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| 1 | 社区老年人5年随访中痴呆等疾病的死亡率分析显示文摘为了分析痴呆致死亡的危险性并探讨其它疾病对寿命的影响,对3531名社区老年人(≥65岁)进行5年随访调查,其中的197例痴呆中Alzheimer病(AD)127例、血管性痴呆(VD)53例、其它痴呆(OD)17例。除统计死亡率外,采用Cox法予相对危险性(RR)及归因危险性(AR)分析。结果显示,痴呆的年死亡率达19.89%,其中AD、VD和OD分别为17.68%、25.70%及21.71%。按年龄分组计算,65~74岁组痴呆的RR值(AD5.35,VD7.19)接近恶性肿瘤(5.58);≥75岁组痴呆的RR值高于所有其它疾病,各种痴呆死亡归因危险性(AR合计值)高达23.71%。提示AD和VD均是导致死亡的恶性疾病,≥75岁者尤甚,亟待在社区防治中引起高度重视。 | 朱紫青 张明园 R.Katzman R.Hill | 1997 | 中华精神科杂志1997，30，4： | 22 |
| 2 | Toxoplasma gondii and Trypanosoma cruzi Antibodies in Dogs from Virginia显示文摘 | A. C.Rosypal R.Hill S.Lewis K.Braxton A. M.Zajac D. S.Lindsay | 2010 | Zoonoses and Public Health (鈥?)2010，，7： | 1 |
| 3 | Underlying solvent-based factors that influence permanent porosity in porous liquids显示文摘Porous liquids(PLs)offer the potential to combine the ready handling and mature industry status of liquid absorbents,with the high permanent porosity of metal organic frameworks.To be functional,these nanocomposites need to satisfy a number of performance parameters,such as stability and viscosity of the porogen-solvent combination,avoiding solvent penetration into metal organic framework(MOF)pores,suitable capacities,and kinetics for gas sorption.In this work,we systematically investigate the component materials to elucidate the parametric space where stable photoluminescence(PL)can be generated.In this situation,deeper conclusions were able to be drawn with regard to the influence of hydrophobicity/philicity on the properties of the resulting nanocomposites.Zeolitic imidazolate frameworks(ZIFs)were combined with a range of solvents varying in steric bulk,to deliver CO_(2)sorption capacities as high as 4.2 mmol·g^(-1)at 10 bar.These findings may have broader implications for future investigations of this tantalising field of nanocomposites. | Hamidreza Mahdavi Huacheng Zhang Lauren K.Macreadie Cara M.Doherty Durga Acharya Stefan J.DSmith Xavier Mulet Matthew R.Hill | 2022 | Nano Research2022，15，4： | 1 |
| 4 | 查看详情显示文摘 | R.Hill | | 0，，： | 1 |
| 5 | EARLY CLINICAL RESULTS FOR A NOV-EL PHASE I TRABECULAR BYPASS MI- CRO STENT显示文摘Purpose: To report the clinical data for a novel Trabecular Bypass micro stent. Methods: Six patients diagnosed with primary open angle glaucoma and insufficient IOP control, underwent implantation of the new micro stent utilizing a microinvasive ab-interno method. Two of the six patients underwent implantation of the stent in combination with cataract surgery. Results: Preliminary results include two month data on five patients | D.Spiegel W.Wetzel R.Hill | 2003 | 国际眼科杂志2003，3，1： | 0 |
| 6 | Group dynamics motivation to increase exercise intensity with a virtual partner显示文摘Background: The effect of the K?hler group dynamics paradigm(i.e., working together with a more capable partner where one's performance is indispensable to the team outcome) has been shown to increase motivation to exercise longer at a strength task in partnered exercise video games (exergames) using a software-generated partner(SGP). However, the effect on exercise intensity with an SGP has not been investigated. The purpose of this study was to examine the motivation to maintain or increase exercise intensity among healthy, physically active middle-aged adults using an SGP in an aerobic exergame.Methods: Participants(n = 85, mean age = 44.9 years) exercised with an SGP in a 6-day cycle ergometer protocol, randomly assigned to either(a)no partner control,(b) superior SGP who was not a teammate, or(c) superior SGP as a teammate(team score was dependent on the inferior member). The protocol alternated between 30-min continuous and 4-min interval lhigh-intensity session days, during which participants could change cycle power output(watts) from target intensity to alter distance and speed.Results: Mean change in watts from a targeted intensity(75% and 90% maximum heart rate) was the primary dependent variable reflecting motivational effort. Increases in performance over baseline were demonstrated without significant differences between conditions. Self-efficacy and enjoyment were significantly related to effort in the more intense interval sessions.Conclusion: Under these conditions, no K?hler effect was observed. Exercise performance during the higher-intensity interval format is more closely related to enloyment and self-efficacy beliefs compared to the continuous sessions. | Stephen Samendinger Christopher R.Hill Norbert L.Kerr Brian Winn Alison Ede James M.Pivarnik Lori Ploutz-Snyder Deborah L.Feltz | 2019 | Journal of Sport and Health Science2019，8，3： | 0 |
| 7 | Porous solid inspired hyper-crosslinked polymer liquids with highly efficient regeneration for gas purification显示文摘Separation media that combine the desired material properties within a single material for a given process remain an ongoing challenge for the gas separations in industry.Process integration of porous solid adsorbents is difficult due to their limited volumetric capacity,whereas issues of volatility and high regeneration temperatures exist for liquid amines and physical solvents.Herein,we report a family of polymer liquids inspired by hyper-crosslinked polymers(HCPs),a class of highly swellable network polymers.Compared with a chemically similar porous solid,the HCP-liquids demonstrate good volumetric capacity and improved selectivity of carbon dioxide over methane.Uptake appears to be enhanced by intramolecular swelling of the HCP-liquids at elevated pressures,while guests are strongly rejected from the HCP-liquids at slightly elevated temperatures,leading to highly efficient regeneration.Heat of adsorption and specific heat capacity of the HCP-liquids are also low,further suggesting favourable process thermodynamics.Additionally being easily prepared at scale,the presented HCP-liquids represent a promising step towards a material with the requisite properties to replace conventional scrubbing solvents to drastically reduce the footprint and energy needs of gas separations. | Stefan J.D.Smith Colin D.Wood Paul H.M.Feron Hamidreza Mahdavi Roger J.Mulder Cara M.Doherty Matthew R.Hill Xavier Mulet | 2022 | Science China Materials2022，65，7： | 0 |
| 8 | Visually Modelling Collaborative Research into Innovative Community Disaster Resilience Practice,Strategy,and Governance显示文摘In 2013 a new collaborative center was established in Wellington, New Zealand to focus on integrating resilience research with the region’s community disaster resilience strategy. An earlier study with parties to this center had indicated that researcher and practitioner groups were divided by attention to their own immediate knowledge and skills, but agreed there was a need to maximize community resilience benefits amongst a regional population. An action research workshop of researchers and practitioners used a visual logic model to focus on the pragmatic benefits of improving community resilience. The visual logic model was used to design research activities that would improve the regional community resilience strategy, which was still in an early implementation phase.Ten of 14 workshop participants were interviewed following the workshop. Statistical content analysis of interview data highlighted certain strengths of the action research process: visual monitoring and evaluation planning was a catalyst for complicated conversations between two very different groups of professionals; and researchers became more focused on practical issues as a result. Other findings suggested that in future collaborative researchgovernance would benefit from wider cycles of strategic intelligence, enhanced research contributions, and the use of different information formats for different purposes.Different formats for different purposes should also be considered when developing and implementing large-scale disaster risk reduction policies and strategies. | Thomas J.Huggins Robin Peace Stephen R.Hill David M.Johnston Alicia Cuevas Muniz | 2015 | International Journal of Disaster Risk Science2015，6，3： | 0 |
| 9 | 2014年俄勒冈州一起与娱乐用天然湖泊有关联的诺如病毒暴发显示文摘2014年7月,摩特诺玛郡(Multnomah County)公共卫生人员对一起在俄勒冈州蓝湖地区公园的游客中发生的诺如病毒暴发进行了调查。在报告病例的周末(7月11日周五至7月13日周日),约1.54万人入园游览。调查确定了65例诺如病毒感染疑似病例和5例诺如病毒感染实验室诊断病例(共70例),未报告住院病例或死亡病例。回顾性队列研究发现。 | Amy Zlot Maayan Simckes Jennifer Vines Laura Reynolds Amy Sullivan Magdalena Kendall Scott J.Michael McLuckie Dan Kromer Vincent R.Hill Jonathan S.Yoder Michele C.Hlavsa 宫宵欢 陆仁敏 | 2016 | 上海预防医学2016，28，6： | 0 |
| 10 | Retinoic acid signaling acts as a rheostat to balance Treg function显示文摘Regulatory T cells(Tregs)promote immune homeostasis by maintaining self-tolerance and regulating inflammatory responses.Under certain inflammatory conditions,Tregs can lose their lineage stability and function.Previous studies have reported that ex vivo exposure to retinoic acid(RA)enhances Treg function and stability.However,it is unknown how RA receptor signaling in Tregs influences these processes in vivo.Herein,we employed mouse models in which RA signaling is silenced by the expression of the dominant negative receptor(DN)RARαin all T cells.Despite the fact that DNRARαconventional T cells are hypofunctional,Tregs had increased CD25 expression,STAT5 pathway activation,mTORC1 signaling and supersuppressor function.Furthermore,DNRARαTregs had increased inhibitory molecule expression,amino acid transporter expression,and metabolic fitness and decreased antiapoptotic proteins.Supersuppressor function was observed when wild-type mice were treated with a pharmacologic pan-RAR antagonist.Unexpectedly,Treg-specific expression of DNRARαresulted in distinct phenotypes,such that a single allele of DNRARαin Tregs heightened their suppressive function,and biallelic expression led to loss of suppression and autoimmunity.The loss of Treg function was not cell intrinsic,as Tregs that developed in a noninflammatory milieu in chimeric mice reconstituted with DNRARαand wild-type bone marrow maintained the enhanced suppressive capacity.Fate mapping suggested that maintaining Treg stability in an inflammatory milieu requires RA signaling.Our findings indicate that RA signaling acts as a rheostat to balance Treg function in inflammatory and noninflammatory conditions in a dose-dependent manner. | Govindarajan Thangavelu Gabriela Andrejeva Sara Bolivar-Wagers Sujeong Jin Michael C.Zaiken Michael Loschi Ethan G.Aguilar Scott N.Furlan Chrysothemis C.Brown Yu-Chi Lee Cameron McDonald Hyman Colby J.Feser Angela Panoskaltsis-Mortari Keli L.Hippen Kelli P.MacDonald William J.Murphy Ivan Maillard Geoffrey R.Hill David H.Munn Robert Zeiser Leslie S.Kean Jeffrey C.Rathmell Hongbo Chi Randolph J.Noelle Bruce R.Blazar | 2022 | Cellular & Molecular Immunology2022，19，7： | 0 |
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