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| 1 | Status monitoring and health assessment of Luhuitou fringing reef of Sanya, Hainan, China显示文摘The monitoring survey and health assessment for benthic community were carried out in Luhuitou fringing reef of Sanya, Hainan, China in 2002. Monitoring survey included manta tow, line intercept transect, video transect and digital photograph. The mean live coral cover was 23.40%. Comparison of used monitoring methods showed that video transect can replace line intercept transect, and 50 m transect is better than 20 m transect in uneven coral region. Survey data and comparison with previous research work showed that Luhuitou fringing reef has been damaged severely and has a general declining trend with live coral cover from about 85% in the 1960s down to 20% in 2004, but it still has quite high biodiversity and therefore has special protection value. Main factors of Luhuitou fringing reef declining were human activities including reef rock digging and curios collecting, destructive fishing, sediment and pollutant from coastal land, and recent marine aquaculture. Only strengthening integrated management can reach improvement and restoration of Luhuitou declining coral reef ecosystem. | ZHANG Qiaomin SHI Qi CHEN Gang FONG T C W WONG D C C HUANG Hui WANG Hankui ZHAO Meixia | 2006 | Chinese Science Bulletin2006，51，B12： | 15 |
| 2 | Immune responses against SARS-coronavirus nucleocapsid protein induced by DNA vaccine显示文摘 | Zhao P Cao J Zhao LJ Ke JS Pan W Ren H Yu JG Qi ZT | 2005 | 第二军医大学学报2005，26，10： | 12 |
| 3 | Multiphase computed tomography radiomics of pancreatic intraductal papillary mucinous neoplasms to predict malignancy显示文摘BACKGROUND Intraductal papillary mucinous neoplasms(IPMNs)are non-invasive pancreatic precursor lesions that can potentially develop into invasive pancreatic ductal adenocarcinoma.Currently,the International Consensus Guidelines(ICG)for IPMNs provides the basis for evaluating suspected IPMNs on computed tomography(CT)imaging.Despite using the ICG,it remains challenging to accurately predict whether IPMNs harbor high grade or invasive disease which would warrant surgical resection.A supplementary quantitative radiological tool,radiomics,may improve diagnostic accuracy of radiological evaluation of IPMNs.We hypothesized that using CT whole lesion radiomics features in conjunction with the ICG could improve the diagnostic accuracy of predicting IPMN histology.AIM To evaluate whole lesion CT radiomic analysis of IPMNs for predicting malignant histology compared to International Consensus Guidelines.METHODS Fifty-one subjects who had pancreatic surgical resection at our institution with histology demonstrating IPMN and available preoperative CT imaging were included in this retrospective cohort.Whole lesion semi-automated segmentation was performed on each preoperative CT using Healthmyne software(Healthmyne,Madison,WI).Thirty-nine relevant radiomic features were extracted from each lesion on each available contrast phase.Univariate analysis of the 39 radiomics features was performed for each contrast phase and values were compared between malignant and benign IPMN groups using logistic regression.Conventional quantitative and qualitative CT measurements were also compared between groups,viaχ2(categorical)and Mann Whitney U(continuous)variables.RESULTS Twenty-nine subjects(15 males,age 71±9 years)with high grade or invasive tumor histology comprised the'malignant'cohort,while 22 subjects(11 males,age 70±7 years)with low grade tumor histology were included in the'benign'cohort.Radiomic analysis showed 18/39 precontrast,19/39 arterial phase,and 21/39 venous phase features differentiated malignant from benign IPMNs(P<0.05).Multivariate analysis including only ICG criteria yielded two significant variables:thickened and enhancing cyst wall and enhancing mural nodule<5 mm with an AUC(95%CI)of 0.817(0.709-0.926).Multivariable post contrast radiomics achieved an AUC(95%CI)of 0.87(0.767-0.974)for a model including arterial phase radiomics features and 0.834(0.716-0.953)for a model including venous phase radiomics features.Combined multivariable model including conventional variables and arterial phase radiomics features achieved an AUC(95%CI)of 0.93(0.85-1.0)with a 5-fold cross validation AUC of 0.90.CONCLUSION Multi-phase CT radiomics evaluation could play a role in improving predictive capability in diagnosing malignancy in IPMNs.Future larger studies may help determine the clinical significance of our findings. | Stuart L Polk Jung W Choi Melissa J McGettigan Trevor Rose Abraham Ahmed Jongphil Kim Kun Jiang Yoganand Balagurunathan Jin Qi Paola T Farah Alisha Rathi Jennifer B Permuth Daniel Jeong | 2020 | World Journal of Gastroenterology2020，26，24： | 5 |
| 4 | Small interfering RNA inhibits SARS-CoV nucleocapsid gene expression in cultured cells and mouse muscles显示文摘 | Zhao P Qin ZL Ke JS Lu Y Liu M Pan W Zhao LJ Cao J Qi ZT | 2005 | 第二军医大学学报2005，26，10： | 4 |
| 5 | Intense single-band red upconversion emission in BiOCl:Er3+ layered semiconductor via co-doping Ho3+显示文摘Exploring a new tuning way to facilely realize single-band red emission in trivalent rare-earth ions(RE3+) doped upconversion(UC) materials is still desirable.In this work,the intense single-band red emission is achieved by co-doping only Ho3+in the BiOCl:Er3+ under 1550 nm excitation.In the BiOCl layered host,co-doping Ho3+can further enhance the red emission and simultaneously suppress the green emission of Er3+,and thus obviously improve the red-to-green(R/G) ratio.It is found that Ho3+does not se rve as ene rgy trapping through the 5 I6 state as in traditional UC materials but acts as ET bridge(4 S3/2,2 H11/2(Er3+)→5 F4,5 S2(Ho3+)→4 F9/2(Er3+)).The tuning mechanism of Ho3+is discussed in detail and further confirms through a comparative experiment.Our research gives an unusual perspective to tune the UC behavior of Er3+through co-doping Ho3+,which might be inspiring for achievement of single-band red UC emission. | Yuehong Peng Jincai Peng Jiajun Han Tianhui Wang Zhaoyi Yin Jianbei Qiu Qi W ang Zhengwen Yang Zhiguo Song | 2020 | Journal of Rare Earths2020，38，6： | 2 |
| 6 | Cypovirus capsid protein VP5 has nucleoside triphosphatase activity显示文摘As a major protein of cypovirus capsid shell, VP5 per-forms as the clamp protein to stabilize the capsid shellstructure (Yu et al., 2008). And as a part of viral RNA(vRNA) replication machinery, VP5 has been found topossess an ATP-independent RNA chaperoning activity(Yang et al., 2014). Here, we report that VP5 also has thenucleoside triphosphatase (NTPase) activity, which canhydrolyze all kinds of NTPs and dNTPs. Thus, ourfinding reveals that VP5 is a multifunctional protein thatmay be involved in diverse processes during cypovirallife cycle. | Jie Yang Qi Qian Teng—Feng Li Xueli Yang Sok Jin W on Xi Zho | 2017 | Virologica Sinica2017，32，4： | 2 |
| 7 | Cervical Intervertebral Disc Degeneration Induced by Unbalanced Dynamic and Static Forces: A Novel In Vivo Rat Model显示文摘 | Yong-Jun Wang Qi Shi W W. Lu K C. M. Cheung Michael Darowish Tian-Fang Li Yu-Feng Dong Chong-Jian Zhou Quan Zhou Zhi-jun Hu Mei Liu Qin Bian Chen-Guang Li K D. K. Luk J C. Y. Leong | 2006 | Spine2006，，14： | 2 |
| 8 | 抗生素使用的时间长短和使用时的生命阶段与全因/特定原因死亡风险的关系:一项前瞻性队列研究显示文摘过度使用抗生素一直是一个重要的临床问题,抗生素使用与肠道微生物菌群的改变有关,肠道菌群的改变与各种慢性疾病如心血管病和癌症的风险有关。此外,抗生素使用的时间可能是过早死亡的一个危险因素。研究者调查了成年期间使用抗生素的生命阶段和使用持续时间与全因和特定原因死亡风险的关系。该项前瞻性队列研究包括来自护士健康研究、均未患有心血管病或癌症的37516名年龄≥60岁的女性,收集其中年(40~59岁)和老年(≥60岁)使用抗生素的时间(无,<15d,15d至<2个月,或≥2个月)。研究者根据抗生素的使用时间估计10年内全因死亡率和心血管病或癌症的死亡风险比(HR)。在355918人年的随访中,研究者记录了所有原因导致的4536例死亡(包括728例心血管病死亡和1206例癌症死亡) | 刘青(译) 叶鹏(摘 审校) Heianza Y Ma W Li X Cao Y Chan A Rimm EB Hu FB Rexrode K Manson JE Qi L | 2020 | 中华高血压杂志2020，28，2： | 2 |
| 9 | Weighted rational cubic spline interpolation and its application显示文摘 | Duan Qi Djidjeli K Price W G | 2000 | Journal of Computational and Applied Mathematics2000，117，： | 1 |
| 10 | Preparation and electromagnetic properties of low-temperature sintered ferroelectric-ferrite composite ceramics 显示文摘 | YUE Z X CHEN S F QI X W | 2004 | J Alloys Compd2004，375，： | 1 |
| 11 | Effective program debugging based on execution slices and inter-block data dependency显示文摘 | Wong W E Qi Y | 2006 | Journal of Systems and Software2006，79，7： | 1 |
| 12 | On the construction of Boolean functions with optimal algebraic immunity显示文摘 | Li N Qu L J Qi W F | 2008 | IEEE Trans on Information Theory2008，54，3： | 1 |
| 13 | Isolation and genetic characterization of H3N8 equine influenza virus from donkeys in China显示文摘 | Qi T Guo W Huang W | 2010 | Vet Microbiol2010，144，34： | 1 |
| 14 | The roles of Kruppel-like factor6and peroxisome proliferator-activated receptor-gamma in theregulation of macrophage inflammatory protein-3alpha at earlyonset of diabetes显示文摘 | Qi W Holian J Tan CY | 2011 | Int J Biochem Cell Biol2011，43，3： | 1 |
| 15 | Size and shape dependent lattice parameters of metallic nanoparticles显示文摘 | Qi W H Wang M P | 2005 | Journal of Nanoparticle Research2005，7，1： | 1 |
| 16 | 显示文摘 | Qi W H Wang M P | 2002 | J Mater Sci Lett2002，21，： | 1 |
| 17 | molecular basis of androgen receptor diseases显示文摘 | Yong EL Lim J Qi W | 2000 | J Ann Med2000，32，1： | 1 |
| 18 | Optimization of saccharomyces cerevisiae culture in alginate-chitosan-alginate microcapsule显示文摘 | Qi w T Yu W T Xie Y B | 2005 | Biochem Eng J2005，25，9： | 1 |
| 19 | A new and simple method for concentration of enteric viruses from water显示文摘 | LI J W WANG X W Qi Yi Rui | 1998 | Journal of Virological Methods1998，，74： | 1 |
| 20 | Unbiased metabolite profiling by liquid chromatography-quadrupole time-of-flight mass spectrometry and multivariate data analysis for herbal authenticaiton: Classification of seven Lonicera species flowers buds显示文摘 | Gao W Yang H Qi L W | 2012 | J Chromatogr A2012，1245，5： | 1 |
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