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	题名	作者	年代	出处	被引量
1	Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue显示文摘AIM To evaluate brain involvement in quiescent Crohn's disease (CD) patients with fatigue using quantitative magnetic resonance imaging(MRI).METHODS Multiple MRI techniques were used to assess cerebral changes in 20 quiescent CD patients with fatigue(defined with at least 6 points out of an 11-point numeric rating scale compared with 17 healthy age and gender matched controls without fatigue. Furthermore, mental status was assessed by cognitive functioning, based on the neuropsychological inventory including the different domains global cognitive functioning, memory and executive functioning and in addition mood and quality of life scores. Cognitive functioning and mood status were correlated with MRI findings in the both study groups.RESULTS Reduced glutamate + glutamine (Glx = Glu + Gln) concentrations (P = 0.02) and ratios to total creatine(P = 0.02) were found in CD patients compared with controls. Significant increased Cerebral Blood Flow(P = 0.05) was found in CD patients (53.08 ± 6.14 mL/100 g/min) compared with controls (47.60 ± 8.62 mL/100 g/min). CD patients encountered significantly more depressive symptoms (P < 0.001). Cognitive functioning scores related to memory (P = 0.007) and executive functioning (P = 0.02) were lower in CD patients and both scores showed correlation with depression and anxiety. No correlation was found subcortical volumes between CD patients and controls in the T1-weighted analysis. In addition, no correlation was found between mental status and MRI findings.CONCLUSION This work shows evidence for perfusion, neurochemical and mental differences in the brain of CD patients with fatigue compared with healthy controls.	Sanne van Erp Ece Ercan Perla Breedveld Lianne Brakenhoff Eidrees Ghariq Sophie Schmid Matthias van Osch Mark van Buchem Bart Emmer Jeroen van der Grond Ron Wolterbeek Daniel Hommes Herma Fidder Nic van der Wee Tom Huizinga Désirée van der Heijde Huub Middelkoop Itamar Ronen Andrea van der Meulen-de Jong	2017	World Journal of Gastroenterology2017，23，6：	2
2	Ship routing and scheduling: status and perspectives 显示文摘	CHRISTIAN M FAGERHOLT K RONEN D	2004	Transportation Sci2004，38，1：	1
3	Alertness maintaining tasks(AMTs)while driving显示文摘	ORON-GILAD T RONEN A SHINAR D	2008	Accident Analysis and Prevention2008，40，3：	1
4	Short-term scheduling of vessels for shipping bulk or semi-bulk commodities originating in a single area 显示文摘	Ronen D	1986	Operations Research1986，34，1：	1
5	Langerhans cell histiocytosis in a premature baby presenting with skin-isolated disease: case report and literature review显示文摘	Aviner S Ronen M London D	2008	Acta Paediatr2008，97，12：	1
6	Alertnessmaintaining tasks (AMTs) while driving 显示文摘	0RON-GILAD T RONEN A SHINAR D	2008	AccidentAnalysis and Prevention2008，40，3：	1
7	Scheduling ocean trans- portation of cure oil 显示文摘	Brown G G Graves G W Ronen D	1987	Management Science1987，33，3：	1
8	Consolidation of customerorders into truckloads at a large manufacturer显示文摘	G G Brown D Ronen	1997	J of the Operational Research Society1997，48，8：	1
9	Ship routing and scheduling: status and perspectives显示文摘	Christiansen M Fagerhoh K Ronen D	2004	Transportation Science2004，38，1：	1
10	Ship routing and scheduling: status and perspectives 显示文摘	CHRISTIANSEN M FAGERHOLT K RONEN D	2004	Transport Science2004，38，1：	1
11	Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in andean highlanders 显示文摘	Zhou D Udpa N Ronen R	2013	Am J Human Genetics2013，93，3：	1
12	Painful piezogenic heel papules 显示文摘	Lin E Ronen M Stampler D	1985	J Bone Joint Surg Am1985，67，4：	1
13	Ship routing and scheduling: Status and perspectives显示文摘	Christiansen M Fagerholt K Ronen D	2004	Transportation Science2004，38，1：	1
14	Glyphosate transport through weathered granite soils under irrigated and non-irrigated conditions-Barcelona, Spain 显示文摘	Candela L Caballero J Ronen D	2010	Science of the Total Environment2010，408，12：	1
15	Prognostic and predictive importance of p53 and RAS for ad- juvant chemotherapy in non small-cell lung cancer显示文摘	Tsao M S Aviel Ronen S Ding K Lau D Liu N Sakurada A	2007	J Clin Oncol2007，25，：	1
16	Evaluation of flow characteristics of a sand column using magnetic resonance imaging显示文摘	Hoffman F Ronen D Pearl Z	1996	Contam Hydrol1996，22，：	1
17	An alternative pathway to β-carotene formation in plant chromoplasts discovered by map- based cloning of Beta and old gold color mutations in tomato 显示文摘	Ronen G Carmel-Goren L Zamir D	2000	PNA S2000，97，11：	1
18	Regulation of carotenoid biosynthesis during tomato fruit development: expression of the gene for lycopene epsilon-cyclase is down-regulated during ripening and is elevated in the mutant Delta 显示文摘	Ronen G Cohen M Zamir D	1999	Plant J1999，17，4：	1
19	The Effect of Oil Price on Containership Speed and Fleet Size 显示文摘	RONEN D	2010	Journal of the Operational Re- search Society2010，62，1：	1
20	Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes 显示文摘	Udpa N Ronen R Zhou D	2014	Genome Biology2014，15，2：	1

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