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| 1 | Itopride for gastric volume,gastric emptying and drinking capacity in functional dyspepsia显示文摘AIM To study the effect of itopride on gastric accommodation, gastric emptying and drinking capacity in functional dyspepsia(FD). METHODS Randomized controlled trial was conducted to check the effect of itopride on gastric accommodation, gastric emptying, capacity of tolerating nutrient liquid and symptoms of FD. We recruited a total of 31 patients having FD on the basis of ROME III criteria. After randomization, itopride was received by 15 patients while 16 patients received placebo. Gastric accommodation was determined using Gastric Scintigraphy. ^(13) C labeled octanoic breadth test was performed to assess gastric emptying. Capacity of tolerating nutrient liquid drink was checked using satiety drinking capacity test. Theintervention group comprised of 150 mg itopride. Patients in both arms were followed for 4 wk. RESULTS Mean age of the recruited participant 33 years(SD = 7.6) and most of the recruited individuals, i.e., 21(67.7%) were males. We found that there was no effect of itopride on gastric accommodation as measured at different in volumes in the itopride and control group with the empty stomach(P = 0.14), at 20 min(P = 0.38), 30 min(P = 0.30), 40 min(P = 0.43), 50 min(P = 0.50), 60 min(P = 0.81), 90 min(P = 0.25) and 120 min(P = 0.67). Gastric emptying done on a sub sample(n = 11) showed no significant difference(P = 0.58) between itopride and placebo group. There was no significant improvement in the capacity to tolerate liquid in the itopride group as compared to placebo(P = 0.51). Similarly there was no significant improvement of symptoms as assessed through a composite symptom score(P = 0.74). The change in QT interval in itopride group was not significantly different from placebo(0.10). CONCLUSION Our study found no effect of itopride on gastric accommodation, gastric emptying and maximum tolerated volume in patients with FD. | Shahab Abid Wasim Jafri Maseeh Uz Zaman Rakhshanda Bilal Safia Awan Aamir Abbas | 2017 | World Journal of Gastrointestinal Pharmacology and Therapeutics2017，8，1： | 6 |
| 2 | Association of nit rogenfixing plant growth promoting rhizobateria (PGPR) with kallar grass and rice 显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 3 | Association of nitrogen-fixing plant growth promoting Rhizobateria (PGPR) with Kallar grass and rice显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 4 | Association of Nitrogen-fixing Plant Growth Promoting Rhizobateria (PGPR) with Kallar Grass and Rice显示文摘 | MALIK K A RAKHSHANDA B | 1997 | Plant and Soil1997，194，： | 1 |
| 5 | Association of nitrogen-fixing plant growth promoting rhizobateria(PGPR)with kallar grass and rice显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 6 | Association of NitrogenFixing Plant Growth Promoting Rhizobateria (PGPR)with Kallar Grass and Rice 显示文摘 | Malik K A Rakhshanda Bilal | 1997 | Plant and Soil1997，194，： | 1 |
| 7 | Association of nitrogen-fixing plant growth promoting rhizobateria (PGPR) with Kallar grass and rice显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 8 | Association of Nitrogen-Fixing Plant Growth Promoting Rhizobateria (PGPR) with Kallar Grass and Rice显示文摘 | Mallk K A Rakhshanda Bilal | 1997 | Plant and Soil1997，194，： | 1 |
| 9 | Optimization of alkaline extraction of natural dye from Henna leaves and its dyeing on cotton by exhaust method 显示文摘 | Shaukat Ali Tanveer Hussain Rakhshanda Nawaz | 2009 | Journal of Cleaner Production2009，17，： | 1 |
| 10 | Association of nitrogen-fixing plant growth promoting rhizobateria (PGPR) with Kallar grass and Rice 显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，1： | 1 |
| 11 | Association of Nitrogen-Fixing Plant Growth Promoting Rhizobateria (PGPR) with Kallar Grass and Rice 显示文摘 | Malik K A Rakhshanda Bilal | 1997 | Plant and Soil1997，49，7： | 1 |
| 12 | Association of nitrogen-fixing plant growth promoting rhizobateria(PGPR) with Kallar grass and Rice显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 13 | Association of nitrogen-fixing plant growth promoting rhizobateria (PGPR) with kallar grass and rice显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 14 | Association of nitrogen- fixing plant growth promoting rhizobacteria(PGPR) with kallar grass and rice 显示文摘 | MaliK K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 15 | Association of nitrogen-fixing plant growth promoting Rhizobacteria (PGPR) with Kallar grass and rice显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 16 | Association of nitrogen fixing plant growth promoting rhizobateria(PGPR) with kallar grassand rice 显示文摘 | MALIK K A RAKHSHANDA BILAL | 1997 | Plant and Soi11997，194，： | 1 |
| 17 | Association of nitrogenfixing plant growth promoting rhizobateria (PGPR) with kallar grass and rice显示文摘 | Malik K A Rakhshanda B | 1997 | Plant and Soil1997，194，： | 1 |
| 18 | Optimization of alkaline extraction of natural dye from Henna leaves and its dyeing on cotton by ex- haust method 显示文摘 | SHAUKAT A TANVEER H RAKHSHANDA N | 2009 | Journal of Cleaner Production2009，17，： | 1 |
| 19 | Association of nitrogen-fixing plantgrowt hpromoting rhizobateria (PGPR) with kallar grass and rice 显示文摘 | Malik K A Rakhshanda B | 1997 | Plant Soil1997，194，： | 1 |
| 20 | New development of cardiac tamponade on underlying effusive–constrictive pericarditis: an uncommon initial presentation of scleroderma显示文摘 | Stalin R Subramanian Rakhshanda Akram Arash Velayati Hal Chadow | 2013 | Case Reports (jul )2013，，122： | 1 |
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