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您的检索式：作者名="RASHID Muhammad Abid"
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| 1 | Development of bis-thiobarbiturates as successful urease inhibitors and their molecular modeling studies显示文摘Bis-thiobarbiturate derivatives 1–15 have been synthesized, characterized by1 HNMR and EI-MS and screened for urease inhibition. All compounds showed various degree of urease inhibitory activity with IC_(50) values ranging 7.45 0.12 74.24 0.81 mmol/L while the standard thiourea behaved normally(IC_(50) = 21.10 0.12). Compounds 1(IC_(50) = 7.45 0.12 μmol/L), 9(IC_(50) = 18.17 1.03 μmol/L) and 13(IC_(50) = 8.61 0.45 μmol/L) showed excellent urease inhibitory activity in the series. Molecular modeling studies were performed to understand the binding site with the bimetallic nickel center of the enzyme.Structure-activity relationship has also been established for these compounds. This study identified bisthiobarbiturate as a novel class of urease inhibitors. | Fazal Rahim Muhammad Ali Shifa Ullah Umer Rashid Hayat Ullah Muhammad Taha Muhammad Tariq Javed Wajid Rehman Aftab Ahmad Khan Obaid Ur Rahman Abid Muhammad Bilal | 2016 | Chinese Chemical Letters2016，27，5： | 2 |
| 2 | Efficacy and safety of thermobalancing therapy with Dr Allen’s Device for chronic low back pain:A randomised controlled trial显示文摘BACKGROUND Lumbar disc herniation and non-specific low back pain are common conditions that seriously affect patients’health-related quality of life(HRQoL).Although empirical evidence has demonstrated that novel Thermobalancing therapy and Dr Allen’s Device can relieve chronic low back pain,there have been no randomised controlled trials for these indications.AIM To evaluate the efficacy of Dr Allen’s Device in lumbar disc herniation(LDH)and non-specific low back pain(NSLBP).METHODS A randomised clinical trial was conducted investigating 55 patients with chronic low back pain due to LDH(n=28)or NSLBP(n=27),out of which 15 were randomly assigned to the control group and 40 were assigned to the treatment group.The intervention was treatment with Dr Allen’s Device for 3 mo.Changes in HRQoL were assessed using the Numerical Pain Rating Scale and the Japanese Orthopedic Association Back Pain Questionnaire.RESULTS Thermobalancing therapy with Dr Allen’s Device showed a significant reduction in pain in the treatment group(P<0.001),with no recorded adverse effects.Both pain assessment scales showed a significant improvement in patients’perception of pain indicating improvement in HRQoL.CONCLUSION The out-of-hospital use of Thermobalancing therapy with Dr Allen’s Device for Low Back Treatment relieves chronic low back pain significantly and without adverse effects,improves the level of activity and HRQoL among patients with LDH and NSLBP.This study demonstrates the importance of this safe first-line therapy that can be used for effective at-home management of chronic low back pain. | Simon Allen Abid Rashid Ariana Adjani Muhammad Akram Fahad Said Khan Rehan Sherwani Muhammad Talha Khalil | 2023 | World Journal of Orthopedics2023，14，12： | 0 |
| 3 | Structure of [Co(im)6]SiF6:Short Hydrogen Bonds Involving SiF62- Ions显示文摘A new complex C_(18)H_(24)CoF_6N_(12)Si has been synthesized by the reaction of cobalt(II) fluoride tetrahydrate with imidazole in a glass vessel. SiF_6^(2-)was generated by in situ reaction of fluoride on silica. This complex has been characterized by different techniques such as elemental analysis, IR studies, magnetic measurements, electronic absorption measurements and single-crystal X-ray structure determination. The crystals are hexagonal in the R-3 space group, with a = 13.225(6), b = 13.225(6), c = 12.517(11) ?, and g = 120°. In complex [Co(im)_6]SiF_6, the cobalt atom is six-coordinated to adopt a regular octahedral geometry and the SiF_6^(2-)ion acts as the counter anion. The crystal displays a network structure and SiF_6^(2-) bridging hexagram formation by N-(39)···F-Si interactions between imdazole and SiF_6^(2-). SiF_6^(2-)plays an important role in assembling the supramolecular aggregates. | NAZIR Sadia ARIF Muhammad RASHID Muhammad Abid WHITWOOD Adrian Charles | 2017 | Chinese Journal of Structural Chemistry2017，36，6： | 0 |
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