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| 1 | Hypoglycemic mechanism of polysaccharide from Cyclocarya paliurus leaves in type 2 diabetic rats by gut microbiota and host metabolism alteration显示文摘Diabetes mellitus is a serious threat to human health.Cyclocarya paliurus(Batal.)Iljinskaja(C.paliurus)is one of the traditional herbal medicine and food in China for treating type 2 diabetes,and the C.paliurus polysaccharides(CP)were found to be one of its major functional constituents.This research aimed at investigating the hypoglycemic mechanism for CP.It was found that CP markedly attenuated the symptoms of diabetes,and inhibited the protein expression of Bax,improved the expression of Bcl-2 in pancreas of diabetic rats,normalized hormones secretion and controlled the inflammation which contributed to the regeneration of pancreaticβ-cell and insulin resistance.CP treatment increased the beneficial bacteria genus Ruminococcaceae UCG-005 which was reported to be a key genus for protecting against diabetes,and the fecal short-chain fatty acids levels were elevated.Uric metabolites analysis showed that CP treatment helped to protect with the diabetes by seven significantly improved pathways closely with the nutrition metabolism(amino acids and purine)and energy metabolism(TCA cycle),which could help to build up the intestinal epithelial cell defense for the inflammation associated with the diabetes.Our study highlights the specific mechanism of prebiotics to attenuate diabetes through multi-path of gut microbiota and host metabolism. | Qiqiong Li Jielun Hu Qixing Nie Xiao Chang Qingying Fang Junhua Xie Haishan Li Shaoping Nie | 2021 | Science China(Life Sciences)2021，64，1： | 11 |
| 2 | Weighted estimates for the multilinear commutators of the Littlewood-Paley operators显示文摘In this paper, weighted Lp estimates and sharp weighted endpoint estimates for the mul-tilinear commutators of the Littlewood-Paley operators are established. | XUE QingYing DING Yong | 2009 | Science China Mathematics2009，52，9： | 8 |
| 3 | Evaluating the Accuracy of ERA5 Wave Reanalysis in the Water Around China显示文摘Wave parameters, such as wave height and wave period, are important for human activities, such as navigation, ocean engineering and sediment transport, etc. In this study, wave data from six buoys around Chinese waters, are used to assess the quality of wave height and wave period in the ERA5 reanalysis of the European Centre for Medium-Range Weather Forecasts. Annual hourly data with temporal resolution are used. The difference between the significant wave height(SWH) of ERA 5 and that of the buoy varies from-0.35 m to 0.30 m for the three shallow locations;for the three deep locations, the variation ranges from-0.09 m to 0.09 m. The ERA5 SWH data show positive biases, indicating an overall overestimation for all locations, except for E2 and S1 where underestimation is observed. During the tropical cyclone period, a large(about 32%) underestimation of the maximum SWH in the ERA5 data is observed. Hence, the ERA5 SWH data cannot be used for design applications without site-specific validation. The difference between the annual wave period from ERA5 and the mean wave period from the buoys varies from-1.31 s to 0.4 s. Inter-comparisons suggest that the ERA5 dataset is consistent with the annual mean SWH. However, for the average period, the performance is not good, and half of the correlation coefficients in the four points are less 50%. Overall, the deep water area simulation effect is better than that in the shallow water. | SHI Hongyuan CAO Xuefeng LI Qingjie LI Delei SUN Jiacheng YOU Zaijin SUN Qingying | 2021 | Journal of Ocean University of China2021，20，1： | 5 |
| 4 | MICROSTRUCTURES AND MECHANICAL PROPERTIES OF SPUN PIPE BLANKS OF RS AlFeX ALLOY显示文摘MICROSTRUCTURESANDMECHANICALPROPERTIESOFSPUNPIPEBLANKSOFRSAlFeXALLOY①XiaoYude,LiWenxian,LiSongruiandWangRicuDepartmentofMater... | Xiao, Yude Li, Wenxian Li, Songrui Wang, Ricu Luo, Qingying | 1998 | 中国有色金属学会会刊:英文版1998，8，1： | 5 |
| 5 | ZrO2/PMMA Nanocomposites: Preparation and Its Dispersion in Polymer Matrix显示文摘ZrO2/PMMA nanocomposite particles are synthesized through an in-situ free radical emulsion polymerization based on the silane coupling agent (Z-6030) modified ZrO2 nanoparticles, and the morphology, size and its distribution of nanocomposite particles are investigated. Scanning electron microscopy (SEM) images demonstrate that the methyl methacrylate (MMA) feeding rate has a significant effect on the particle size and morphology. When the MMA feeding rate decreases from 0.42ml·min-1 to 0.08ml·min-1 , large particles (about 200-550nm) will not form, and the size distribution become narrow (36-54nm). The average nanocomposite particles size increases from 34nm to 55nm, as the MMA/ZrO2 nanoparticles mass ratio increased from 4:1 to 16:1. Regular spherical ZrO2/PMMA nanocomposite particles are synthesized when the emulsifier OP-10 concentration is 2mg·ml-1. The nanocomposite particles could be mixed with VAc-VeoVa10 polymer matrix just by magnetic stirring to prepare the ZrO2 /PMMA/VAc-VeoVa10 hybrid coatings. SEM and atomic force microscopy (AFM) photos reveal that the distribution of the ZrO2 /PMMA nanocomposite particles in the VAc-VeoVa10 polymer matrix is homogenous and stable. Here, the grafted-PMMA polymer on ZrO2 nanoparticles plays as a bridge which effectively connects the ZrO2 nanoparticles and the VAc-VeoVa10 polymer matrix with improved comparability. In consequence, the hybrid coating with good dispersion stability is obtained. | FAN Fangqiang XIA Zhengbin LI Qingying LI Zhong CHEN Huanqin | 2013 | Chinese Journal of Chemical Engineering2013，21，2： | 4 |
| 6 | General Energy Decay of Solutions for a Wave Equation with Nonlocal Damping and Nonlinear Boundary Damping显示文摘In this paper,we consider a nonlinear wave equation with nonlocal damping and nonlinear boundary damping.We prove a general energy decay property for solutions in terms of coefficient of the frictional boundary damping by using of the multiplier technique from the idea of Martinez[1],Our result extends and improves the result in the literature such as the work by Louredo,Ferreira de Araujo and Mi-randain[2]in which only exponential energy decay is considered.Furthermore,we get also the energy decay for the equation with nonlocal damping only but without nonlinear boundary damping. | LI Donghao ZHANG Hongwei HU Qingying | 2019 | Journal of Partial Differential Equations2019，32，4： | 4 |
| 7 | Stance detection via sentiment information and neural network model显示文摘Stance detection aims to automatically determine whether the author is in favor of or against a given target.In principle,the sentiment information of a post highly influences the stance.In this study,we aim to leverage the sentiment information of a post to improve the performance of stance detection.However,conventional discrete models with sentimental features can cause error propagation.We thus propose a joint neural network model to predict the stance and sentiment of a post simultaneously,because the neural network model can learn both representation and interaction between the stance and sentiment collectively.Specifically, we first learn a deep shared representation between stance and sentiment information,and then use a neural stacking model to leverage sentimental information for the stance detection task.Empirical studies demonstrate the effectiveness of our proposed joint neural model. | Qingying SUN Zhongqing WANG Shoushan LI Qiaoming ZHU Guodong ZHOU | 2019 | Frontiers of Computer Science2019，13，1： | 4 |
| 8 | Spatial learning and memory deficits in young adult mice exposed to a brief intense noise at postnatal age显示文摘Noise pollution is a major hazardous factor to human health and is likely harmful for vulnerable groups such as pre-term infants under lifesupport system in an intensive care unit. Previous studies have suggested that noise exposure impairs children's learning ability and cognitive performance and cognitive functions in animal models in which the effect is mainly attributed to the oxidant stress of noise on the cognitive brain. The potential role of noise induced hearing loss(NIHL), rather than the oxidant stress, has also been indicated by a depression of neurogenesis in the hippocampus long after a brief noise exposure, which produces only a tentative oxidant stress. It is not clear if noise exposure and NIHL during early development exerts a long term impact on cognitive function and neurogenesis towards adulthood. In the present study, a brief noise exposure at high sound level was performed in neonatal C57BL/6J mice(15 days after birth) to produce a significant amount of permanent hearing loss as proved 2 months after the noise. At this age, the noise-exposed animals showed deteriorated spatial learning and memory abilities and a reduction of hippocampal neurogenesis as compared with the control. The averaged hearing threshold was found to be strongly correlated with the scores for spatial learning and memory. We consider the effects observed are largely due to the loss of hearing sensitivity, rather than the oxidant stress, due to the long interval between noise exposure and the observations. | Shan Tao Lijie Liu Lijuan Shi Xiaowei Li Pei Shen Qingying Xun Xiaojing Guo Zhiping Yu Jian Wang | 2015 | Journal of Otology2015，10，1： | 3 |
| 9 | Recent advances on small-molecule fluorophores with emission beyond 1000 nm for better molecular imaging in vivo显示文摘In the second near-infrared channel(NIR-II, 1000–1700 nm), organic and inorganic fluorophores are designed with superior chemical/optical properties to provide real-time information with deeper penetration depth and higher resolution owing to the innate lower light scattering and absorption of the NIR-II imaging than conventional optical imaging. Among them, the small-molecule based fluorophores have been highlighted due to their desirable biocompatibility and favorable pharmacokinetics. In this review, we introduced the latest research progress of the rational design of small-molecule NIR-II fluorophores and their impressively biological applications including the NIR-II signal imaging,multimodal imaging and theranostic. | Le Tu Yuling Xu Qingying Ouyang Xiangyang Li Yao Sun | 2019 | Chinese Chemical Letters2019，30，10： | 3 |
| 10 | Cyanobacteria-based self-oxygenated photodynamic therapy for anaerobic infection treatment and tissue repair显示文摘Photodynamic therapy(PDT)is an important technique to deal with drug-resistant bacterial infections in the post-antibiotic era.However,the hypoxic environment in intractable infections such as refractory keratitis and periodontitis,makes PDT more difficult.In this work,spontaneous oxygen-producing cyanobacteria were used as the carrier of photosensitizer(Ce6),and ultrasmall Cu_(5.4)O nanoparticles(Cu_(5.4)O USNPs)with catalase activity for infection and inflammation elimination and rapid tissue repair(CeCycn-Cu_(5.4)O).The loading of Ce6 and Cu_(5.4)O USNPs onto cyanobacteria surface were confirmed by transmission electron microscopy,nano particle size analyzer,scanning electron microscopy.In vitro sterilization and biofilm removal experiments demonstrated that the restriction of hypoxic environment to PDT was significantly alleviated due to the oxygen production of cyanobacteria.Under laser irradiation,the close transfer of energy photons to oxygen produced by cyanobacteria reduced more than 90% of Ce6 dosages(660 nm,200 mW/cm^(2),2 min).It is worth mentioning that both rapid sterilization through PDT and long-term oxidized free radicals elimination were achieved by adjusting the ratio of Ce6 and Cu_(5.4)O USNPs.Both periodontitis and refractory keratitis animal models proved the excellent self-oxygenation enhanced antibacterial property and promotion of tissue repair. | Bailiang Wang Liyang Zhou Yishun Guo Hanwen Guo Yiming Zhong Xiaomin Huang Yifan Ge Qingying Wang Xiaoying Chu Yingying Jin Kaiyue Lan Mei Yang Jia Qu | 2022 | Bioactive Materials2022，7，6： | 3 |
| 11 | Enhancement of oxygen reduction reaction activity by grain boundaries in platinum nanostructures显示文摘Systematic control of grain boundary densities in various platinum(Pt)nanostructures was achieved by specific peptide-assisted assembly and coagulation of nanocrystals.A positive quadratic correlation was observed between the oxygen reduction reaction(ORR)specific activities of the Pt nanostructures and the grain boundary densities on their surfaces.Compared to commercial Pt/C,the grain-boundary-rich strain-free Pt ultrathin nanoplates demonstrated a 15.5 times higher specific activity and a 13.7 times higher mass activity.Simulation studies suggested that the specific activity of ORR was proportional to the resident number and the resident time of oxygen on the catalyst surface,both of which correlate positively with grain boundary density,leading to improved ORR activities. | Enbo Zhu Wang Xue Shiyi Wang Xucheng Yan Jingxuan Zhou Yang Liu Jin Cai Ershuai Liu Qingying Jia Xiangfeng Duan Yujing Li Hendrik Heinz Yu Huang | 2020 | Nano Research2020，13，12： | 3 |
| 12 | Preparation and Microstructure of ZrO_2-MoSi_2 Composite Powder and Compound Coating显示文摘In order to improve the lifetime of continuous casting,ZrO_2-MoSi_2 composite powder used for plasmaspraying was prepared via spray drying and vacuum sintering.The microstructure and characteristics of the powder were investigated by particle size analysis,scanning electron microscopy and X-ray diffraction,respectively.The results show that the average viscosity and settlement rate are 60.43 mPas and 1.86%,respectively,when adding ammonium polyacrylate as a dispersant and polyvinyl alcohol as a binder.The powder obtained at the solid content of 70 wt.%,the dispersant amount of 1wt.%,the binder of 10 wt.%,and the sintering temperature of 1200 'C has the spherical agglomerate and a moderate size,which can be melted on the composite coating surface with a good compactness via plasma-spraying. | ZHU Langtao ZHOU Rongping YANG Jun ZHANG Qingying | 2015 | Journal of the Chinese Ceramic Society2015，，3： | 2 |
| 13 | Application of RgMap system on digital regional geological survey显示文摘Digital geological mapping fundamentally broke through the traditional working pattern,successfully carried out the geological mapping digitalization.By using the RGMAP system to field digital geological mapping,the authors summarized the method of work and the work flow of the RGMAPGIS during the field geological survey.First,we prepared material,set up the PRB gallery,then put the geographic base map under the background maplayer and organizing the field hand map,forming the field factual datum map.At last,the geological space database is formed. | Qingying ZHAO Jinxin HE Guoliang WANG Xiumei HAN | 2007 | Global Geology2007，10，1： | 2 |
| 14 | Exponential Decay of Energy for a Logarithmic Wave Equation显示文摘 | ZHANG Hongwei LIU Gongwei HU Qingying | 2015 | Journal of Partial Differential Equations2015，28，3： | 2 |
| 15 | Decomposition Method of Complex Optimization Model Based on Global Sensitivity Analysis显示文摘The current research of the decomposition methods of complex optimization model is mostly based on the principle of disciplines, problems or components. However, numerous coupling variables will appear among the sub-models decomposed, thereby make the efficiency of decomposed optimization low and the effect poor. Though some collaborative optimization methods are proposed to process the coupling variables, there lacks the original strategy planning to reduce the coupling degree among the decomposed sub-models when we start decomposing a complex optimization model. Therefore, this paper proposes a decomposition method based on the global sensitivity information. In this method, the complex optimization model is decomposed based on the principle of minimizing the sensitivity sum between the design functions and design variables among different sub-models. The design functions and design variables, which are sensitive to each other, will be assigned to the same sub-models as much as possible to reduce the impacts to other sub-models caused by the changing of coupling variables in one sub-model. Two different collaborative optimization models of a gear reducer are built up separately in the multidisciplinary design optimization software iSIGHT, the optimized results turned out that the decomposition method proposed in this paper has less analysis times and increases the computational efficiency by 29.6%. This new decomposition method is also successfully applied in the complex optimization problem of hydraulic excavator working devices, which shows the proposed research can reduce the mutual coupling degree between sub-models. This research proposes a decomposition method based on the global sensitivity information, which makes the linkages least among sub-models after decomposition, and provides reference for decomposing complex optimization models and has practical engineering significance. | QIU Qingying LI Bing FENG Peien GAO Yu | 2014 | Chinese Journal of Mechanical Engineering2014，27，4： | 2 |
| 16 | BLOW-UP OF SOLUTIONS TO ELLIPTIC EQUATIONS WITH SEMILINEAR DYNAMICAL BOUNDARY CONDITIONS OF HYPERBOLIC TYPE显示文摘In this paper,we present some sufficient conditions for blow-up of soluti- ons to elliptic equations under semilinear dynamical boundary conditions of hyperbolic type. | Hu Qingying Zhang Hongwei | 2007 | Annals of Differential Equations2007，23，4： | 2 |
| 17 | Phenomenon of methane driven caused by hydraulic fracturing in methane-bearing coal seams显示文摘The methane concentration of the return current will always be enhanced to a certain degree when hydraulic fracturing with bedding drilling is implemented to a gassy coal seam in an underground coal mine. The methane in coal seam is driven out by hydraulic fracturing. Thus, the phenomenon is named as methane driven effect of hydraulic fracturing. After deep-hole hydraulic fracturing at the tunneling face of the gassy coal seam, the coal methane content exhibits a ‘‘low-high-low' distribution along excavation direction in the following advancing process, verifying the existence of methane driven caused by hydraulic fracturing in methane-bearing coal seam. Hydraulic fracturing causes the change of pore-water and methane pressure in surrounding coal. The uneven distribution of the pore pressure forms a pore pressure gradient. The free methane migrates from the position of high pore(methane) pressure to the position of low pore(methane) pressure. The methane pressure gradient is the fundamental driving force for methane-driven coal seam hydraulic fracturing. The uneven hydraulic crack propagation and the effect of time(as some processes need time to complete and are not completed instantaneously) will result in uneven methane driven. Therefore, an even hydraulic fracturing technique should be used to avoid the negative effects of methane driven; on the other hand, by taking fully advantage of methane driven, two technologies are presented. | Huang Bingxiang Cheng Qingying Chen Shuliang | 2016 | International Journal of Mining Science and Technology2016，26，5： | 2 |
| 18 | Chracteristics and formation setting of granodiorite in Zhalute County,Inner Mongolia显示文摘Based on field investigation and study of petrology, mineralogy, geochemistry and isotopic geochronology for the granodiorite, the authors discussed the formation setting of the granodiorite. The pluton is calci alkalic and peraluminous granite in which light rare earth elements (LREE) are intensively enriched, heavy rare earth elements are relatively poor, the ratio of LREE to heavy rare earth elements (HREE) is 7.12, and the fractionation of REE is good. The pluton formed in late orogenic setting which is relatively steady. | ZHAO Qingying LI Chunfeng WANG Guoliang LI Xuefei | 2009 | Global Geology2009，12，3： | 2 |
| 19 | Simultaneous determination and pharmacokinetic studies of dihydromyricetin and myricetin in rat plasma by HPLC-DAD after oral administration of Ampelopsis grossedentata decoction显示文摘 | ZHANG Yansong ZHANG Qingying LI Liying | 2007 | Journal of Chromatography B2007，860，： | 1 |
| 20 | Theoretical and experimental study on several refriger- ants of moderately high temperature heat pump显示文摘 | Lisheng Pan Huaixin Wang Qingying Chen | 2011 | Ap- plied Thermal Engineering2011，31，11： | 1 |
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