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| 1 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 2 | Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases 显示文摘 | Coucouvanis E O'Reilly MS Marshall B | 1998 | J Clin Invest1998，10，1： | 1 |
| 3 | Risk Factors for Death among Children Less Than 5 Years Old Hospitalized with Diarrhea in Rural Western Kenya, 2005 -2007 : A Cohort Study 显示文摘 | 0' Reilly C E Jaron P Ochieng B et 01 | 2012 | PLoS Medicine2012，9，00： | 1 |
| 4 | Modified t-z model-a software for tension piles显示文摘 | REDDY E S B O'REILLY M CHAPMAN D | 1998 | Computers and Structures1998，68，： | 1 |
| 5 | Pyrrolizidine alkaloids in human diet显示文摘 | Prakash A S Pereira T N Reilly P E B | 1999 | Mutat Res1999，443，： | 1 |
| 6 | Dietary flavonoids andrisk of stroke in women显示文摘 | CASSIDY A RIMM E B O'REILLY E J LOGOROSCINO G KAY C CHIUVE S E REXRODE K M | 2012 | Stroke2012，43，： | 1 |
| 7 | Ocean color chlorophyll algorithms for SeaWiFS显示文摘 | O'REILLY J E MARITORENA S MITCHELL B G | 1998 | J Geophys Res1998，103，24： | 1 |
| 8 | Evidence for a synergistic interaction between cadmium and cndotoxin toxicity and for nitric oxide and cadmium displacement of metals in the kidney显示文摘 | SATARUG S BAKER J R REILLY P E B | 2000 | Nitric Oxide2000，，4： | 1 |
| 9 | Cadmium levels in the lung, liver, kidney cortex and urinesamples from Australians without occupational exposure to metals 显示文摘 | Satarug S Baker J R Reilly P E B | 2002 | Arch Environ Health2002，57，1： | 1 |
| 10 | Ocean color chlorophyll algorithms for SeaWiFS显示文摘 | O'REILLY J E MARITORENA S MITCHELL B G | 1998 | Journal of Geophysieal Research1998，103，24： | 1 |
| 11 | Ocean color chloro- phyll algorithms for SeaWiFS显示文摘 | O' Reilly J E Maritorena S Mitchell B | 1998 | Journal of Geophsical Research1998，103，24： | 1 |
| 12 | Chem Phys Lett显示文摘 | Yuk J S O'Reilly E Forster R J MaeCraith B D McDonagh C | 2011 | 513:ll22011，513，： | 1 |
| 13 | Microphthalmia transcription factor immunohistoehemistry: a useful diagnos- tic marker in the diagnosis and detection of cutaneous melanoma, sentinel lymph node metastases, and extracutaneous melanocytic neoplasms 显示文摘 | O'Reilly F M Brat D J McAlpine B E | 2001 | J Am Acad Dermatol2001，45，3： | 1 |
| 14 | Evidence for a synergistic interaction between cadmium and endotoxin toxicity and for nitric oxide and cadmium displacement of metals in the kidney显示文摘 | Satarug S Baker J R Reilly P E B | | 0，，： | 1 |
| 15 | Assessment of recent process analytical technology (PAT) trends: a multiauthor review显示文摘 | Simon L L Pataki H Marosi G Meemken F Hungerbiihler K Baiker A Tummala S Glennon B Kuentz M Steele G Kramer H J M Rydzak J W Chen Z Morris J Kjell F Singh R Gani R Gernaey K V Louhi-Kultanen M O'Reilly J Sandler N Antikainen 0 Yliruusi J Frohberg P Ulrich J Braatz R D Leyssens T von Stosch M Oliveira R Tan R B H Wu H Khan M O'Grady D Pandey A Westra R Delle-Case E Pape D Angelosante D Maret Y Steiger 0 Lenner M Abbou-Oucherif'K Nagy Z K Litster J D Kamaraju V K Chiu M-S | 2015 | Organic Process Research & Development2015，19，1： | 1 |
| 16 | Ocean color chlorophyll algorithms for SeaWiFS显示文摘 | O'REILLY J E MARITORENA S MITCHELL B G | 1998 | J Geophys Res Atmos1998，103，24： | 1 |
| 17 | Carcinogenicity risk assessment supports the chronic safety of dapagliflozin,an inhibitor of sodium-glucose co-transporter 2,in the treatment of type 2 diabetes mellitus显示文摘 | Reilly T P Graziano M J Janovitz E B | 2014 | Diabetes Ther2014，5，1： | 1 |
| 18 | Management of the patient and family with neurofibromatosis 2:a consensus conference statement显示文摘 | Evans D G R Baser M E O'Reilly B | | 0，，01： | 1 |
| 19 | Ocean color chlorophyll algorithms for SeaWiFS显示文摘 | O'Reilly J E Maritorena S Mitchell B G | 1998 | Journal of Geophysical Research1998，103，24： | 1 |
| 20 | Major types of dietary fat and risk of coronary heart disease:a pooled analysis of 11 cohort studies显示文摘 | Jakobsen M U O’Reilly E J Heitmann B L | 2009 | Am J Clin Nutr2009，89，： | 1 |
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