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| 1 | Static coarsening behaviour of lamellar microstructure in selective laser melted Ti–6Al–4V显示文摘Static coarsening mechanism of selective laser melted(SLMed) Ti–6Al–4V with a lamellar microstructure was established at temperatures from 700℃ to 950℃. Microstructure evolution revealed that high heat treatment temperature facilitated martensite decomposition and promoted lamellae growth. At each temperature, the growth rate decreased with increasing holding time. The static coarsening behaviour of SLMed Ti–6Al–4V can be interpreted by Lifshitz, Slyozov, and Wagner(LSW) theory. The coarsening coefficient were 0.33, 0.33–0.4, 0.4–0.5 for 700–800℃, 900℃ and 950℃, respectively. This indicated the coarsening mechanism was bulk diffusion at 700–800℃, and a combination of bulk diffusion and interface reaction at 900℃ and 950℃ conditions. | Sheng Cao Qiaodan Hu Aijun Huang Zhuoer Chen Ming Sun Jiahua Zhang Chenxi Fu Qingbo Jia Chao Voon Samuel Lim Rodney R.Boyer Yi Yang Xinhua Wu | 2019 | Journal of Materials Science & Technology2019,35,8: | 3 |
| 2 | Martensite transformation, mechanical properties and shape memory effects of Ni-Mn-In-Mg shape memory alloys显示文摘The martensite transformation(MT), mechanical properties and shape memory effect(SME) of(Ni_(50)Mn_(35)In_(15))_((1-x))Mg_x(x = 0%, 0.08%, 0.3%, 0.6% at%) alloys were comprehensively investigated. The results showed that due to Mg doping the MT temperature shifted to higher temperatures and a worm-like secondphase precipitated at grain boundaries and inside the grains. With increasing Mg content, the amount of precipitates gradually increased, the thermal hysteresis was almost invariant, and the SME was not obviously affected at 3% pre-strain, even when the volume of the second phase reached up to 28.75%. Compressive stress and strain experiments showed that both the strain and strength of the Ni-Mn-In-Mg alloys were improved substantially(by 46.9% and 53.4%, respectively, at x = 0.6%) compared with those of the pure Ni_(50)Mn_(35)In_(15) alloy; this effect is nearly the same as that achieved by the directional solidification method. Because Mg is nonmagnetic, the magnetization difference of the alloy with Mg doping is much lower than that of the alloy without Mg doping. Overall, the results confirm that adding a small amount of Mg is a potentially viable method for improving the mechanical properties of Ni-Mn-In alloys without adversely damaging their functional properties. | Zhenni Zhou Liang Yang Rongchen Li Jun Li Qiaodan Hu Jianguo Li | 2018 | Progress in Natural Science:Materials International2018,28,1: | 3 |
| 3 | In-situ study on hydrogen bubble evolution in the liquid Al/solid Ni interconnection by synchrotron radiation X-ray radiography显示文摘Synchrotron X-ray radiography was used to carry out an in-situ observation of the hydrogen bubble evolution in the liquid Al/solid Ni interconnection. The individual bubble mainly grows in a stochastic way during heating. The size distribution for groups of bubbles follows a Gaussian distribution in the early stage and Lifshitz-Slyozov-Wagner(LSW) diffusion controlled distribution in the final stage. The intermetallic compounds(IMCs) first form during solidification, following by the hydrogen bubbles. The bubbles between two adjacent Al3Ni grains grow unidirectionally along the liquid channel, with the bottom being impeded by the Al3Ni phase and the radius of the growth front being smaller. For the bubbles at triple junctions, they grow along the liquid channel and the crack with morphology transition. | Zongye Ding Qiaodan Hu Wenquan Lu Xuan Ge Sheng Cao Siyu Sun Tianxing Yang Mingxu Xia Jianguo Li | 2019 | Journal of Materials Science & Technology2019,35,7: | 3 |
| 4 | Effect of cooling rate on the 3D morphology of the proeutectic Al3Ni intermetallic compound formed at the Al/Ni interface after solidification显示文摘Effect of cooling rate on the 3 D morphology and the growth mechanism of the proeutectic Al3Ni intermetallic compound(IMC) that forms at the Al/Ni interface after solidification was investigated by synchrotron X-ray microtomography in combination with EBSD analysis. The proeutectic Al3Ni phase that forms under an average cooling rate of 0.1 Ks^(-1) shows a characteristic faceted growth behavior and presents a typical 3 D morphology as partially hollow quadrangular prisms. On the contrary, that forms under an average cooling rate of 10 Ks^(-1) shows complicated dendritic morphology with asymmetrically distributed arms and faceted V-shape groove at the distal end, indicating a gradual transition of the growth behavior from non-faceted to faceted during the solidification process. These results reveal that the morphology of the proeutectic Al3Ni is highly sensitive to the solidification condition so that fine control of the desired morphology may be achieved by carefully manipulating the cooling profile. | Liao Yu Qiaodan Hu Zongye Ding Fan Yang Wenquan Lu Naifang Zhang Sheng Cao Jianguo Li | 2021 | Journal of Materials Science & Technology2021,,10: | 3 |
| 5 | Recent Progress in Metallurgical Bonding Mechanisms at the Liquid/Solid Interface of Dissimilar Metals Investigated via in situ X-ray Imaging Technologies显示文摘The liquid/solid(L/S)interface of dissimilar metals is critical to the microstructure,mechanical strength,and structural integrity of interconnects in many important applications such as electronics,automotive,aeronautics,and astronautics,and therefore has drawn increasing research interests.To design preferential microstructure and optimize mechanical properties of the interconnects,it is crucial to understand the formation and growth mechanisms of diversified structures at the L/S interface during interconnecting.In situ synchrotron radiation or tube-generated X-ray radiography and tomography technologies make it possible to observe the evolution of the L/S interface directly and therefore have greatly propelled the research in this field.Here,we review the recent progress in understanding the L/S interface behaviors using advanced in situ X-ray imaging techniques with a particular focus on the following two issues:(1)interface behaviors in the solder joints for microelectronic packaging including the intermetallic compounds(IMCs)during refl ow,Sn dendrites,and IMCs during solidification and refl ow porosities and(2)growth characteristics and morphological transition of IMCs in the interconnect of dissimilar metals at high temperature.Furthermore,the main achievements and future research perspectives in terms of metallurgical bonding mechanisms under complex conditions with improved X-ray sources and detectors are remarked and discussed. | Zongye Ding Naifang Zhang Liao Yu Wenquan Lu Jianguo Li Qiaodan Hu | 2021 | Acta Metallurgica Sinica(English Letters)2021,34,2: | 3 |
| 6 | PMN-MDSCs modulated by CCL20 from cancer cells promoted breast cancer cell stemness through CXCL2-CXCR2 pathway显示文摘Our previous studies have showed that C-C motif chemokine ligand 20(CCL20)advanced tumor progression and enhanced the chemoresistance of cancer cells by positively regulating breast cancer stem cell(BCSC)self-renewal.However,it is unclear whether CCL20 affects breast cancer progression by remodeling the tumor microenvironment(TME).Here,we observed that polymorphonuclear myeloid-derived suppressor cells(PMN-MDSCs)were remarkably enriched in TME of CCL20-overexpressing cancer cell orthotopic allograft tumors.Mechanistically,CCL20 activated the differentiation of granulocyte-monocyte progenitors(GMPs)via its receptor C-C motif chemokine receptor 6(CCR6)leading to the PMN-MDSC expansion.PMN-MDSCs from CCL20-overexpressing cell orthotopic allograft tumors(CCL20-modulated PMN-MDSCs)secreted amounts of C-X-C motif chemokine ligand 2(CXCL2)and increased ALDH+BCSCs via activating CXCR2/NOTCH1/HEY1 signaling pathway.Furthermore,C-X-C motif chemokine receptor 2(CXCR2)antagonist SB225002 enhanced the docetaxel(DTX)effects on tumor growth by decreasing BCSCs in CCL20high-expressing tumors.These findings elucidated how CCL20 modulated the TME to promote cancer development,indicating a new therapeutic strategy by interfering with the interaction between PMN-MDSCs and BCSCs in breast cancer,especially in CCL20high-expressing breast cancer. | Rui Zhang Mengxue Dong Juchuanli Tu Fengkai Li Qiaodan Deng Jiahui Xu Xueyan He Jiajun Ding Jie Xia Dandan Sheng Zhaoxia Chang Wei Ma Haonan Dong Yi Zhang Lixing Zhang Lu Zhang Suling Liu | 2023 | Signal Transduction and Targeted Therapy2023,8,4: | 2 |
| 7 | Recent advances in the development of protein–protein interactions modulators:mechanisms and clinical trials显示文摘Protein–protein interactions(PPIs)have pivotal roles in life processes.The studies showed that aberrant PPIs are associated with various diseases,including cancer,infectious diseases,and neurodegenerative diseases.Therefore,targeting PPIs is a direction in treating diseases and an essential strategy for the development of new drugs.In the past few decades,the modulation of PPIs has been recognized as one of the most challenging drug discovery tasks.In recent years,some PPIs modulators have entered clinical studies,some of which been approved for marketing,indicating that the modulators targeting PPIs have broad prospects.Here,we summarize the recent advances in PPIs modulators,including small molecules,peptides,and antibodies,hoping to provide some guidance to the design of novel drugs targeting PPIs in the future. | Haiying Lu Qiaodan Zhou Jun He Zhongliang Jiang Cheng Peng Rongsheng Tong Jianyou Shi | 2020 | Signal Transduction and Targeted Therapy2020,5,1: | 2 |
| 8 | Intergrowth mechanism and morphology prediction of faceted Al_(3)Ni formed during solidification by a spatial geometric model显示文摘The interplay and intergrowth characteristic of faceted intermetallic compounds(IMCs)during solidification was originally investigated through the rod-like Al3 Ni crystals in the liquid Al/solid Ni interconnection by using synchrotron radiography,and the diversified 3-D morphologies were reconstructed by synchrotron tomography.A spatial geometric model was established to effectively predict the diversified growth patterns of two spatial crystals.For the two overlapping Al3 Ni crystals,the impeded crystal growth was divided into three different stages,decided by the hindrance form the other crystal.Further,the groove formed on the crystal surface is directly related to the solute redistribution under the critical condition of boundary layer thickness larger than two crystals distance.The closer distance and smaller crystal size indicate the deeper and larger groove,and the morphology changes from hemispheroid to hemi-ellipsoid with the increased opposite and interacted faces. | Zongye Ding Qiaodan Hu Wenquan Lu Fan Yang Yihan Zhou Naifang Zhang Sheng Cao Liao Yu Jianguo Li | 2020 | Journal of Materials Science & Technology2020,54,19: | 2 |
| 9 | Ambiguous temperature difference in aerodynamic levitation process: Modelling, solving and application显示文摘The aerodynamic levitation provides an efficient technique for the research on thermophysical properties and solidification behavior of refractory materials. However, there is a nonnegligible temperature differences across sample, causing unexpected uncertainty of measurement, such as, thermal expansivity and undercooling limit. We establish thermal filed model with properly simplified boundary condition, and derive quantitative expressions of this ambiguous temperature difference. Here we show that the temperature difference not only related to the average temperature, relative size and thermal conductivity of sample, but significantly influenced by the rotation pattern of sample. A huge temperature differences is almost inevitable when the sample with low thermal conductivity and high melting point is smelted in stationary suspension pattern, however, a drastically reduction of temperature difference can be fulfilled by simply making the sample rotation in up to down pattern. The thermal filed simulation was used to confirm the validity of these theoretical expressions. This work shed light on temperature difference in aerodynamic levitation. Based on this work, one can simply estimate the extent of temperature difference across the sample, and regulated that conveniently if needed, which benefit for novel material preparation and solidification mechanism study based on this technique. | Xuan Ge Xiaowei Xu Qiaodan Hu Wenquan Lu Liang Yang Sheng Cao Mingxu Xia Jianguo Li | 2019 | Journal of Materials Science & Technology2019,35,8: | 1 |
| 10 | Microstructures, densification and mechanical properties of TiC–Al 2 O 3 –Al composite by field-activated combustion synthesis显示文摘 | Qiaodan Hu Peng Luo Youwei Yan | 2007 | Materials Science & Engineering A2007,,1: | 1 |
| 11 | Preface to the Special Issue:Application of Synchrotron Radiation in Materials Research显示文摘Synchrotron radiation was observed for the first time by Haber et al.at General Electric in the United States in 1947 in a 70-MeV electron synchrotron.The development of synchrotron radiation light source has gone through four generations since the 1960s. | Qiaodan Hu | 2022 | Acta Metallurgica Sinica(English Letters)2022,35,1: | 1 |
| 12 | 3D morphological evolution and growth mechanism of proeutectic FeAl_(3) phases formed at Al/Fe interface under different cooling rates显示文摘The 3D morphologies and growth mechanisms of proeutectic FeAl_(3) at the Al/Fe interface under different cooling rates were studied by synchrotron X-ray tomography.With increasing cooling rate,FeAl_(3) crystals developed from faceted polygonal prism,plates with flat surface,thin ribbon-like with periodic undulating surface to non-faceted rods with radial dendrites in cross section,indicating a gradual interface growth mode transition from two-dimensional layer growth to continuous growth.At a higher cooling rate,twinning mechanism plays a leading role in the formation and growth of FeAl_(3).A link between the morphologies,twinning and crystallographic structure was established based on quantitative analyses on the 3D structures. | Naifang Zhang Qiaodan Hu Zongye Ding Wenquan Lu Fan Yang Jianguo Li | 2022 | Journal of Materials Science & Technology2022,,21: | 1 |
| 13 | Microstructures and densifieation of MoSi2 - SiC composite by field- activated and pressure-assisted combustion synthesis 显示文摘 | Hu Qiaodan Luo Peng Yan Youwei | 2009 | Journal of Alloys and Compounds2009,468,12: | 1 |
| 14 | Influence of spark plasma sintering temperature on sintering behavior and microstructures of dense hulk MoSi2 显示文摘 | Hu Qiaodan Luo Peng Yan Youwei | 2008 | Journal of Alloys and Compounds2008,459,12: | 1 |
| 15 | Effect of Cu content on microstructure and mechanical properties of in-situ β phases reinforced Ti/Zr-based bulk metallic glass matrix composite by selective laser melting(SLM)显示文摘In this study,non-toxic in-situβphases of reinforced Ti/Zr-based bulk metallic glass matrix composites(BMGCs)of(Ti_(0.65)Zr_(0.35))100-xCux(x=5,10,15 at.%)are fabricated via selective laser melting.The effect of Cu content on phase formation,microstructure,and mechanical properties is investigated.The average volume fraction and width of theβphase decreases with increasing Cu content,while a more amorphous phase and the(Ti,Zr)_(2)Cu phase forms.In the center zone of the molten pool,theβphase grows in the direction of the temperature gradient,and the amorphous phase distributes among theβphases.This occurs using:sphere morphology(for x=5),a more continuous elongated sphere and network morphology(for x=10),and network morphology(for x=15),respectively.In the edge zone of the molten pool,due to the smaller cooling rate and the existence of a partially molten zone,theβphase becomes coarser,and an amorphous phase forms for more continuous networks.Furthermore,the hardness improves significantly with increasing Cu content.No crack is found for x=5.Although the average volume fraction of theβphase for x=5 is about 90%,the compression yield strength is 1386±64 MPa,reaching to an average level of conventionally fabricated counterparts,due to finer microstructure,and twinning and martensitic transformation of theβphase. | Xuehao Gao Xin Lin Qiaodan Yan Zihong Wang Xiaobin Yu Yinghui Zhou Yunlong Hu Weidong Huang | 2021 | Journal of Materials Science & Technology2021,,8: | 1 |
| 16 | The“going global”of Chinese Fantasy Fiction through the Internet:Using I Shall Seal the Heavens on Wuxiaworld.com as an Example显示文摘In the 21st century,Chinese online fantasy fiction is gaining popularity overseas.Lai Jingping,a Chinese-American widely known online as RWX,inspired by the popularity of his translation of a Chinese fantasy fiction,Coiling Dragon,established a website called Wuxiaworld.com to disseminate Chinese fantasy culture.Now it has become the largest website in the world to translate these kinds of works.This paper,in order to explore the advantages of Wuxiaworld.com,examines the translation landscape and its trends as presented on this website,and further analyzes the translation of fiction and interactive platforms using I Shall Seal the Heavens,one of the stories on the website,as an example.Our study,through text analysis and data collection,found that Wuxiaworld.com is good at hyperlink-aided translations,and has translation awareness based on the analysis of covers,synopses and glossaries;foreignization is the main translation strategy when it comes to the fantasy terms in I Shall Seal the Heavens,while annotation in text as well as hyperlinks in the forms of text,pictures and music are adopted for cultural compensation;interactive platforms,such as comments,forums and announcements,are conducive to improving translation quality and stimulating readers’enthusiasm for these translations and Chinese culture. | Jiang Manxian Lu Qiaodan | 2021 | Contemporary Social Sciences2021,6,1: | 0 |
| 17 | Unveiling the Growth Mechanism of Faceted Primary Al_(2)Cu with Complex Morphologies During Solidification显示文摘The growth characteristic of primary faceted Al_(2)Cu intermetallic compounds(IMCs)during solidification was observed directly by synchrotron radiography.The formation and transition mechanisms of Al_(2)Cu IMCs with diverse morphologies were elucidated by first-principle calculations combined with electron backscatter diffraction analysis.The Al_(2)Cu crystals preferred to grow along the[001]direction and were bounded by{110}planes with the lowest surface energy.The faceted Al_(2)Cu rod-like clusters consisted of multiple crystals with complete rod,hollowness and partial sides,which was attributed to the increase in strain energy and solute redistribution during solidification.The faceted Al_(2)Cu with branches was characteristic with the perpendicular relationship between the main branches and side steps and partial coalescence at the junction,which was ascribed to the continuous propagation and growth of newly formed crystals along the diagonal direction. | Zongye Ding Qiaodan Hu Fan Yang Liao Yu Tianxing Yang Naifang Zhang Wenquan Lu Jingwei Yang Jian Qiao Jianguo Li | 2022 | Acta Metallurgica Sinica(English Letters)2022,35,1: | 0 |
| 18 | Can orientations of directionally solidified dual-phase Al_(2)O_(3)/YAG eutectics be induced by single-phase sapphire seeds?显示文摘Directionally solidified dual-phase Al_(2)O_(3)/Y_(3)Al_(5)O_(12)(YAG)eutectic ceramics(DSECs)typically exhibit strong anisotropy.To improve their properties,various single-phase sapphire seeds,including r-axis[1-102],m-axis[10-10],c-axis[0001],and a-axis[11-20],were used as seeds to induce the orientation of the Al_(2)O_(3)/YAG DSECs.The results showed that Al_(2)O_(3) in the eutectics could be governed by the sapphire seeds.The YAG in each induced eutectic had a specific growth direction endowed by Al_(2)O_(3) in the asinduced eutectics or the sapphire seed.Herein,we calculated the planar lattice misfits and interfacial strain energies of four crystallographic orientation relationships based on the constructed lattice models.It was elucidated the constraint of the sapphire seed caused YAG to grow following the rule of mini-mizing the interfacial strain energy.This revealed the reason why Al_(2)O_(3)/YAG DSECs orientation can be successfully induced.These results may provide a novel method for the design of high-performance eu-tectic ceramic materials. | Liangting He Xu Wang Jiaze Li Wangshuai Xiang Fuxue Yan Bailing Jiang Qiaodan Hu | 2023 | Journal of Materials Science & Technology2023,,11: | 0 |
| 19 | Metal-Free Synthesis of β-Bromoalkenyl Sulfides via Deoxygenative Bromination/Olefination/Sulfenylation of Ketones with SulfonylHydrazides and Pyridinium Tribromide显示文摘A novel metal-free method for synthesis of β-bromoalkenyl sulfides via deoxygenative bromination/olefination/sulfenylation process usingcommercially available ketones, sulfonyl hydrazides and pyridinium tribromide as starting materials has been developed. In this reaction, pyridiniumtribromide plays the role of oxidant and substrate, wherein water and molecular nitrogen are generated as environmentally benign by-products. Prelimi-nary investigation revealed that vinyl bromides were critical intermediate. Importantly, this protocol not only obviates the use of alkynes and traditionalsulfenylating agents, but also reveals that ketones can be used as precursors of vinyl bromides. | Yishu Bao Lingyu Zhong Qiaodan Hou Qingfa Zhou Fulai Yang | 2018 | Chinese Journal of Chemistry2018,36,11: | 0 |
| 20 | Development of a novel method for rapid cloning of shRNA vectors, which successfully knocked down CD44 in mesenchymal triple-negative breast cancer cells显示文摘Dear Editor,Since the discovery of short hairpin RNA(shRNA)vec-tor-mediated RNA interference(RNAi),this technology has been widely used in cancer research for its specific-ity,potency,and convenience.However,researchers may find it costly to purchase commercial vectors from bio-companies or time-and labor-consuming to construct their own shRNA vectors using traditional method by inserting annealed duplex into digested vectors.Despite intensive efforts to accelerate shRNA vector cloning in laboratories,the development of a reliable,rapid,conven-ient,and cost-effective method is still in great demand.To this end,we developed a novel method named SuperSH(Super rapid cloning of shRNA vector)for the effective and rapid construction of shRNA-expressing vectors based on high-performance DNA polymerase and seamless cloning technique[1](Additional file 1:Fig-ure S1a;the detailed methods can be found in Additional file 1).In our SuperSH method,the shRNA sequences are introduced into the vector via a pair of polymerase chain reaction(PCR)primers rather than via annealed duplex.In detail,the 3′ends of the primers are designed to bind the template to initiate a PCR to amplify the vector back-bone,and the 5′portions are designed to introduce the sequences of interest as well as to form a short homol-ogous arm for subsequent recombination via seamless cloning[1]. | Lei Zhou Dandan Sheng Qiaodan Deng Dong Wang Suling Liu | 2018 | Cancer Communications2018,38,1: | 0 |