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| 1 | Biological therapy in inflammatory bowel diseases:Access in Central and Eastern Europe显示文摘Biological drugs opened up new horizons in the management of inflammatory bowel diseases(IBD).This study focuses on access to biological therapy in IBD patients across 9 selected Central and Eastern European(CEE)countries,namely Bulgaria,the Czech Republic,Estonia,Hungary,Latvia,Lithuania,Poland,Romania and Slovakia.Literature data on the epidemiology and disease burden of IBD in CEE countries was systematically reviewed.Moreover,we provide an estimation on prevalence of IBD as well as biological treatment rates.In all countries with the exception of Romania,lower biological treatment rates were observed in ulcerative colitis(UC)compared to Crohn’s disease despite the higher prevalence of UC.Great heterogeneity(up to 96-fold)was found in access to biologicals across the CEE countries.Poland,Bulgaria,Romania and the Baltic States are lagging behind Hungary,Slovakia and the Czech Republic in their access to biologicals.Variations of reimbursement policy may be one of the factors explaining the differences to a certain extent in Bulgaria,Latvia,Lithuania,and Poland,but association with other possible determinants(differences in prevalence and incidence,price of biologicals,total expenditure on health,geographical access,and cost-effectiveness results)was not proven.We assume,nevertheless,that healthdeterioration linked to IBD might be valued differently against other systemic inflammatory conditions in distinct countries and which may contribute to the immense diversity in the utilization of biological drugs for IBD.In conclusion,access to biologicals varies widely among CEE countries and this difference cannot be explained by epidemiological factors,drug prices or total health expenditure.Changes in reimbursement policy could contribute to better access to biologicals in some countries. | Fanni Rencz Márta Péntek Martin Bortlik Edyta Zagorowicz Tibor Hlavaty Andrzej Sliwczyński Mihai M Diculescu Limas Kupcinskas Krisztina B Gecse László Gulácsi Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，6： | 4 |
| 2 | Application of fuzzy set theory for integration of geological, geophysical and remote sensing data 显示文摘 | An P Moon W M Rencz A | 1991 | Canadian Journal of Exploration Geophysics1991，27，： | 1 |
| 3 | Digital lithology map- ping from airborne geophysical and remote sensing data in the Melville Peninsula, Northern Canada, using a neural network approach 显示文摘 | An P Chung C F Rencz A N | 1995 | Remote Sensing of Environment1995，53，2： | 1 |
| 4 | Application of fuzzy set theory to integrated mineral exploration显示文摘 | An P Moon W M Rencz A | 1991 | Canadian Journal of Exploration Geophysics1991，27，： | 1 |
| 5 | Tracing the thermal behavior of ICs 显示文摘 | SZEKELY V RENCZ M COURTOIS B | 1998 | IEEE Design & Test of Computers1998，2，15： | 1 |
| 6 | Application of fuzzy set theory for integration of geological,geophysical and remote sensing data显示文摘 | An P Moon W M Rencz A | 1991 | Canadian Journal of Exploration Geophysics1991，27，： | 1 |
| 7 | The relation between spectral reflectance and dissolved organic carbon in lake water: Kejimkujik National Park, Nova Scotia, Canada显示文摘 | Hirtle H Rencz A | 2003 | International Journal of Remote Sensing2003，24，5： | 1 |
| 8 | Measuring partial thermal re- sistances in a heat-flow path显示文摘 | Rencz M R Szekely V | 2002 | IEEE Transa-ctions on Components and Packing Technologies2002，25，4： | 1 |
| 9 | Application of Fuzzy Set Theory to Integrated Mineral Exploration显示文摘 | P An W M Moon A Rencz | 1991 | Canadian Journal of Exploration Geophysics1991，27，： | 1 |
| 10 | Defection of Mountain Pine Beetle Infestation Using Landsat Mss and Simulated Thematic Mapper Data显示文摘 | Rencz A N Nemeth J | 1985 | Canadian Journal of Remote Sensing1985，11，： | 1 |
| 11 | Digital Lithology Mapping from Airborne Geophysical and Remote Sensing Data in the Melville Peninsula, Norhem Canada, Using a Neural Network Approach 显示文摘 | An P Chung C F Rencz A N | 1995 | Remote Sensing of Environment1995，53，： | 1 |
| 12 | Recent Progress of Thermal Interface Material Research-An Overview显示文摘 | Johan Liu Bruno Michel Marta Rencz etc | 2008 | THERMINIC2008，9，： | 1 |
| 13 | The relation between spectral reflectance and dissolved organic carbon in lake water:Kejimkujik National Park,Nova Scotia,Canada显示文摘 | Hirtle H Rencz A | 2003 | INT J of Remote Sensing2003，24，5： | 1 |
| 14 | Health technology assessment in Poland, the Czech Republic, Hungary, Romania and Bulgaria显示文摘 | László Gulácsi Alexandru M. Rotar Maciej Niewada Olga L?blová Fanni Rencz Guenka Petrova Imre Boncz Niek S. Klazinga | 2014 | The European Journal of Health Economics2014，，1： | 1 |
| 15 | Comparative bioavailability of alpha-methyldopa normal and film tablet formulations after single oral adminstration in healthy volunteers显示文摘 | Rona K Ary K Renczes G | 2001 | Eur J Drug Metab Pharmacokinet2001，26，12： | 1 |
| 16 | Transferability of results of cost utility analyses for biologicals in inflammatory conditions for Central and Eastern European countries显示文摘 | László Gulácsi Fanni Rencz Márta Péntek Valentin Brodszky Ruth Lopert Noémi V. Hevér Petra Baji | 2014 | The European Journal of Health Economics2014，，1： | 1 |
| 17 | Increasing the accuracy of thermal transient measurements显示文摘 | Sekely V Rencz M | 2002 | IEEE T Compon Pack T2002，25，4： | 1 |
| 18 | Geographic information system are being applied to mineral resource assessment in Northern New Brunswick 显示文摘 | Watson G P Rencz A N Bonham-Carter G F | 1989 | GEOS1989，18，1： | 1 |
| 19 | Detection of mountain pine beetle infestation using Landsat MSS and simulated thematic mapper data显示文摘 | Rencz A N Nemeth J | 1985 | Can J Remote Sens1985，，11： | 1 |
| 20 | Geographic information system are being applied to mineral resource assessment in Northern New Brunswick显示文摘 | Watson G P Rencz A N Bonham Carte G F | 1989 | GEOS1989，18，1： | 1 |
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