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| 1 | 显示文摘 | RAYK A TSCHUIKOW-ROUX E T CHEN Y H | 1993 | J Phys Chem1993，97，30： | 1 |
| 2 | Liver cancer: The promise of new approaches in themanagement of hepatocellular carcinoma - adding to thetoolbox? 显示文摘 | RayK | 2013 | Nature Reviews Gastroenterology and Hepa-tology2013，10，4： | 1 |
| 3 | Investigation on defect distribution and its statistical evaluation for case hardened material states显示文摘 | Rayk Thumser Susanne Kleemann Joachim W. Bergmann Andreas Kleemann | 2012 | International Journal of Fatigue2012，，： | 1 |
| 4 | IκB Kinase 2 Is Essential for IgE-Induced Mast Cell De Novo Cytokine Production but Not for Degranulation显示文摘 | Katrin Peschke Anke Weitzmann Klaus Heger Rayk Behrendt Nadja Schubert Julia Scholten David Voehringer Karin Hartmann Anne Dudeck Marc Schmidt-Supprian Axel Roers | 2014 | Cell Reports2014，，5： | 1 |
| 5 | Human macrophages limit oxidation products in low density lipoprotein显示文摘 | Hulten LM Ullstrom C Krettek A Von Rayk D Marklund SL Dahlgren C | 2005 | Lipids Health Dis2005，4，1： | 1 |
| 6 | Prognostic utility of apoB/Al,total eholesterol/HDL,non-HDL cholesterol or hsCRP as predictors of clinical risk inpatients receiving statin therapy after acute coronary syndromes显示文摘 | Rayk K Cannon CP Cairns R | | 0，，03： | 1 |
| 7 | RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma显示文摘Radiotherapy induces DNA damage,resulting in cell cycle arrest and activation of cell-intrinsic death pathways.However,the radioresistance of some tumour entities such as malignant melanoma limits its clinical application.The innate immune sensing receptor retinoic acid-inducible gene I(RIG-I)is ubiquitously expressed and upon activation triggers an immunogenic form of cell death in a variety of tumour cell types including melanoma.To date,the potential of RIG-I ligands to overcome radioresistance of tumour cells has not been investigated.Here,we demonstrate that RIG-I activation enhanced the extent and immunogenicity of irradiation-induced tumour cell death in human and murine melanoma cells in vitro and improved survival in the murine B16 melanoma model in vivo.Transcriptome analysis pointed to a central role for p53,which was confirmed using p53^(-/-)B16 cells.In vivo,the additional effect of RIG-I in combination with irradiation on tumour growth was absent in mice carrying p53^(-/-)B16 tumours,while the antitumoural response to RIG-I stimulation alone was maintained.Our results identify p53 as a pivotal checkpoint that is triggered by RIG-I resulting in enhanced irradiation-induced tumour cell death.Thus,the combined administration of RIG-I ligands and radiotherapy is a promising approach to treating radioresistant tumours with a functional p53 pathway,such as melanoma. | Silke Lambing Yu Pan Tan Paraskevi Vasileiadou Stefan Holdenrieder Patrick Müller Christian Hagen Stephan Garbe Rayk Behrendt Martin Schlee Jasper G.van den Boorn Eva Bartok Marcel Renn Gunther Hartmann | 2023 | Journal of Molecular Cell Biology2023，15，1： | 0 |
| 8 | 色彩传感器的选择显示文摘三种成本—效益型方案各有千秋。 | JackBerlien RayKing | 2003 | 今日电子2003，，8： | 0 |
| 9 | 高效节能的制造车架显示文摘开姆尼茨市霍伦霍夫机床技术和成形加工技术研究所IWU与其合作伙伴大众股份公司、Ortlinghaus有限责任公司和Sibea有限责任公司为汽车车架制造研发了一套机械化的专用系统。利用这一系统可以高效节能的完成车架生产制造。同时,大大缩短了产品生产时间,避免了经常更换模具和更快、更有效的收回投资。 | Rayk Fritzsche Andreas Richter Marko Pfeifer | 2013 | 现代制造2013，，27： | 0 |
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