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5篇 您的检索式：作者名="Raskind R"

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		题名	作者	年代	出处	被引量
	1	Mutation of a putative mitochondrial iron transporter gene (ABC7) in Xlinked sideroblastic anemia and ataxia (XLSA/A)显示文摘	Allikmets R Raskind WH Hutchinson A		0，，5：	1
	2	Vertebral artery injuries following chiropractic cervical spine manipulation: Case reports 显示文摘	Raskind R North CM	1990	Angiology1990，41，：	1
	3	Prospective evaluation of arthroscopically assisted anterior cruciate ligament reconstruction显示文摘	Marder RA Raskind J R Carroll M	1991	Am J Sports Med1991，19，5：	1
	4	Effect of tacrine on language,praxis,and noncognitive behavioral problems in Alzheimer disease显示文摘	RASKIND M A SADOWSKY C H SIGMUND W R	1997	Arch Neurol1997，54，：	1
	5	Pancreatic intraductal papillary mucinous neoplasm in a patient with Lynch syndrome显示文摘Intraductal papillary mucinous neoplasm(IPMN) is a mucin-producing epithelial neoplasm that carries a risk of progression to invasive pancreatic ductal adenocarcinoma.Lynch syndrome is an autosomal dominant condition caused by germline mutations in mismatch repair genes such as MSH2 that lead to microsatellite instability and increased risk of tumor formation.Although families with Lynch syndrome have an increased risk of pancreatic cancer, a clear connection between Lynch syndrome and IPMN has not been drawn.We present a report of a 58 year-old Caucasian woman with multiple cancers and a germline mutation of MSH2 consistent with Lynch syndrome.A screening abdominal computed tomography scan revealed a dilated main pancreatic duct and cystic ductular structure in the uncinate process that were consistent with IPMN of the main pancreatic duct on excision.Immunohistochemistry and polymerase chain reaction of the patient's pancreas specimen did not reveal microsatellite instability or mismatch repair gene loss of expression or function.Our findings may be explained by the fact that loss of mismatch repair function and microsatellite instability is a late event in neoplastic transformation.Given the relative rarity of main duct IPMN, its appearance in the setting of somatic MSH2 mutation suggests that IPMN may fit into the constellation of Lynch syndrome related malignancies.	Meghan R Flanagan Arjun Jayaraj Wei Xiong Matthew M Yeh Wendy H Raskind Venu G Pillarisetty	2015	World Journal of Gastroenterology2015，21，9：	1

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