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| 1 | Inflammatory bowel disease:Therapeutic limitations and prospective of the stem cell therapy显示文摘Inflammatory bowel disease(IBD),consisting primarily of ulcerative colitis and Crohn’s disease,is a group of debilitating auto-immune disorders,which also increases the risk of colitis-associated cancer.However,due to the chronic nature of the disease and inconsistent treatment outcomes of current anti-IBD drugs(e.g.,approximately 30%non-responders to anti-TNFαagents),and related serious side effects,about half of all IBD patients(in millions)turn to alternative treatment options.In this regard,mucosal healing is gaining acceptance as a measure of disease activity in IBD patients as recent studies have correlated the success of mucosal healing with improved prognosis.However,despite the increasing clinical realization of the significance of the concept of mucosal healing,its regulation and means of therapeutic targeting remain largely unclear.Here,stemcell therapy,which uses hematopoietic stem cells or mesenchymal stem cells,remains a promising option.Stem cells are the pluripotent cells with ability to differentiate into the epithelial and/or immune-modulatory cells.The overreaching concept is that the stem cells can migrate to the damaged areas of the intestine to provide curative help in the mucosal healing process.Moreover,by differentiating into the mature intestinal epithelial cells,the stem cells also help in restoring the barrier integrity of the intestinal lining and hence prevent the immunomodulatory induction,the root cause of the IBD.In this article,we elaborate upon the current status of the clinical management of IBD and potential role of the stem cell therapy in improving IBD therapy and patient’s quality of life. | Rangnath Mishra Punita Dhawan Anand S Srivastava Amar B Singh | 2020 | World Journal of Stem Cells2020，12，10： | 4 |
| 2 | Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine显示文摘 | Devang M. Patel Jainy Shah Anand S. Srivastava Rangnath Mishra | 2013 | Stem Cells International2013，，： | 1 |
| 3 | Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine显示文摘 | Devang M. Patel Jainy Shah Anand S. Srivastava Rangnath Mishra | 2013 | Stem Cells International2013，，： | 1 |
| 4 | Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine显示文摘 | Devang M. Patel Jainy Shah Anand S. Srivastava Rangnath Mishra | 2013 | Stem Cells International2013，，： | 1 |
| 5 | Transient composite electron field disturbances near dip equator associated with auroral substorm 显示文摘 | SASTRI J H RAMESH K B RANGNATH RAO H N | 1992 | Geophys1992，19，14： | 1 |
| 6 | Hight glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells 显示文摘 | Rangnath M Steven E Timothy K | 2005 | Kidney Int2005，67，1： | 1 |
| 7 | Hight glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells 显示文摘 | Rangnath M Steven E Timothy K | 2005 | Kidney Int2005，67，1： | 1 |
| 8 | Hight glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells显示文摘 | RANGNATH M STEVEN E TIMOTHY K | 2005 | Kidney int2005，67，1： | 1 |
| 9 | Hight glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells显示文摘 | Rangnath M Steven E Timothy K | 2005 | Kidney Int2005，67，1： | 1 |
| 10 | Perfect Image Segmentation Using Pulse Coupled Neural Networks显示文摘 | G Kuntimad H S Rangnath | 1999 | IEEE Trans on Neural Networks1999，10，3： | 1 |
| 11 | Combustion-assisted synthesis of Ti-TiB-TiC composite via the casting route显示文摘 | Vijayakumar M Subrahmanyam J | 1992 | Mater Sci Eng1992，149，： | 1 |
| 12 | A review on particulate-reinforced titanium matrix composites 显示文摘 | RANGNATH S | 1997 | Journal of Materials Science1997，32，1： | 1 |
| 13 | Dexamethasone facilitates erythropoiesis in murine embryonic stem cells differentiating into hematopoietic cells in vitro显示文摘 | Anand S. Srivastava Sharmeela Kaushal Rangnath Mishra Thomas A. Lane Ewa Carrier | 2006 | Biochemical and Biophysical Research Communications2006，，2： | 1 |
| 14 | Perfect Image Segmentation Using Pulse Coupled Neural Networks 显示文摘 | Kuntimad G Rangnath H S | 1999 | IEEE Trans on Neural Network s1999，10，3： | 1 |
| 15 | Combustion-assisted synthesis of Ti-TiB-TiC composite via the casting route 显示文摘 | Rangnath S Vijayakumar M Subrahmanyam J | 1992 | Mater Sci Eng A1992，149，： | 1 |
| 16 | High glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells 显示文摘 | Rangnath M Emancipator SN Timothy K | 2005 | Kidney Intl2005，67，1： | 1 |
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