Science2004，129，： | 1 |
| 20 | Cooperative co-evolution:An architecture for evolving co-adapted subcomponents显示文摘 | Potter M A De Jong K A | 2000 | Evolutionary Computation2000，8，1： | 1 |
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