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| 1 | 肠道微生态失调与高血压的关系显示文摘新出现的证据表明,肠道菌群是维持生理动态平衡的关键,该研究旨在验证微生态失衡的肠道菌群与高血压相关这一假设,因为遗传、环境和膳食因素对肠道菌群和血压有很大影响。方法:从2种高血压模型大鼠和一个小队列患者人群的粪便样本中提取细菌DNA,用于细菌基因组的分析. | 刘莉 叶鹏 Yang T Santisteban MM Rodriguez V Li E Ahmari N Carvajal JM Zadeh M Gong M Qi Y Zubcevic J Sahay B Pepine CJ Raizada MK Mohamadzadeh M | 2015 | 中华高血压杂志2015，23，5： | 4 |
| 2 | Role of observation of live cases done by Japanese experts in the acquisition of ESD skills by a western endoscopist显示文摘AIM:To evaluate the role of observation of experts performing endoscopic submucosal dissection(ESD)in the acquisition of ESD skills.METHODS:This prospective study is documenting the learning curve of one Western endoscopist.The study consisted of three periods.In the first period(preobservation),the trainee performed ESDs in animal models in his home institution in the United States.The second period(observation)consisted of visit to Japan and observation of live ESD cases done by experts.The observation of cases occurred over a 5-wk period.During the third period(post-observation),the trainee performed ESD in animal models in a similar fashion as in the first period.Three animal models were used:live40-50 kg Yorkshire pig,explanted pig stomach model,and explanted pig rectum model.The outcomes from the ESDs done in the animal models before and after observation of live human cases(main study intervention)were compared.Statistical analysis of the data included:Fisher’s exact test to compare distributions of a categorical variable,Wilcoxon rank sum test to compare distributions of a continuous variable between the two groups(pre-observation and post-observation),and Kruskal-Wallis test to evaluate the impact of lesion location and type of model(ex-vivo vs live pig)on lesion removal time.RESULTS:The trainee performed 38 ESDs in animal model(29 pre-observation/9 post-observation).The removal times post-observation were significantly shorter than those pre-observation(32.7±15.0 min vs 63.5±9.8 min,P<0.001).To minimize the impact of improving physician skill,the 9 lesions post-observation were compared to the last 9 lesions pre-observation and the removal times remained significantly shorter(32.7±15.0 min vs 61.0±7.4 min,P=0.0011).Regression analysis showed that ESD observation significantly reduced removal time when controlling for the sequence of lesion removal(P=0.025).Furthermore,it was also noted a trend towards decrease in failure to remove lesions and decrease in complications after the period of observation.This study did not find a significant difference in the time needed to remove lesions in different animal models.This finding could have important implications in designing training programs due to the substantial difference in cost between live animal and explanted organ models.The main limitation of this study is that it reflects the experience of a single endoscopist.CONCLUSION:Observation of experts performing ESD over short period of time can significantly contribute to the acquisition of ESD skills. | Peter V Draganov Myron Chang Roxana M Coman Mihir S Wagh Qi An Takuji Gotoda | 2014 | World Journal of Gastroenterology2014，20，16： | 3 |
| 3 | The angiotensin - converting enzyme 2/angiogenesis - (1 -7 )/Mas axis confers cardiopulmo- nary protection against lung fibrosis and pulmonary hypertension 显示文摘 | Shenoy V Ferreira A J Qi Y | 2010 | Am J Respir Ctit Care2010，182，8： | 1 |
| 4 | Prostaglandin E2 increases bone strength in intact rats and in ovariectomised rats with established osteopenia显示文摘 | Ke H Z Shen V W Qi H | 1998 | Bone1998，23，： | 1 |
| 5 | The protozoan parasite Toxoplasma gondii targets proteins to dense granules and the vacuolarspace using both conserved and unusual mechanisms显示文摘 | Karsten V Qi H Beckers CJ | 1998 | J Cell Biol1998，141，： | 1 |
| 6 | An ef- ficient Agrobacterium-mediated transient transforma- tion of Arabidopsis 显示文摘 | Kenichi Tsuda Yiping Qi Le V Nguyen | 2012 | The Plant Journal2012，69，： | 1 |
| 7 | Multiple-site labeling of proteins with unnatural amino acids显示文摘 | Loscha K V Herlt A J Qi R | 2012 | Angew Chem Int Ed2012，51，9： | 1 |
| 8 | ACE2,a promising therapeutic target for pulmonary hypertension显示文摘 | Shenoy V Qi Y Katovich MJ | 2011 | Curr Opin Pharmacol2011，11，2： | 1 |
| 9 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 10 | Associations of coagulation factor V Leiden and prothrombin G20210A mutations with Budd-Chiari syn- drome andporta! vein thrombosis: a systematic review and meta-analy- sis 显示文摘 | Qi x Ren W De Stefano V | 2014 | Clin Gastroenterol Hepatol2014，12，18： | 1 |
| 11 | Methylenetetrahydrofolate reductase C677T gene mutation and hyperhomoeysteinemia in Budd-Chiari syndrome and portal vein thrombosis: a systematic review and meta-analysis of observational studies 显示文摘 | Qi x Yang z De Stefano V | 2014 | Hepatol Res2014，，： | 1 |
| 12 | ACE2,a Promising therapeutic target for pulmonary hypertension显示文摘 | Shenoy V Qi Y Katovich MJ | 2011 | Curr Opin Pharmacol2011，11，2： | 1 |
| 13 | Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR显示文摘 | Kren V Qi N Krenova D | 2001 | Hypertension2001，37，： | 1 |
| 14 | Coordinate gene expression patterns during osteoblast maturation and retinoic acid treatment of MC3T3-E1 cells 显示文摘 | Kitching R Qi S Li V | 2002 | J Bone Miner Metab2002，20，5： | 1 |
| 15 | Heterogeneity of neuroblastoma cell lines in insulin-like growth factor 1 receptor/Akt pathway-mediat- ed cell proliferative responses显示文摘 | Qi L Toyoda H Shankar V | 2013 | Cancer Science2013，104，9： | 1 |
| 16 | Characterization and classification of tumor lesions using computerized fractal-based texture analysis and support vector machines in digital marnmograms显示文摘 | GUO Qi SHAO Jia-qing Ruiz V F | 2009 | International Journal of Computer Assisted Radiology and Surgery2009，4，1： | 1 |
| 17 | A linear time algorithm forcomputing exact Euclidean distance transforms of binaryimages in arbitrary dimensions 显示文摘 | Maurer C R Qi R Raghavan V | 2003 | IEEE Transactions onPattern Analysis and Machine Intelligence2003，25，2： | 1 |
| 18 | ACE2,a promising therapeutic target for pulmonary hypertension显示文摘 | Shenoy V Qi Y Katovich MJ Raizada MK | | 0，，： | 1 |
| 19 | ACE2, a promisingtherapeutic target for pulmonary hypertension 显示文摘 | Shenoy V Qi Y Katovich MJ | 2011 | Curr OpinPharmacol2011，11，2： | 1 |
| 20 | The angiotensin-converting enzyme 2/angiogene- sis-( 1-7 )/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension 显示文摘 | Shenoy V Ferreira A J Qi Y Fraga-Silva RA Diez-Freire C Dooies A | 2010 | Am J Respir Crit Care Med2010，1828，： | 1 |
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