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| 1 | Role of mi RNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer显示文摘Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic mi RNAs and downregulated tumour-suppressor mi RNAs in this type of cancer. In this review, we provide an overview of the role of mi RNAs, pointing to their potential to be useful as diagnostic and/or prognostic biomarkers in gastric cancer. Moreover, we discuss the influence of polymorphisms and epigenetic modifications on mi RNA activity. | Kelly Cristina da Silva Oliveira Taíssa Maíra Thomaz Araújo Camila Inagaki Albuquerque Gabriela Alcantara Barata Carolina Oliveira Gigek Mariana Ferreira Leal Fernanda Wisnieski Fernando Augusto Rodrigues Mello Junior André Salim Khayat Paulo Pimentel de Assumpcao Rommel Mário Rodriguez Burbano Marília Cardoso Smith Danielle Queiroz Calcagno | 2016 | World Journal of Gastroenterology2016，22，35： | 11 |
| 2 | Physical therapy program for cervical dystonia:a study of 20 cases 显示文摘 | Queiroz MA Chien HF Sekeff-Sallem FA | 2012 | Funct Neurol2012，27，3： | 1 |
| 3 | Response of blood pressure to maximum exercise in hypertensive patients under different therapeutic programs显示文摘 | De Queiroz Carreira MA Ribeiro JC Caldas JA | 2000 | Arq Bras Cardiol2000，75，4： | 1 |
| 4 | Is abnormal adrenergic activation associated with abnormal Heart Rate Recovery显示文摘 | Messias LR Queiroz Carreira MA Miranda SM | 2012 | Arq Bras Cardiol2012，98，5： | 1 |
| 5 | 显示文摘 | Queiroz TP Hochuli- Vieira E Gabrielli MA | 2006 | Int J Oral Maxillofac Implants2006，21，1： | 1 |
| 6 | Simultaneous Plasma Lamotrigine Analysis with Carbamazepine,Carbamazepine 10,11 Epoxide,Primidone,Phenytion,Phenobarbital,and PEMA by Micellar Electrokinetic Capillary Chromatography (MECC)显示文摘 | Lancas FM Sozza MA Queiroz ME | 2003 | J Anal Toxicol2003，27，5： | 1 |
| 7 | Measurement of health-related and oral health-related quality of life among individuals with nonsyndromic orofacial clefts: a systemic review and meta-analysis 显示文摘 | Queiroz Herkrath AP Herkrath FJ Rebelo MA | 2015 | Cleft Palate Craniofac J2015，52，2： | 1 |
| 8 | Effects of renal denervation with a standard irrigated cardiac ahlation catheter on blood pressure and renal function in patients with chronic kidney disease and resistant hypertension显示文摘 | Kiuchi MG Maia GL de Queiroz Carreira MA | 2013 | Eur Heart J2013，34，28： | 1 |
| 9 | Identification of IL11RA and MELK amplification in gastric cancer by comprehensive genomic profiling of gastric cancer cell lines显示文摘AIM To identify common copy number alterations on gastric cancer cell lines.METHODS Four gastric cancer cell lines(ACP02, ACP03, AGP01 and PG100) underwent chromosomal comparative genome hybridization and array comparative genome hybridization. We also confirmed the results by fluorescence in situ hybridization analysis using the bacterial artificial chromosome clone and quantitative real time PCR analysis.RESULTS The amplification of 9p13.3 was detected in all cell lines by both methodologies. An increase in the copy number of 9p13.3 was also confirmed by fluorescence in situ hybridization analysis. Moreover, the interleukin 11 receptor alpha(IL11RA) and maternal embryonic leucine zipper kinase(MELK) genes, which are present in the 9p13.3 amplicon, revealed gains of the MELK gene in all the cell lines studied. Additionally, a gain in the copy number of IL11 RA and MELK was observed in 19.1%(13/68) and 55.9%(38/68) of primary gastric adenocarcinoma samples, respectively. CONCLUSION The characterization of a small gain region at 9p13.3 in gastric cancer cell lines and primary gastric adenocarcinoma samples has revealed MELK as a candidate target gene that is possibly related to the development of gastric cancer. | Danielle Queiroz Calcagno Sylvia Santomi Takeno Carolina Oliveira Gigek Mariana Ferreira Leal Fernanda Wisnieski Elizabeth Suchi Chen Taíssa Maíra Thomaz Araújo Eleonidas Moura Lima Maria Isabel Melaragno Samia Demachki Paulo Pimentel Assumpcao Rommel Rodriguez Burbano Marília Cardoso Smith | 2016 | World Journal of Gastroenterology2016，22，43： | 0 |
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