|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of narcotic analgesic drugs on human Oddi's sphincter motility显示文摘AIM: To assess the effects of intramuscular analgesics(morphine, Ap-237, pethidine and tramadol) on humanOddi's sphincter motility with choledochoscope manometry.METHODS: A total of 70 patients having T tubes aftercholecystectomy and choledochotomy were assessed bycholedochoscope manometry. They were randomly dividedinto morphine group, Ap-237 group, pethidine group andtramadol group. Basal pressure of Oddi's sphincter (BPOS),amplitude of phasic contractions (SOCA), frequency ofphasic contractions (SOF), duration of phasic contractions(SOD), duodenal pressure (DP) and common bile ductpressure (CBDP) were scored and analyzed. All narcoticanalgesic drugs were administered intramuscularly.RESULTS: Levels of BPOS, SOCA and SOF were increasedafter injection of morphine and Ap-237 (P<0.05), level of CBDPwas increased from 4.97+3.87 mmHg to 8.62+7.43 mmHg(10 min later) and 7.32+5.95 mmHg (20 min later) afterinjection of morphine (P<0.01). No apparent changeoccurred after intramuscular injection of pethidine. Level ofBPOS was increased from 7.01+5.50 mmHg to 2.87+2.78 mmHg10 min after injection of tramadol and SOCA was decreasedfrom 63.34+35.29 mmHg to 45.90+27.86 mmHg (10 minlater, P<0.05) and 35.97+24.30 (20 min later, P<0.01) afteradministration of tramadol.CONCLUSION: All these findings indicate that Oddi'ssphincter manometry via choledochoscope is a practicaland new way to study the dynamics of Oddi' s sphincter.The regular dose of morphine and Ap-237 could increaseBPOS, SOF and SOCA. Morphine could increase the levelof CBDP, demonstrating an excitatory effect on the sphincterof Oddi. Pethidine had no effect on Oddi's sphincter motility.Tramadol shows an inhibitory effect on the motility of thesphincter of Oddi and decreases levels of BPOS and SOCA. | Shuo-DongWu Zhen-HaiZhang Jun-ZheJin JingKong WeiWang QiangZhang Dong-YanLi Min-FeiWang | 2004 | World Journal of Gastroenterology2004，10，19： | 15 |
| 2 | Recombinant Bivalent Vaccine against Foot-and-Mouth Disease Virus Serotype O/A Infection in Guinea Pig显示文摘In this study, two DNA fragments encoding amino acid (141–160)-(21–40)-(141–160) of the VP1 of FMDV (foot-and-mouth disease virus) serotype O and (138–160)-(21–40)-(138–160) of the serotype A FMDV were chemically synthesized. These two tandem-repeat fragments were ligated and transfected into prokaryotic expression vector pTrcHis A to construct pTH-O-A. The other vector called pTH-O-scIgG-A was constructed similarly only that the two tandem-repeat DNA fragments were linked by the bovine- IgG heavy chain coding sequence. Guinea pigs immunized with the two bivalent vaccines pTH-O-A and pTH-O-scIgG-A showed both specific antibody activity and T cell proliferation responses. FMDV challenge tests showed that 85% and 70% of guinea pigs vaccinated twice with 200 μg of the fusion protein of pTH-O-A were protected from FMDV serotype O and serotype A infection respectively. 70% and 57% of the guinea pigs immunized with the fusion protein of pTH-O-scIgG-A were protected from FMDV serotype O and serotype A infection respectively. | Jian-ZhongYI Ming-QiuLIU Cai-ZhuZHU QiangZHANG Zu-TianSHENG Wei-YaoYAN Zhao-XinZHENG | 2004 | Acta Biochimica et Biophysica Sinica2004，36，9： | 7 |
| 3 | Quantum Cutting in Tm<sup>3+</sup>/Yb<sup>3+</sup>‐Codoped Lanthanum Aluminum Germanate Glasses显示文摘 | QiangZhang BinZhu YixiZhuang GuorongChen XiaofengLiu GuangZhang JianrongQiu DanpingChen | 2010 | Journal of the American Ceramic Society2010，，3： | 2 |
| 4 | The application of superweak bioluminescence on freshness degree of chicken egg显示文摘 | Zhao Hongxia Li guochen Li Qiangzhang | 2007 | Journal of Luminescence2007，，14： | 1 |
| 5 | Integrating mitigation of air pollutants and greenhouse gases in Chinese cities:development of GAINS-City model for Beijing显示文摘 | Fei Liu Z.Klimont QiangZhang | | 0，，58： | 1 |
| 6 | Galectin‐1 attenuates astrogliosis‐associated injuries and improves recovery of rats following focal cerebral ischemia显示文摘 | Wen‐ShengQu Yi‐HuiWang Jun‐FangMa Dai‐ShiTian QiangZhang Deng‐JiPan Zhi‐YuanYu Min‐JieXie Jian‐PingWang WeiWang | 2010 | Journal of Neurochemistry2010，，2： | 1 |
| 7 | Changing properties of hydrological extremes in south China: natural variations or human influences?显示文摘 | QiangZhang TaoJiang Yongqin DavidChen XiaohongChen | 2010 | Process2010，，11： | 1 |
| 8 | An efficient binary search tree-red/black tree显示文摘 | Chen Qiangzhang | 2000 | Journal of East China Normal University : Natural Science2000，，3： | 1 |
| 9 | Effect of n‐3 polyunsaturated fatty acids on membrane microdomain localization of tight junction proteins in experimental colitis显示文摘 | QiurongLi QiangZhang MinZhang ChenyangWang ZhenxinZhu NingLi JieshouLi | 2007 | FEBS Journal2007，，3： | 1 |
| 10 | A series of furan‐aromatic polyesters synthesized via direct esterification method based on renewable resources显示文摘 | MinJiang QianLiu QiangZhang ChongYe GuangyuanZhou | 2012 | Chem2012，，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员