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| 1 | Plant Cell Wall Matrix Polysaccharide Biosynthesis显示文摘一个膨胀植物房间的墙首先由与结构、酶的蛋白质的小数量一起在 hemicellulosic 和果胶的多糖的一个矩阵嵌入的纤维素 microfibrils 组成。矩阵多糖在 Golgi 被综合并且在他们在纤维素 microfibrils 之中设置的地方,由 exocytosis 出口了到房间墙,它在血浆膜被做并且直接扔了进房间墙。在导致植物生长素的房间扩大的 Golgi glucan 合成的参与长被认出了;然而,仅仅最近,相应于 glucan synthases 的基因被识别了。因为易变的性质并且很,生物化学的纯化是失败的低许多这些酶。Mutational 遗传也证明无效。通过基因表示在系统由功能的描述跟随了的 heterologous 介绍或比较 genomics 识别的候选人基因的表示是相对成功的。从家庭被发现了涉及各种各样的 hemicellulosic glycans 的合成的纤维素象 synthase 一样(Csl ) 的几基因。然而,这条途径的实用性被限制到可能不形成由无关的蛋白质组成的建筑群的那些酶。Nonconventional 途径将逐渐地继续解开 Golgi 多糖生合成的机制。 | Ajay Pal S. Sandhu Gursharn S. Randhawa Kanwarpal S. Dhugga | 2009 | Molecular Plant2009，2，5： | 14 |
| 2 | 世界家庭医生组织(WONCA)研究论文摘要汇编——基层医疗机构应用直肠指检筛查前列腺癌的系统综述及Meta分析显示文摘目的尽管临床上经常应用直肠指检筛查前列腺癌,但是关于其在基层医疗机构中的应用的文献报道还为数尚少。本文旨在对在基层医疗机构中应用直肠指检筛查前列腺癌准确性的研究进行综述及Meta分析。方法检索Medline、EMBase、DARE(效果评价研究综述摘要数据库)、Cochrane临床对照试验数据库、Cochrane系统综述数据库、CINAHL(护理和联合卫生文献累积索引)等数据库中有关基层医疗机构中应用直肠指检筛查前列腺癌的研究,检索时间范围为自建库起至2016年6月。6例研究人员分为3组分别进行文献筛选和数据提取。对纳入文献中的直肠指检筛查前列腺癌的敏感性、特异性、阳性预测值、阴性预测值进行逆方差meta分析。采用诊断准确性研究质量评价工具QUADAS-2和GRADE指南对纳入文献的偏倚风险和质量进行评估。结果初步检索出相关文献8 217篇,最终纳入7篇,共计9 241例患者。所有患者均做了直肠指检和活检。直肠指检的敏感性为0.51[95%CI(0.36,0.67);特异性为0.59[95%CI(0.41,0.76);阳性预测值为0.41[95%CI(0.31,0.52);],阴性预测值为0.64[95%CI(0.58,0.70);]。GRADE评价表明,文献质量很低。结论鉴于缺乏证据支持其准确性,本研究不建议基层医疗机构常规应用直肠指检筛查前列腺癌。 | NAJI L RANDHAWA H SOHANI Z | 2018 | 中国全科医学2018，21，16： | 8 |
| 3 | “Plasma Cell Hepatitis” in Liver Allografts: Identification and Characterization of an IgG4‐Rich Cohort显示文摘 | M. Castillo‐Rama M. Sebagh E. Sasatomi P. Randhawa K. Isse A. D. Salgarkar K. Ruppert A. Humar A. J. Demetris | 2013 | American Journal of Transplantation2013，，11： | 2 |
| 4 | Impact of gut microbiome in the development and treatment of pancreatic cancer:Newer insights显示文摘The gut microbiome plays an important role in the variation of pharmacologic response.This aspect is especially important in the era of precision medicine,where understanding how and to what extent the gut microbiome interacts with drugs and their actions will be key to individualizing therapy.The impact of the composition of the gut microbiome on the efficacy of newer cancer therapies such as immune checkpoint inhibitors and chimeric antigen receptor T-cell treatment has become an active area of research.Pancreatic adenocarcinoma(PAC)has a poor prognosis even in those with potentially resectable disease,and treatment options are very limited.Newer studies have concluded that there is a synergistic effect for immunotherapy in combination with cytotoxic drugs,in the treatment of PAC.A variety of commensal microbiota can affect the efficacy of conventional chemotherapy and immunotherapy by modulating the tumor microenvironment in the treatment of PAC.This review will provide newer insights on the impact that alterations made in the gut microbial system have in the development and treatment of PAC. | Ayrton I Bangolo Chinmay Trivedi Ishan Jani Silvanna Pender Hirra Khalid Budoor Alqinai Alina Intisar Karamvir Randhawa Joseph Moore Nicoleta De Deugd Shaji Faisal SuchithBoodgere Suresh Parva Gopani Vignesh K Nagesh Tracy Proverbs-Singh Simcha Weissman | 2023 | World Journal of Gastroenterology2023，29，25： | 2 |
| 5 | DNA sequencing of viral capsid protein VP1 region in patients with BK virus interstitial nephritis 显示文摘 | Randhawa PS Khaleel-UR-Rehman K Swalsky PA | 2002 | Transplantation2002，73，： | 1 |
| 6 | Fas/Fas ligand interaction in human colorectal hepatic metastases: a mechanism of hepatocyte destruction to facilitate local tumor invasion显示文摘 | Yoong K F Afford S C Randhawa S | 1999 | Am J Pathol1999，154，3： | 1 |
| 7 | A comparative study on the thermal decomposition of some transition metal maleates and furnarates显示文摘 | Randhawa B S Kaur M | | 0，，01： | 1 |
| 8 | Glomerular changes in BK virus nephropathy显示文摘 | Celik B Randhawa P S | 2004 | Hum Pathol2004，35，3： | 1 |
| 9 | Frequency of diastolic dysfunction in asymptomatic, normotensive type-2 di- abetic patients显示文摘 | Randhawa FA Hussnain MT Nazir S | 2014 | J Ayub Med Coll Abbottabad2014，26，1： | 1 |
| 10 | Field incurred chlorpyrifos and 3, 5, 6-trichloro-2-pyridinol residues in fresh and processed vegetables显示文摘 | Randhawa MA Muhammad AF Anwaar A | 2007 | Food Chemistry2007，103，3： | 1 |
| 11 | Insulin accelerates inter-endosomal GLUT4 traffic via phosphatidylinositol 3- kinase and protein Kinase B显示文摘 | Faster LJ Li D Randhawa VK | 2001 | J Biol Chem2001，276，47： | 1 |
| 12 | Monitoring for polyomavirus BK and JC in Urine: comparison of quantitative polymerase chain reaction with urine cytology 显示文摘 | Randhawa P Vats A Shapiro R | 2005 | Transplantation2005，79，8： | 1 |
| 13 | Preva-lence of vitamin A deficiency in South Asia:causes,outcomes,and possible remedies显示文摘 | Akhtar S Ahmed A Randhawa MA? | 2013 | J Health PopulNutr2013，，： | 1 |
| 14 | Distribution patterns of BK polyomavirus(BKV)subtypes and subgroups in American,European and Asian populations suggest co-migration of BKV and the human race显示文摘 | Zhong S Randhawa PS Ikegaya H | 2009 | J Gen Virol2009，90，1： | 1 |
| 15 | Study of spatial relation- ship of phrenic nerves with cardiac structures relevant to eleetrophys- iologie interventions 显示文摘 | Randhawa A Sahni D Aggarwal A | 2014 | Pacing Clin Electrophysiol2014，37，： | 1 |
| 16 | The role of the insulin-like growth factor system in prenatal growth 显示文摘 | Randhawa R Cohen P | 2005 | Mol Genet Metab2005，86，12： | 1 |
| 17 | Preparation and characterization of Paliperidone loaded solid lipid nanoparticles显示文摘 | Kumar S Randhawa JK | 2013 | Colloids Surf B : Biointerfaces2013，102，： | 1 |
| 18 | BK polyomavirus in solid organ transplantation显示文摘 | Hirsch HH Randhawa P | 2013 | Am J Transplant2013，134，： | 1 |
| 19 | Field incurred chlorpyrifos and 3,5,6-trichloro-2 pyridinol residues in fresh and processed vegetables显示文摘 | Randhawa M A Anjum F M Ahmed A | 2007 | Food Chemistry2007，103，： | 1 |
| 20 | Pathogenesis and management of polyomavirus infection in transplant recipients 显示文摘 | Kwak EJ Vilchez RA Randhawa P | 2002 | Clin Infect Dis2002，35，： | 1 |
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