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| 1 | Can tranexamic acid change preoperative anemia management during total joint arthroplasty?显示文摘AIM: To investigate the postoperative transfusion and complication rates of anemic and nonanemic total joint arthroplasty patients given tranexamic acid(TXA).METHODS: A cross-sectional prospective study was conducted of primary hip and knee arthroplasty cases performed from 11/2012 to 6/2014. Exclusion criteria included revision arthroplasty, bilateral arthroplasty, acute arthroplasty after fracture, and contraindication to TXA. Patients were screened prior to surgery, with anemia was defined as hemoglobin of less than 12 g/d L for females and of less than 13 g/d L for males. Patients were divided into four different groups, based on the type of arthroplasty(total hip or total knee) and hemoglobin status(anemic or nonanemic). Intraoperatively, all patients received 2 g of intravenous TXA during surgery. Postoperatively, allogeneic blood transfusion(ABT) was directed by both clinical symptomsand relative hemoglobin change. Complications were recorded within the first two weeks after surgery and included thromboembolism, infection, and wound breakdown. The differences in transfusion and complication rates, as well as the relative hemoglobin change, were compared between anemic and nonanemic groups.RESULTS: A total of 232 patients undergoing primary joint arthroplasty were included in the study. For the total hip arthroplasty cohort, 21%(18/84) of patients presented with preoperative anemia. Two patients in the anemic group and two patients in the nonanemic group needed ABTs; this was not significantly different(P = 0.20). One patient in the anemic group presented with a deep venous thromboembolism while no patients in the nonanemic group had an acute complication; this was not significantly different(P = 0.21). For nonanemic patients, the average change in hemoglobin was 2.73 ± 1.17 g/d L. For anemic patients, the average change in hemoglobin was 2.28 ± 0.96 g/d L. Between the two groups, the hemoglobin difference of 0.45 g/d L was not significant(P = 0.13). For the total knee arthroplasty cohort, 18%(26/148) of patients presented with preoperative anemia. No patients in either group required a blood transfusion or had an acute postoperative complication. For nonanemic patients, the average change in hemoglobin was 1.85 ± 0.79 g/d L. For anemic patients, the average change in hemoglobin was 1.09 ± 0.58 g/d L. Between the two groups, the hemoglobin difference of 0.76 g/d L was significant(P < 0.001). CONCLUSION: TXA administration results in low transfusion and complication rates and may be a useful adjunct for TJA patients with preoperative anemia. | Duy L Phan Joseph B Rinehart Ran Schwarzkopf | 2015 | World Journal of Orthopedics2015,6,7: | 5 |
| 2 | Microstructure and oxygen storage capacity of Sr-modified Pt/CeO_2-ZrO_2 catalysts | Rui Ran a,Jun Fan b,Duan Weng a,a State Key Lab of New Ceramic and Fine Processing,Department of Materials Science and Engineering,Tsinghua University,Beijing 100084,China b The Administrative Centre for China’s Agenda 21,Beijing 100038,China | 2012 | Progress in Natural Science:Materials International2012,22,1: | 5 |
| 3 | ^(99m)Tc-AMD3100:A novel potential receptor-targeting radiopharmaceutical for tumor imaging显示文摘The chemokine CXCR4 receptor is over-expressed in a wide variety of tumors.In this study,AMD3100,which was a prototype non-peptide antagonist of CXCR4 receptor,was labeled with ^(99m)Tc.^(99m)Tc-AMD3100 was verified by thin layer radio chromatography(TLRC).The tumor-localizing properties of ^(99m)Tc-AMD3100 were evaluated and proved in mice bearing Hep-G2 tumor xenograft.^(99m)Tc-AMD3100 was a promising,novel receptor-specific radiopharmaceutical with potential application in the imaging of human tumors. | Jin Ming Zhang~(a,),Jia He Tian~a,Tian Ran Li~a, Hai Yu Guo~a,Li Shen~b a Department of Nuclear Medicine,The PLA General Hospital,Beijing,100853,China b Peking University Health Science Center,Beijing,100191,China | 2010 | Chinese Chemical Letters2010,21,4: | 3 |
| 4 | Mangement of Sterrte neerosis in instances of severeacute Pancreatitis显示文摘 | Ran B Pralle U Uhl W | 1995 | Jan Cell Sing1995,181,4: | 2 |
| 5 | Is Local Government Efficiency Measurement in Australia Adequate? An Analysis of the Evidence显示文摘 | Wondbury K Dollery B E Prasada Ran K S | 2003 | Public Productivity and Management Review2003,27,2: | 1 |
| 6 | Serum Thyroid Hormone Levels in Preterm Infants Born before 33 Weeks of Gestation and Association of Transient Hypothyroxinemia with Postnatal Characteristics显示文摘 | Dilek Dilli ?. Suna O?uz Nesibe And?ran U?ur Dilmen ümran Büyükka?n?c? | 2010 | Journal of Pediatric Endocrinology and Metabolism2010,,9: | 1 |
| 7 | On the nonlinear matrix equation X + A^*F(X)A = Q: solution and perturbation theory显示文摘 | Ran I C M Reurings M C B | 2002 | Linear Algebra Appl2002,346,: | 1 |
| 8 | Ageneral MPCCmodel and itssolution algorithm for continuous network design problem显示文摘 | Ban X Liu H Ferris MC Ran B | 2006 | Mathematicaland Computer Modeling2006,43,56: | 1 |
| 9 | Modeling Dynamic Transportation Networks:An Intelligent Transportation System Oriented Approach显示文摘 | RAN B BOYCE | 1996 | Springer1996,1563,: | 1 |
| 10 | Inflammatory mediator in human pancreatitis:clinlcal and pathophysiological implications显示文摘 | Mayer J Ran B Gansavge F | | 0,,04: | 1 |
| 11 | Hapten - protein conjugates prepared by the mixed anhydride method显示文摘 | Gendloff E H Casale W L Ran B P | 1986 | Journal of lmmunological Melhod1986,92,: | 1 |
| 12 | Genetic variability in rice genotypes planted in sodic soils显示文摘 | Singh R B Ran P C Singh B B | 1990 | International Rice Research Newsletter1990,15,: | 1 |
| 13 | Sorption and desorption hysteresis of organic contaminants by kerogen in a sandy aquifer material显示文摘 | Ran Y Xiao B H Fu J M | 2003 | Chemosphere2003,50,10: | 1 |
| 14 | Contents and sources of polycyclicaromatic hydrocarbons and organochlorine pesticides in vegetable soils of Guangzhou, China显示文摘 | Chen L G Ran Y Xing B S | 2005 | Chmosphere2005,60,7: | 1 |
| 15 | Gallbladder wall inflammatory cells in pediatric patients with biliary dyskinesia and cholelithiasis: A pilot study 显示文摘 | Ran B Friesen CA Daniel JF | 2006 | J Pediatr Surg2006,41,9: | 1 |
| 16 | Early severe acute panceratitis:Characteristics of a new subgroup显示文摘 | Isenmann R Ran B Beger HG | 2001 | Pancreas2001,22,3: | 1 |
| 17 | Silica retention in the Three Gorges Reservoir显示文摘 | Ran X B Yu Z G Yao Q Z | 2013 | Biogeochemistry2013,112,: | 1 |
| 18 | Novel biodegradable alpha-TCP/ poly (amino acid ) composite artificial lamina following spinal surgery for prevention of intraspinal scar adhesion 显示文摘 | Ran B Song YM Liu H | 2011 | Eur Spine J2011,20,: | 1 |
| 19 | Distributed generation: a definition 显示文摘 | Thomas Ackermann a Go'ran Andersson b Lennart So'der | 2001 | Electric Power Systems Research2001,57,2001: | 1 |
| 20 | Numerical analysis of pt utilization in pemfc catalyst layer using random cluster model显示文摘 | Wei Z D Ran H B Liu X A | | 0,,15: | 1 |