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| 1 | Photosynthesis, Growth and Antioxidant Metabolism in Mustard (Brassica juncea L.) Cultivars Differing in Cadmium Tolerance显示文摘Two mustard (Brassica juncea L. Czern and Coss.) cultivars, Pusa Jai Kisan and SS2 differing in cadmium (Cd) tolerance were treated with 0, 25 and 50 μmol L-1 Cd to study the physiological basis of difference in Cd tolerance. Cultivar SS2 (Cd sensitive) accumulated greater Cd in leaves than Pusa Jai Kisan (Cd tolerant). Further, SS2 also exhibited higher contents of thiobarbituric acid reactive substances (TBARS) and H2O2 and electrolyte leakage. However, the activities of antioxidant enzymes, catalase (CAT), ascorbate peroxidase (APX), dehydroascorbate reductase (DHAR), and glutathione reductase (GR) were higher in Pusa Jai Kisan than those in SS2. Contrarily, the activity of superoxide dismutase (SOD) was higher in SS2 than that in Pusa Jai Kisan and was the greatest at 25 μmol L-1 Cd. Treatment of 25 μmol L-1 Cd induced the maximum activity of enzymes. However, the activity of GR increased up to 50 μmol L-1 Cd in both the cultivars. The non-enzymatic antioxidants ascorbate (AsA) and glutathione (GSH) were higher in Pusa Jai Kisan than that in SS2, whereas dehydroascorbate (DHA) and oxidized glutathione (GSSG) were higher in SS2. Photosynthesis and growth were adversely and maximally decreased by 50 μmol L-1 Cd treatment in both the cultivars, but SS2 exhibited greater reductions. The protection of photosynthesis and growth and lesser reduction in Pusa Jai Kisan were associated with its capacity to restrict accumulation of Cd in leaves resulting in lower level of TBARS and H2O2 and electrolyte leakage. Moreover, Pusa Jai Kisan exhibited efficient antioxidant metabolism for removal of Cd-induced reactive oxygen species. | Noushina Iqbal Asim Masood Rahat Nazar Shabina Syeed Nafees A Khan | 2010 | Agricultural Sciences in China2010，9，4： | 8 |
| 2 | Tranforming growth factor beta suppresses tumor nerosis factor alpha induced matrix metallo- proteinase expression in monocytes 显示文摘 | Vaday G C Schol H Rahat M A | 2003 | J Leukoc Biol2003，69，4： | 1 |
| 3 | Fibronectin-bound TNF-alpha stimulates monocyte matrix metalloproteinase-9 expression and regulates chemotaxis显示文摘 | Vaday G G Hershkoviz R Rahat M A | 2000 | J Leukoc Biol2000，68，： | 1 |
| 4 | Role of microRNA in regulation of myeloma-related angiogenesis and survival显示文摘Multiple myeloma(MM)is a malignant disease causedby clonal proliferation of plasma cells that result in monoclonal gammopathy and severe end organ damage.Despite the uniform clinical signs,the disease is very diverse in terms of the nature and sequence of the underlying molecular events.Multiple cellular processes are involved in helping the malignant cells to remain viable and maintain proliferative properties in the hypoxic microenvironment of the bone marrow.Specifically,the process of angiogenesis,triggered by the interactions between the malignant MM cells and the stroma cells around them,was found to be critical for MM progression.In this review we highlight the current understanding about the epigenetic regulation of the proliferation and apoptosis of MM cells and its dependency on angiogenesis in the bone marrow that is carried out by different micro RNAs. | Michal A Rahat Meir Preis | 2016 | World Journal of Hematology2016，5，2： | 1 |
| 5 | MMP expression in leaking filtering blebs and tears afterglaucoma filtering surgery显示文摘 | Nurit Mathalone Sylvia Marmor Michal A Rahat | 2011 | Graefes Arch Clin ExpOphthalmol2011，249，： | 1 |
| 6 | Telomerase ac- tivity in patients with transitional cell carcinoma: a preliminary study显示文摘 | Rahat M A Lahat N Gazawi H | 1999 | Cancer1999，85，4： | 1 |
| 7 | Telomerase activity and cytokeratin 20 as markers for the detection and followup of transitional cell carcinoma: an unfulfilled promise显示文摘 | Cassel A Rahat MA Lahat N | 2001 | J Urol2001，166，3： | 1 |
| 8 | Failure of ori- gin activation in response to fork stalling leads to chromo- somal instability at fragile sites 显示文摘 | Ozeri-Galai E Lebofsky R Rahat A | 2011 | Mol Cell2011，43，1： | 1 |
| 9 | Epigenetic mecha-nisms regulate placental c-myc and Htert in normal and patho-logical pregnancies; c-myc as a novel fetal DNA epigeneticmarker for pre-eclampsia 显示文摘 | Rahat B Hamid A Ahmad Najar R | 2014 | Mol Hum Reprod2014，20，10： | 1 |
| 10 | Molecular Basis for Expression of Common and Rare Fragile Sites 显示文摘 | Zlotorynski E Rahat A Skaug J | 2003 | Molecular and Cellular Biology2003，23，20： | 1 |
| 11 | Fibronectin bound TNF-α pha stimulates monocyte matrix metalloproteinase-9 expression and regulates chemotaxis显示文摘 | VADAY G G HERSHKOVIZ R RAHAT M A | 2000 | J Leukoc Biol2000，68，5： | 1 |
| 12 | Molecular basis for expression of common and rare fragile sites显示文摘 | Zlotorynski E Rahat A Sakaug J | 2003 | Mol Cell Biol2003，23，： | 1 |
| 13 | Molecular characterization of a common fragile site(FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site显示文摘 | Mishmar D Rahat A Scherer S W | 1998 | Proc Natl Acad Sci USA1998，95，： | 1 |
| 14 | Effects of histamine HlR-H4R-agonist on the airway epithelium of rabbits显示文摘Objective:To explore the exact role of histamine receptors in respiratory system.Methods: The cohort comprised of six groups(group I control and groupⅡ—Ⅳtreated) containing five rabbits in each group.Control-group received vehicle(sterile distilled water) and treated groups received subcutaneous histamine(100μg/kg,b.i.d.),and H1R-agonist(HTMT),H2R-agonist (amthamine),H3R-agonist(R-(-)-α-methylhistamine) and H4R-agonist(clobenpropit) each in a dose of 10μg/kg,b.i.d.for 30 subsequent days.After completion of treatment,animals were euthanized and perfused with 10% buffered formalin.Small tissue blocks of trachea and lungs were processed for paraffin embedding.Observations were recorded in sample photomicrographs taken from 10μm thick.Haematoxylin and eosin stained sections.Results:It was observed that trachea and bronchi from histamine,H1R and H4R groups had only patches of hyperplastic and hypertrophied epithelium and in general,cells in the affected region were taller heaped up. The bronchiolar epithelia from all treated groups showed hypertrophy and hyperplasia throughout with most of the cells having rounded profile and appeared to bud out from the basal cells. Conclusions:It is concluded that histamine receptors on induction via its specific agonist can induce hypertrophy,hyperplasia of respiratory tract epithelia suggesting its role akin to growth stimulating factor and warranting further long-term study. | Naushad A Dilkash Trivendra Tripathi Aijaz Ahmed Khan Mohd Shahid Haris M Khan Mashiatullah Siddiqui Rahat Ali Khan | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，5： | 1 |
| 15 | Fibronectin bound TNF - alpha stimulates monocyte matrix metalloproteinase - 9 expression and regulates chemotaxis 显示文摘 | VADAY G G HERSHKOVIZ R RAHAT M A | 2000 | J Leukoc Biol2000，68，5： | 1 |
| 16 | Fibronectinbound TNF-alpha stimulates monocyte matrix metalloproteinase-9 expression and regulates chemotaxis显示文摘 | Vaday G G Hershkoviz R Rahat M A | 2000 | J Leukoc Biol2000，68，5： | 1 |
| 17 | Telomerase activity and cytokeratin 20 as markers for the detection and followup of transitional cell careinoma,an unfulfilled promise显示文摘 | Cassel A Rahat MA Lahat N | 2001 | J Urol2001，166，3： | 1 |
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